ENDOG

ENDOG

Endonuclease G, also known as ENDOG, is a human gene.cite web | title = Entrez Gene: ENDOG endonuclease G| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=2021| accessdate = ]

PBB_Summary
section_title =
summary_text = The protein encoded by this gene is a nuclear encoded endonuclease that is localized in the mitochondrion. The encoded protein is widely distributed among animals and cleaves DNA at GC tracts. This protein is capable of generating the RNA primers required by DNA polymerase gamma to initiate replication of mitochondrial DNA.cite web | title = Entrez Gene: ENDOG endonuclease G| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=2021| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Tiranti V, Rossi E, Ruiz-Carrillo A, "et al." |title=Chromosomal localization of mitochondrial transcription factor A (TCF6), single-stranded DNA-binding protein (SSBP), and endonuclease G (ENDOG), three human housekeeping genes involved in mitochondrial biogenesis. |journal=Genomics |volume=25 |issue= 2 |pages= 559–64 |year= 1995 |pmid= 7789991 |doi=
*cite journal | author=Prats E, Noël M, Létourneau J, "et al." |title=Characterization and expression of the mouse endonuclease G gene. |journal=DNA Cell Biol. |volume=16 |issue= 9 |pages= 1111–22 |year= 1997 |pmid= 9324313 |doi=
*cite journal | author=Li LY, Luo X, Wang X |title=Endonuclease G is an apoptotic DNase when released from mitochondria. |journal=Nature |volume=412 |issue= 6842 |pages= 95–9 |year= 2001 |pmid= 11452314 |doi= 10.1038/35083620
*cite journal | author=Ohsato T, Ishihara N, Muta T, "et al." |title=Mammalian mitochondrial endonuclease G. Digestion of R-loops and localization in intermembrane space. |journal=Eur. J. Biochem. |volume=269 |issue= 23 |pages= 5765–70 |year= 2003 |pmid= 12444964 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Lemarié A, Lagadic-Gossmann D, Morzadec C, "et al." |title=Cadmium induces caspase-independent apoptosis in liver Hep3B cells: role for calcium in signaling oxidative stress-related impairment of mitochondria and relocation of endonuclease G and apoptosis-inducing factor. |journal=Free Radic. Biol. Med. |volume=36 |issue= 12 |pages= 1517–31 |year= 2005 |pmid= 15182854 |doi= 10.1016/j.freeradbiomed.2004.03.020
*cite journal | author=Singh IN, Goody RJ, Dean C, "et al." |title=Apoptotic death of striatal neurons induced by human immunodeficiency virus-1 Tat and gp120: Differential involvement of caspase-3 and endonuclease G. |journal=J. Neurovirol. |volume=10 |issue= 3 |pages= 141–51 |year= 2004 |pmid= 15204919 |doi= 10.1080/13550280490441103
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Kalinowska M, Garncarz W, Pietrowska M, "et al." |title=Regulation of the human apoptotic DNase/RNase endonuclease G: involvement of Hsp70 and ATP. |journal=Apoptosis |volume=10 |issue= 4 |pages= 821–30 |year= 2007 |pmid= 16133872 |doi= 10.1007/s10495-005-0410-9
*cite journal | author=Basnakian AG, Apostolov EO, Yin X, "et al." |title=Endonuclease G promotes cell death of non-invasive human breast cancer cells. |journal=Exp. Cell Res. |volume=312 |issue= 20 |pages= 4139–49 |year= 2007 |pmid= 17046751 |doi= 10.1016/j.yexcr.2006.09.012
*cite journal | author=Whiteman M, Chu SH, Siau JL, "et al." |title=The pro-inflammatory oxidant hypochlorous acid induces Bax-dependent mitochondrial permeabilisation and cell death through AIF-/EndoG-dependent pathways. |journal=Cell. Signal. |volume=19 |issue= 4 |pages= 705–14 |year= 2007 |pmid= 17107772 |doi= 10.1016/j.cellsig.2006.08.019
*cite journal | author=Varecha M, Amrichová J, Zimmermann M, "et al." |title=Bioinformatic and image analyses of the cellular localization of the apoptotic proteins endonuclease G, AIF, and AMID during apoptosis in human cells. |journal=Apoptosis |volume=12 |issue= 7 |pages= 1155–71 |year= 2007 |pmid= 17347867 |doi= 10.1007/s10495-007-0061-0

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