PIGC

Phosphatidylinositol glycan anchor biosynthesis, class C, also known as PIGC, is a human gene.cite web | title = Entrez Gene: PIGC phosphatidylinositol glycan anchor biosynthesis, class C| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=5279| accessdate = ]

PBB_Summary
section_title =
summary_text = This gene encodes an endoplasmic reticulum associated protein that is involved in glycosylphosphatidylinositol (GPI) lipid anchor biosynthesis. The GPI lipid anchor is a glycolipid found on many blood cells and serves to anchor proteins to the cell surface. The encoded protein is one subunit of the GPI N-acetylglucosaminyl (GlcNAc) transferase that transfers GlcNAc to phosphatidylinositol (PI) on the cytoplasmic side of the endoplasmic reticulum. Two alternatively spliced transcripts that encode the same protein have been found for this gene. A pseudogene on chromosome 11 has also been characterized.cite web | title = Entrez Gene: PIGC phosphatidylinositol glycan anchor biosynthesis, class C| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=5279| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Eisenhaber B, Maurer-Stroh S, Novatchkova M, "et al." |title=Enzymes and auxiliary factors for GPI lipid anchor biosynthesis and post-translational transfer to proteins. |journal=Bioessays |volume=25 |issue= 4 |pages= 367–85 |year= 2003 |pmid= 12655644 |doi= 10.1002/bies.10254
*cite journal | author=Adams MD, Kerlavage AR, Fleischmann RD, "et al." |title=Initial assessment of human gene diversity and expression patterns based upon 83 million nucleotides of cDNA sequence. |journal=Nature |volume=377 |issue= 6547 Suppl |pages= 3–174 |year= 1995 |pmid= 7566098 |doi=
*cite journal | author=Inoue N, Watanabe R, Takeda J, Kinoshita T |title=PIG-C, one of the three human genes involved in the first step of glycosylphosphatidylinositol biosynthesis is a homologue of Saccharomyces cerevisiae GPI2. |journal=Biochem. Biophys. Res. Commun. |volume=226 |issue= 1 |pages= 193–9 |year= 1996 |pmid= 8806613 |doi= 10.1006/bbrc.1996.1332
*cite journal | author=Watanabe R, Kinoshita T, Masaki R, "et al." |title=PIG-A and PIG-H, which participate in glycosylphosphatidylinositol anchor biosynthesis, form a protein complex in the endoplasmic reticulum. |journal=J. Biol. Chem. |volume=271 |issue= 43 |pages= 26868–75 |year= 1996 |pmid= 8900170 |doi=
*cite journal | author=Hong Y, Ohishi K, Inoue N, "et al." |title=Structures and chromosomal localizations of the glycosylphosphatidylinositol synthesis gene PIGC and its pseudogene PIGCP1. |journal=Genomics |volume=44 |issue= 3 |pages= 347–9 |year= 1997 |pmid= 9325057 |doi= 10.1006/geno.1997.4893
*cite journal | author=Watanabe R, Inoue N, Westfall B, "et al." |title=The first step of glycosylphosphatidylinositol biosynthesis is mediated by a complex of PIG-A, PIG-H, PIG-C and GPI1. |journal=EMBO J. |volume=17 |issue= 4 |pages= 877–85 |year= 1998 |pmid= 9463366 |doi= 10.1093/emboj/17.4.877
*cite journal | author=Watanabe R, Murakami Y, Marmor MD, "et al." |title=Initial enzyme for glycosylphosphatidylinositol biosynthesis requires PIG-P and is regulated by DPM2. |journal=EMBO J. |volume=19 |issue= 16 |pages= 4402–11 |year= 2000 |pmid= 10944123 |doi= 10.1093/emboj/19.16.4402
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Rual JF, Venkatesan K, Hao T, "et al." |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209
*cite journal | author=Gregory SG, Barlow KF, McLay KE, "et al." |title=The DNA sequence and biological annotation of human chromosome 1. |journal=Nature |volume=441 |issue= 7091 |pages= 315–21 |year= 2006 |pmid= 16710414 |doi= 10.1038/nature04727

PBB_Controls
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