JMJD2C

Jumonji domain containing 2C, also known as JMJD2C, is a human gene.cite web | title = Entrez Gene: JMJD2C jumonji domain containing 2C| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=23081| accessdate = ]

PBB_Summary
section_title =
summary_text = This gene is a member of the Jumonji domain 2 (JMJD2) family and encodes a protein with one JmjC domain, one JmjN domain, two PHD-type zinc fingers, and two Tudor domains. This nuclear protein functions as a trimethylation-specific demethylase, converting specific trimethylated histone residues to the dimethylated form. Chromosomal aberrations and increased transcriptional expression of this gene are associated with esophageal squamous cell carcinoma.cite web | title = Entrez Gene: JMJD2C jumonji domain containing 2C| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=23081| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Nagase T, Ishikawa K, Suyama M, "et al." |title=Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. |journal=DNA Res. |volume=5 |issue= 5 |pages= 277–86 |year= 1999 |pmid= 9872452 |doi=
*cite journal | author=Yang ZQ, Imoto I, Fukuda Y, "et al." |title=Identification of a novel gene, GASC1, within an amplicon at 9p23-24 frequently detected in esophageal cancer cell lines. |journal=Cancer Res. |volume=60 |issue= 17 |pages= 4735–9 |year= 2000 |pmid= 10987278 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Katoh M, Katoh M |title=Identification and characterization of JMJD2 family genes in silico. |journal=Int. J. Oncol. |volume=24 |issue= 6 |pages= 1623–8 |year= 2004 |pmid= 15138608 |doi=
*cite journal | author=Humphray SJ, Oliver K, Hunt AR, "et al." |title=DNA sequence and analysis of human chromosome 9. |journal=Nature |volume=429 |issue= 6990 |pages= 369–74 |year= 2004 |pmid= 15164053 |doi= 10.1038/nature02465
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Kimura K, Wakamatsu A, Suzuki Y, "et al." |title=Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. |journal=Genome Res. |volume=16 |issue= 1 |pages= 55–65 |year= 2006 |pmid= 16344560 |doi= 10.1101/gr.4039406
*cite journal | author=Whetstine JR, Nottke A, Lan F, "et al." |title=Reversal of histone lysine trimethylation by the JMJD2 family of histone demethylases. |journal=Cell |volume=125 |issue= 3 |pages= 467–81 |year= 2006 |pmid= 16603238 |doi= 10.1016/j.cell.2006.03.028
*cite journal | author=Cloos PA, Christensen J, Agger K, "et al." |title=The putative oncogene GASC1 demethylates tri- and dimethylated lysine 9 on histone H3. |journal=Nature |volume=442 |issue= 7100 |pages= 307–11 |year= 2006 |pmid= 16732293 |doi= 10.1038/nature04837
*cite journal | author=Wissmann M, Yin N, Müller JM, "et al." |title=Cooperative demethylation by JMJD2C and LSD1 promotes androgen receptor-dependent gene expression. |journal=Nat. Cell Biol. |volume=9 |issue= 3 |pages= 347–53 |year= 2007 |pmid= 17277772 |doi= 10.1038/ncb1546
*cite journal | author=Katoh Y, Katoh M |title=Comparative integromics on JMJD2A, JMJD2B and JMJD2C: preferential expression of JMJD2C in undifferentiated ES cells. |journal=Int. J. Mol. Med. |volume=20 |issue= 2 |pages= 269–73 |year= 2007 |pmid= 17611647 |doi=

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