EXTL1

Exostoses (multiple)-like 1, also known as EXTL1, is a human gene.cite web | title = Entrez Gene: EXTL1 exostoses (multiple)-like 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=2134| accessdate = ]

PBB_Summary
section_title =
summary_text = This gene is a member of the multiple exostoses (EXT) family of glycosyltransferases, which function in the chain polymerization of heparan sulfate and heparin. The encoded protein harbors alpha 1,4- N-acetylglucosaminyltransferase activity, and is involved in chain elongation of heparan sulfate and possibly heparin.cite web | title = Entrez Gene: EXTL1 exostoses (multiple)-like 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=2134| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Zak BM, Crawford BE, Esko JD |title=Hereditary multiple exostoses and heparan sulfate polymerization. |journal=Biochim. Biophys. Acta |volume=1573 |issue= 3 |pages= 346–55 |year= 2003 |pmid= 12417417 |doi=
*cite journal | author=Wise CA, Clines GA, Massa H, "et al." |title=Identification and localization of the gene for EXTL, a third member of the multiple exostoses gene family. |journal=Genome Res. |volume=7 |issue= 1 |pages= 10–6 |year= 1997 |pmid= 9037597 |doi=
*cite journal | author=Xu L, Xia J, Jiang H, "et al." |title=Mutation analysis of hereditary multiple exostoses in the Chinese. |journal=Hum. Genet. |volume=105 |issue= 1-2 |pages= 45–50 |year= 1999 |pmid= 10480354 |doi=
*cite journal | author=Wuyts W, Spieker N, Van Roy N, "et al." |title=Refined physical mapping and genomic structure of the EXTL1 gene. |journal=Cytogenet. Cell Genet. |volume=86 |issue= 3-4 |pages= 267–70 |year= 2000 |pmid= 10575224 |doi=
*cite journal | author=Kim BT, Kitagawa H, Tamura J, "et al." |title=Human tumor suppressor EXT gene family members EXTL1 and EXTL3 encode alpha 1,4- N-acetylglucosaminyltransferases that likely are involved in heparan sulfate/ heparin biosynthesis. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=98 |issue= 13 |pages= 7176–81 |year= 2001 |pmid= 11390981 |doi= 10.1073/pnas.131188498
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Mathysen D, Van Roy N, Van Hul W, "et al." |title=Molecular analysis of the putative tumour-suppressor gene EXTL1 in neuroblastoma patients and cell lines. |journal=Eur. J. Cancer |volume=40 |issue= 8 |pages= 1255–61 |year= 2004 |pmid= 15110891 |doi= 10.1016/j.ejca.2004.01.013
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Kimura K, Wakamatsu A, Suzuki Y, "et al." |title=Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. |journal=Genome Res. |volume=16 |issue= 1 |pages= 55–65 |year= 2006 |pmid= 16344560 |doi= 10.1101/gr.4039406
*cite journal | author=Gregory SG, Barlow KF, McLay KE, "et al." |title=The DNA sequence and biological annotation of human chromosome 1. |journal=Nature |volume=441 |issue= 7091 |pages= 315–21 |year= 2006 |pmid= 16710414 |doi= 10.1038/nature04727

PBB_Controls
update_page = yes
require_manual_inspection = no
update_protein_box = yes
update_summary = yes
update_citations = yes