FGL1

Fibrinogen-like 1, also known as FGL1, is a human gene.cite web | title = Entrez Gene: FGL1 fibrinogen-like 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=2267| accessdate = ]

PBB_Summary
section_title =
summary_text = Fibrinogen-like 1 is a member of the fibrinogen family. This protein is homologous to the carboxy terminus of the fibrinogen beta- and gamma- subunits which contains the four conserved cysteines of fibrinogens and fibrinogen related proteins. However, this protein lacks the platelet-binding site, cross-linking region and a thrombin-sensitive site which are necessary for fibrin clot formation. This protein may play a role in the development of hepatocellular carcinomas. Four alternatively spliced transcript variants encoding the same protein exist for this gene.cite web | title = Entrez Gene: FGL1 fibrinogen-like 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=2267| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. |journal=Gene |volume=138 |issue= 1-2 |pages= 171–4 |year= 1994 |pmid= 8125298 |doi=
*cite journal | author=Yamamoto T, Gotoh M, Sasaki H, "et al." |title=Molecular cloning and initial characterization of a novel fibrinogen-related gene, HFREP-1. |journal=Biochem. Biophys. Res. Commun. |volume=193 |issue= 2 |pages= 681–7 |year= 1993 |pmid= 8390249 |doi= 10.1006/bbrc.1993.1678
*cite journal | author=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, "et al." |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library. |journal=Gene |volume=200 |issue= 1-2 |pages= 149–56 |year= 1997 |pmid= 9373149 |doi=
*cite journal | author=Hara H, Yoshimura H, Uchida S, "et al." |title=Molecular cloning and functional expression analysis of a cDNA for human hepassocin, a liver-specific protein with hepatocyte mitogenic activity. |journal=Biochim. Biophys. Acta |volume=1520 |issue= 1 |pages= 45–53 |year= 2001 |pmid= 11470158 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Zeng L, Dai J, Ying K, "et al." |title=Identification of a novel human angiopoietin-like gene expressed mainly in heart. |journal=J. Hum. Genet. |volume=48 |issue= 3 |pages= 159–62 |year= 2003 |pmid= 12624729 |doi= 10.1007/s100380300025
*cite journal | author=Yan J, Yu Y, Wang N, "et al." |title=LFIRE-1/HFREP-1, a liver-specific gene, is frequently downregulated and has growth suppressor activity in hepatocellular carcinoma. |journal=Oncogene |volume=23 |issue= 10 |pages= 1939–49 |year= 2004 |pmid= 14981537 |doi= 10.1038/sj.onc.1207306
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Rual JF, Venkatesan K, Hao T, "et al." |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209
*cite journal | author=Rijken DC, Dirkx SP, Luider TM, Leebeek FW |title=Hepatocyte-derived fibrinogen-related protein-1 is associated with the fibrin matrix of a plasma clot. |journal=Biochem. Biophys. Res. Commun. |volume=350 |issue= 1 |pages= 191–4 |year= 2006 |pmid= 16996032 |doi= 10.1016/j.bbrc.2006.09.018
*cite journal | author=Liu Z, Ukomadu C |title=Fibrinogen-like protein 1, a hepatocyte derived protein is an acute phase reactant. |journal=Biochem. Biophys. Res. Commun. |volume=365 |issue= 4 |pages= 729–34 |year= 2008 |pmid= 18039467 |doi= 10.1016/j.bbrc.2007.11.069

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