BMP2K

BMP2 inducible kinase, also known as BMP2K, is a human gene.cite web | title = Entrez Gene: BMP2K BMP2 inducible kinase| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=55589| accessdate = ]

PBB_Summary
section_title =
summary_text = This gene is the human homolog of mouse BMP-2-inducible kinase. Bone morphogenic proteins (BMPs) play a key role in skeletal development and patterning. Expression of the mouse gene is increased during BMP-2 induced differentiation and the gene product is a putative serine/threonine protein kinase containing a nuclear localization signal. Therefore, the protein encoded by this human homolog is thought to be a protein kinase with a putative regulatory role in attenuating the program of osteoblast differentiation. Two transcript variants encoding different isoforms have been found for this gene.cite web | title = Entrez Gene: BMP2K BMP2 inducible kinase| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=55589| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Hoffmann A, Gross G |title=BMP signaling pathways in cartilage and bone formation. |journal=Crit. Rev. Eukaryot. Gene Expr. |volume=11 |issue= 1-3 |pages= 23–45 |year= 2002 |pmid= 11693963 |doi=
*cite journal | author=Ueki N, Oda T, Kondo M, "et al." |title=Selection system for genes encoding nuclear-targeted proteins. |journal=Nat. Biotechnol. |volume=16 |issue= 13 |pages= 1338–42 |year= 1999 |pmid= 9853615 |doi= 10.1038/4315
*cite journal | author=Kearns AE, Donohue MM, Sanyal B, Demay MB |title=Cloning and characterization of a novel protein kinase that impairs osteoblast differentiation in vitro. |journal=J. Biol. Chem. |volume=276 |issue= 45 |pages= 42213–8 |year= 2001 |pmid= 11500515 |doi= 10.1074/jbc.M106163200
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Gevaert K, Goethals M, Martens L, "et al." |title=Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides. |journal=Nat. Biotechnol. |volume=21 |issue= 5 |pages= 566–9 |year= 2004 |pmid= 12665801 |doi= 10.1038/nbt810
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Arikawa T, Omura K, Morita I |title=Regulation of bone morphogenetic protein-2 expression by endogenous prostaglandin E2 in human mesenchymal stem cells. |journal=J. Cell. Physiol. |volume=200 |issue= 3 |pages= 400–6 |year= 2004 |pmid= 15254968 |doi= 10.1002/jcp.20031
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Medici M, van Meurs JB, Rivadeneira F, "et al." |title=BMP-2 gene polymorphisms and osteoporosis: the Rotterdam Study. |journal=J. Bone Miner. Res. |volume=21 |issue= 6 |pages= 845–54 |year= 2006 |pmid= 16753015 |doi= 10.1359/jbmr.060306
*cite journal | author=Olsen JV, Blagoev B, Gnad F, "et al." |title=Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. |journal=Cell |volume=127 |issue= 3 |pages= 635–48 |year= 2006 |pmid= 17081983 |doi= 10.1016/j.cell.2006.09.026

PBB_Controls
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