POLRMT

Polymerase (RNA) mitochondrial (DNA directed), also known as POLRMT, is a human gene.cite web | title = Entrez Gene: POLRMT polymerase (RNA) mitochondrial (DNA directed)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=5442| accessdate = ]

PBB_Summary
section_title =
summary_text = This gene encodes a mitochondrial DNA-directed RNA polymerase. The gene product is responsible for mitochondrial gene expression as well as for providing RNA primers for initiation of replication of the mitochondrial genome. Although this polypeptide has the same function as the three nuclear DNA-directed RNA polymerases, it is more closely related to RNA polymerases of phage and mitochondrial polymerases of lower eukaryotes.cite web | title = Entrez Gene: POLRMT polymerase (RNA) mitochondrial (DNA directed)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=5442| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. |journal=Gene |volume=138 |issue= 1-2 |pages= 171–4 |year= 1994 |pmid= 8125298 |doi=
*cite journal | author=Tiranti V, Savoia A, Forti F, "et al." |title=Identification of the gene encoding the human mitochondrial RNA polymerase (h-mtRPOL) by cyberscreening of the Expressed Sequence Tags database. |journal=Hum. Mol. Genet. |volume=6 |issue= 4 |pages= 615–25 |year= 1997 |pmid= 9097968 |doi=
*cite journal | author=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, "et al." |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library. |journal=Gene |volume=200 |issue= 1-2 |pages= 149–56 |year= 1997 |pmid= 9373149 |doi=
*cite journal | author=Falkenberg M, Gaspari M, Rantanen A, "et al." |title=Mitochondrial transcription factors B1 and B2 activate transcription of human mtDNA. |journal=Nat. Genet. |volume=31 |issue= 3 |pages= 289–94 |year= 2002 |pmid= 12068295 |doi= 10.1038/ng909
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=McCulloch V, Shadel GS |title=Human mitochondrial transcription factor B1 interacts with the C-terminal activation region of h-mtTFA and stimulates transcription independently of its RNA methyltransferase activity. |journal=Mol. Cell. Biol. |volume=23 |issue= 16 |pages= 5816–24 |year= 2003 |pmid= 12897151 |doi=
*cite journal | author=Grimwood J, Gordon LA, Olsen A, "et al." |title=The DNA sequence and biology of human chromosome 19. |journal=Nature |volume=428 |issue= 6982 |pages= 529–35 |year= 2004 |pmid= 15057824 |doi= 10.1038/nature02399
*cite journal | author=Graziewicz MA, Longley MJ, Bienstock RJ, "et al." |title=Structure-function defects of human mitochondrial DNA polymerase in autosomal dominant progressive external ophthalmoplegia. |journal=Nat. Struct. Mol. Biol. |volume=11 |issue= 8 |pages= 770–6 |year= 2004 |pmid= 15258572 |doi= 10.1038/nsmb805
*cite journal | author=Gaspari M, Falkenberg M, Larsson NG, Gustafsson CM |title=The mitochondrial RNA polymerase contributes critically to promoter specificity in mammalian cells. |journal=EMBO J. |volume=23 |issue= 23 |pages= 4606–14 |year= 2005 |pmid= 15526033 |doi= 10.1038/sj.emboj.7600465
*cite journal | author=Kravchenko JE, Rogozin IB, Koonin EV, Chumakov PM |title=Transcription of mammalian messenger RNAs by a nuclear RNA polymerase of mitochondrial origin. |journal=Nature |volume=436 |issue= 7051 |pages= 735–9 |year= 2005 |pmid= 16079853 |doi= 10.1038/nature03848
*cite journal | author=Wang Z, Cotney J, Shadel GS |title=Human mitochondrial ribosomal protein MRPL12 interacts directly with mitochondrial RNA polymerase to modulate mitochondrial gene expression. |journal=J. Biol. Chem. |volume=282 |issue= 17 |pages= 12610–8 |year= 2007 |pmid= 17337445 |doi= 10.1074/jbc.M700461200

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