- PIGF
Phosphatidylinositol glycan anchor biosynthesis, class F, also known as PIGF, is a human
gene .cite web | title = Entrez Gene: PIGF phosphatidylinositol glycan anchor biosynthesis, class F| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=5281| accessdate = ]PBB_Summary
section_title =
summary_text = This gene encodes a protein that is involved in glycosylphosphatidylinositol (GPI)-anchor biosynthesis. The GPI-anchor is a glycolipid which contains three mannose molecules in its core backbone. The GPI-anchor is found on many blood cells and serves to anchor proteins to the cell surface. This protein and another GPI synthesis protein, PIGO, function in the transfer of ethanolaminephosphate (EtNP) to the third mannose in GPI. At least two alternatively spliced transcripts encoding distinct isoforms have been found for this gene.cite web | title = Entrez Gene: PIGF phosphatidylinositol glycan anchor biosynthesis, class F| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=5281| accessdate = ]References
Further reading
PBB_Further_reading
citations =
*cite journal | author=Kinoshita T, Takahashi M, Inoue N, "et al." |title=Expression cloning of genes for GPI-anchor biosynthesis. |journal=Braz. J. Med. Biol. Res. |volume=27 |issue= 2 |pages= 127–32 |year= 1994 |pmid= 8081220 |doi=
*cite journal | author=Inoue N, Kinoshita T, Orii T, Takeda J |title=Cloning of a human gene, PIG-F, a component of glycosylphosphatidylinositol anchor biosynthesis, by a novel expression cloning strategy. |journal=J. Biol. Chem. |volume=268 |issue= 10 |pages= 6882–5 |year= 1993 |pmid= 8463218 |doi=
*cite journal | author=Ohishi K, Inoue N, Endo Y, "et al." |title=Structure and chromosomal localization of the GPI-anchor synthesis gene PIGF and its pseudogene psi PIGF. |journal=Genomics |volume=29 |issue= 3 |pages= 804–7 |year= 1996 |pmid= 8575782 |doi= 10.1006/geno.1995.9929
*cite journal | author=Hong Y, Maeda Y, Watanabe R, "et al." |title=Requirement of PIG-F and PIG-O for transferring phosphoethanolamine to the third mannose in glycosylphosphatidylinositol. |journal=J. Biol. Chem. |volume=275 |issue= 27 |pages= 20911–9 |year= 2000 |pmid= 10781593 |doi= 10.1074/jbc.M001913200
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Shishioh N, Hong Y, Ohishi K, "et al." |title=GPI7 is the second partner of PIG-F and involved in modification of glycosylphosphatidylinositol. |journal=J. Biol. Chem. |volume=280 |issue= 10 |pages= 9728–34 |year= 2005 |pmid= 15632136 |doi= 10.1074/jbc.M413755200
*cite journal | author=Li W, Shen W, Gill R, "et al." |title=High-resolution quantitative computed tomography demonstrating selective enhancement of medium-size collaterals by placental growth factor-1 in the mouse ischemic hindlimb. |journal=Circulation |volume=113 |issue= 20 |pages= 2445–53 |year= 2006 |pmid= 16702473 |doi= 10.1161/CIRCULATIONAHA.105.586818
*cite journal | author=Yano K, Liaw PC, Mullington JM, "et al." |title=Vascular endothelial growth factor is an important determinant of sepsis morbidity and mortality. |journal=J. Exp. Med. |volume=203 |issue= 6 |pages= 1447–58 |year= 2006 |pmid= 16702604 |doi= 10.1084/jem.20060375
*cite journal | author=Zheng Y, Murakami M, Takahashi H, "et al." |title=Chimeric VEGF-E(NZ7)/PlGF promotes angiogenesis via VEGFR-2 without significant enhancement of vascular permeability and inflammation. |journal=Arterioscler. Thromb. Vasc. Biol. |volume=26 |issue= 9 |pages= 2019–26 |year= 2006 |pmid= 16794222 |doi= 10.1161/01.ATV.0000233336.53574.a1
*cite journal | author=Mohammed KA, Nasreen N, Tepper RS, Antony VB |title=Cyclic stretch induces PlGF expression in bronchial airway epithelial cells via nitric oxide release. |journal=Am. J. Physiol. Lung Cell Mol. Physiol. |volume=292 |issue= 2 |pages= L559–66 |year= 2007 |pmid= 17028267 |doi= 10.1152/ajplung.00075.2006PBB_Controls
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