IQGAP2

IQ motif containing GTPase activating protein 2, also known as IQGAP2, is a human gene.cite web | title = Entrez Gene: IQGAP2 IQ motif containing GTPase activating protein 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10788| accessdate = ]

PBB_Summary
section_title =
summary_text = This gene encodes a member of the IQGAP family. The protein contains three IQ domains, one calponin homology domain, one Ras-GAP domain and one WW domain. It interacts with components of the cytoskeleton, with cell adhesion molecules, and with several signaling molecules to regulate cell morphology and motility.cite web | title = Entrez Gene: IQGAP2 IQ motif containing GTPase activating protein 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10788| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=McCallum SJ, Wu WJ, Cerione RA |title=Identification of a putative effector for Cdc42Hs with high sequence similarity to the RasGAP-related protein IQGAP1 and a Cdc42Hs binding partner with similarity to IQGAP2. |journal=J. Biol. Chem. |volume=271 |issue= 36 |pages= 21732–7 |year= 1996 |pmid= 8702968 |doi=
*cite journal | author=Brill S, Li S, Lyman CW, "et al." |title=The Ras GTPase-activating-protein-related human protein IQGAP2 harbors a potential actin binding domain and interacts with calmodulin and Rho family GTPases. |journal=Mol. Cell. Biol. |volume=16 |issue= 9 |pages= 4869–78 |year= 1996 |pmid= 8756646 |doi=
*cite journal | author=Yin H, Morioka H, Towle CA, "et al." |title=Evidence that HAX-1 is an interleukin-1 alpha N-terminal binding protein. |journal=Cytokine |volume=15 |issue= 3 |pages= 122–37 |year= 2001 |pmid= 11554782 |doi= 10.1006/cyto.2001.0891
*cite journal | author=Wennerberg K, Ellerbroek SM, Liu RY, "et al." |title=RhoG signals in parallel with Rac1 and Cdc42. |journal=J. Biol. Chem. |volume=277 |issue= 49 |pages= 47810–7 |year= 2003 |pmid= 12376551 |doi= 10.1074/jbc.M203816200
*cite journal | author=Schmidt VA, Scudder L, Devoe CE, "et al." |title=IQGAP2 functions as a GTP-dependent effector protein in thrombin-induced platelet cytoskeletal reorganization. |journal=Blood |volume=101 |issue= 8 |pages= 3021–8 |year= 2003 |pmid= 12515716 |doi= 10.1182/blood-2002-09-2807
*cite journal | author=Gevaert K, Goethals M, Martens L, "et al." |title=Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides. |journal=Nat. Biotechnol. |volume=21 |issue= 5 |pages= 566–9 |year= 2004 |pmid= 12665801 |doi= 10.1038/nbt810
*cite journal | author=Bouwmeester T, Bauch A, Ruffner H, "et al." |title=A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway. |journal=Nat. Cell Biol. |volume=6 |issue= 2 |pages= 97–105 |year= 2004 |pmid= 14743216 |doi= 10.1038/ncb1086
*cite journal | author=Chew CS, Okamoto CT, Chen X, Qin HY |title=IQGAPs are differentially expressed and regulated in polarized gastric epithelial cells. |journal=Am. J. Physiol. Gastrointest. Liver Physiol. |volume=288 |issue= 2 |pages= G376–87 |year= 2005 |pmid= 15458922 |doi= 10.1152/ajpgi.00290.2004
*cite journal | author=Wang H, Huo R, Xu M, "et al." |title=Cloning and characterization of a novel transcript variant of IQGAP2 in human testis. |journal=DNA Seq. |volume=15 |issue= 5-6 |pages= 319–25 |year= 2005 |pmid= 15621655 |doi= 10.1080/10425170400009012
*cite journal | author=Kimura K, Wakamatsu A, Suzuki Y, "et al." |title=Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. |journal=Genome Res. |volume=16 |issue= 1 |pages= 55–65 |year= 2006 |pmid= 16344560 |doi= 10.1101/gr.4039406
*cite journal | author=Ewing RM, Chu P, Elisma F, "et al." |title=Large-scale mapping of human protein-protein interactions by mass spectrometry. |journal=Mol. Syst. Biol. |volume=3 |issue= |pages= 89 |year= 2007 |pmid= 17353931 |doi= 10.1038/msb4100134

PBB_Controls
update_page = yes
require_manual_inspection = no
update_protein_box = yes
update_summary = yes
update_citations = yes