INPP1

INPP1

Inositol polyphosphate-1-phosphatase, also known as INPP1, is a human gene.cite web | title = Entrez Gene: INPP1 inositol polyphosphate-1-phosphatase| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3628| accessdate = ]

PBB_Summary
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summary_text = INPP1 encodes the enzyme inositol polyphosphate-1-phosphatase, one of the enzymes involved in phosphatidylinositol signaling pathways. This enzyme removes the the phosphate group at position 1 of the inositol ring from the polyphosphates inositol 1,4-bisphosphate and inositol 1,3,4-trisphophosphate.cite web | title = Entrez Gene: INPP1 inositol polyphosphate-1-phosphatase| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3628| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Majerus PW, Ross TS, Cunningham TW, "et al." |title=Recent insights in phosphatidylinositol signaling. |journal=Cell |volume=63 |issue= 3 |pages= 459–65 |year= 1990 |pmid= 2225061 |doi=
*cite journal | author=Zhang X, Majerus PW |title=Phosphatidylinositol signalling reactions. |journal=Semin. Cell Dev. Biol. |volume=9 |issue= 2 |pages= 153–60 |year= 1998 |pmid= 9599410 |doi= 10.1006/scdb.1997.0220
*cite journal | author=York JD, Veile RA, Donis-Keller H, Majerus PW |title=Cloning, heterologous expression, and chromosomal localization of human inositol polyphosphate 1-phosphatase. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=90 |issue= 12 |pages= 5833–7 |year= 1993 |pmid= 8390685 |doi=
*cite journal | author=Steen VM, Løvlie R, Osher Y, "et al." |title=The polymorphic inositol polyphosphate 1-phosphatase gene as a candidate for pharmacogenetic prediction of lithium-responsive manic-depressive illness. |journal=Pharmacogenetics |volume=8 |issue= 3 |pages= 259–68 |year= 1998 |pmid= 9682271 |doi=
*cite journal | author=Løvlie R, Gulbrandsen AK, Molven A, Steen VM |title=Genomic structure and sequence analysis of a human inositol polyphosphate 1-phosphatase gene (INPP1). |journal=Pharmacogenetics |volume=9 |issue= 4 |pages= 517–28 |year= 2000 |pmid= 10780272 |doi=
*cite journal | author=Patel S, Yenush L, Rodríguez PL, "et al." |title=Crystal structure of an enzyme displaying both inositol-polyphosphate-1-phosphatase and 3'-phosphoadenosine-5'-phosphate phosphatase activities: a novel target of lithium therapy. |journal=J. Mol. Biol. |volume=315 |issue= 4 |pages= 677–85 |year= 2002 |pmid= 11812139 |doi= 10.1006/jmbi.2001.5271
*cite journal | author=Piccardi MP, Ardau R, Chillotti C, "et al." |title=Manic-depressive illness: an association study with the inositol polyphosphate 1-phosphatase and serotonin transporter genes. |journal=Psychiatr. Genet. |volume=12 |issue= 1 |pages= 23–7 |year= 2002 |pmid= 11901356 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504

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Look at other dictionaries:

  • INPP1 — inositol polyphosphate 1 phosphatase …   Medical dictionary

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