- CBR3
Carbonyl reductase 3, also known as CBR3, is a human
gene .cite web | title = Entrez Gene: CBR3 carbonyl reductase 3| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=874| accessdate = ]PBB_Summary
section_title =
summary_text = Carbonyl reductase 3 catalyzes the reduction of a large number of biologically and pharmacologically active carbonyl compounds to their corresponding alcohols. The enzyme is classified as a monomeric NADPH-dependent oxidoreductase. CBR3 contains three exons spanning 11.2 kilobases and is closely linked to another carbonyl reductase gene - CBR1.cite web | title = Entrez Gene: CBR3 carbonyl reductase 3| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=874| accessdate = ]References
Further reading
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citations =
*cite journal | author=Wermuth B, Mäder-Heinemann G, Ernst E |title=Cloning and expression of carbonyl reductase from rat testis. |journal=Eur. J. Biochem. |volume=228 |issue= 2 |pages= 473–9 |year= 1995 |pmid= 7705364 |doi=
*cite journal | author=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. |journal=Gene |volume=138 |issue= 1-2 |pages= 171–4 |year= 1994 |pmid= 8125298 |doi=
*cite journal | author=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, "et al." |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library. |journal=Gene |volume=200 |issue= 1-2 |pages= 149–56 |year= 1997 |pmid= 9373149 |doi=
*cite journal | author=Dahmane N, Ghezala GA, Gosset P, "et al." |title=Transcriptional map of the 2.5-Mb CBR-ERG region of chromosome 21 involved in Down syndrome. |journal=Genomics |volume=48 |issue= 1 |pages= 12–23 |year= 1998 |pmid= 9503011 |doi= 10.1006/geno.1997.5146
*cite journal | author=Watanabe K, Sugawara C, Ono A, "et al." |title=Mapping of a novel human carbonyl reductase, CBR3, and ribosomal pseudogenes to human chromosome 21q22.2. |journal=Genomics |volume=52 |issue= 1 |pages= 95–100 |year= 1999 |pmid= 9740676 |doi= 10.1006/geno.1998.5380
*cite journal | author=Ismail E, Al-Mulla F, Tsuchida S, "et al." |title=Carbonyl reductase: a novel metastasis-modulating function. |journal=Cancer Res. |volume=60 |issue= 5 |pages= 1173–6 |year= 2000 |pmid= 10728668 |doi=
*cite journal | author=Hattori M, Fujiyama A, Taylor TD, "et al." |title=The DNA sequence of human chromosome 21. |journal=Nature |volume=405 |issue= 6784 |pages= 311–9 |year= 2000 |pmid= 10830953 |doi= 10.1038/35012518
*cite journal | author=Umemoto M, Yokoyama Y, Sato S, "et al." |title=Carbonyl reductase as a significant predictor of survival and lymph node metastasis in epithelial ovarian cancer. |journal=Br. J. Cancer |volume=85 |issue= 7 |pages= 1032–6 |year= 2001 |pmid= 11592776 |doi= 10.1038/sj.bjc.6692034
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Lakhman SS, Ghosh D, Blanco JG |title=Functional significance of a natural allelic variant of human carbonyl reductase 3 (CBR3). |journal=Drug Metab. Dispos. |volume=33 |issue= 2 |pages= 254–7 |year= 2005 |pmid= 15537833 |doi= 10.1124/dmd.104.002006PBB_Controls
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