PFDN4

PFDN4

Prefoldin subunit 4, also known as PFDN4, is a human gene.cite web | title = Entrez Gene: PFDN4 prefoldin subunit 4| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=5203| accessdate = ]

PBB_Summary
section_title =
summary_text = This gene encodes a member of the prefoldin beta subunit family. The encoded protein is one of six subunits of prefoldin, a molecular chaperone complex that binds and stabilizes newly synthesized polypeptides, thereby allowing them to fold correctly. The complex, consisting of two alpha and four beta subunits, forms a double beta barrel assembly with six protruding coiled-coils.cite web | title = Entrez Gene: PFDN4 prefoldin subunit 4| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=5203| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Hartl FU, Hayer-Hartl M |title=Molecular chaperones in the cytosol: from nascent chain to folded protein. |journal=Science |volume=295 |issue= 5561 |pages= 1852–8 |year= 2002 |pmid= 11884745 |doi= 10.1126/science.1068408
*cite journal | author=Iijima M, Kano Y, Nohno T, Namba M |title=Cloning of cDNA with possible transcription factor activity at the G1-S phase transition in human fibroblast cell lines. |journal=Acta Med. Okayama |volume=50 |issue= 2 |pages= 73–7 |year= 1996 |pmid= 8744932 |doi=
*cite journal | author=Vainberg IE, Lewis SA, Rommelaere H, "et al." |title=Prefoldin, a chaperone that delivers unfolded proteins to cytosolic chaperonin. |journal=Cell |volume=93 |issue= 5 |pages= 863–73 |year= 1998 |pmid= 9630229 |doi=
*cite journal | author=Hansen WJ, Cowan NJ, Welch WJ |title=Prefoldin-nascent chain complexes in the folding of cytoskeletal proteins. |journal=J. Cell Biol. |volume=145 |issue= 2 |pages= 265–77 |year= 1999 |pmid= 10209023 |doi=
*cite journal | author=Cowan NJ, Lewis SA |title=A chaperone with a hydrophilic surface. |journal=Nat. Struct. Biol. |volume=6 |issue= 11 |pages= 990–1 |year= 2002 |pmid= 10542082 |doi= 10.1038/14870
*cite journal | author=Collins C, Volik S, Kowbel D, "et al." |title=Comprehensive genome sequence analysis of a breast cancer amplicon. |journal=Genome Res. |volume=11 |issue= 6 |pages= 1034–42 |year= 2001 |pmid= 11381030 |doi= 10.1101/gr.174301
*cite journal | author=Deloukas P, Matthews LH, Ashurst J, "et al." |title=The DNA sequence and comparative analysis of human chromosome 20. |journal=Nature |volume=414 |issue= 6866 |pages= 865–71 |year= 2002 |pmid= 11780052 |doi= 10.1038/414865a
*cite journal | author=Martín-Benito J, Boskovic J, Gómez-Puertas P, "et al." |title=Structure of eukaryotic prefoldin and of its complexes with unfolded actin and the cytosolic chaperonin CCT. |journal=EMBO J. |volume=21 |issue= 23 |pages= 6377–86 |year= 2003 |pmid= 12456645 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Gstaiger M, Luke B, Hess D, "et al." |title=Control of nutrient-sensitive transcription programs by the unconventional prefoldin URI. |journal=Science |volume=302 |issue= 5648 |pages= 1208–12 |year= 2003 |pmid= 14615539 |doi= 10.1126/science.1088401
*cite journal | author=Simons CT, Staes A, Rommelaere H, "et al." |title=Selective contribution of eukaryotic prefoldin subunits to actin and tubulin binding. |journal=J. Biol. Chem. |volume=279 |issue= 6 |pages= 4196–203 |year= 2004 |pmid= 14634002 |doi= 10.1074/jbc.M306053200
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504

PBB_Controls
update_page = yes
require_manual_inspection = no
update_protein_box = yes
update_summary = yes
update_citations = yes


Wikimedia Foundation. 2010.

Игры ⚽ Нужно решить контрольную?

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”