- GAS1
Growth arrest-specific 1, also known as GAS1, is a human
gene .cite web | title = Entrez Gene: GAS1 growth arrest-specific 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=2619| accessdate = ]PBB_Summary
section_title =
summary_text = Growth arrest-specific 1 plays a role in growth suppression. GAS1 blocks entry to S phase and prevents cycling of normal and transformed cells. Gas1 is a putative tumor suppressor gene.cite web | title = Entrez Gene: GAS1 growth arrest-specific 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=2619| accessdate = ]References
Further reading
PBB_Further_reading
citations =
*cite journal | author=Del Sal G, Ruaro ME, Philipson L, Schneider C |title=The growth arrest-specific gene, gas1, is involved in growth suppression. |journal=Cell |volume=70 |issue= 4 |pages= 595–607 |year= 1992 |pmid= 1505026 |doi=
*cite journal | author=Wicking C, Breen M, Negus K, "et al." |title=The human growth-arrest-specific gene GAS1 maps outside the candidate region of the gene for nevoid basal cell carcinoma syndrome. |journal=Cytogenet. Cell Genet. |volume=68 |issue= 1-2 |pages= 119–21 |year= 1994 |pmid= 7956349 |doi=
*cite journal | author=Del Sal G, Collavin L, Ruaro ME, "et al." |title=Structure, function, and chromosome mapping of the growth-suppressing human homologue of the murine gas1 gene. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=91 |issue= 5 |pages= 1848–52 |year= 1994 |pmid= 8127893 |doi=
*cite journal | author=Evdokiou A, Webb GC, Peters GB, "et al." |title=Localization of the human growth arrest-specific gene (GAS1) to chromosome bands 9q21.3-q22, a region frequently deleted in myeloid malignancies. |journal=Genomics |volume=18 |issue= 3 |pages= 731–3 |year= 1994 |pmid= 8307588 |doi=
*cite journal | author=Evdokiou A, Cowled PA |title=Tumor-suppressive activity of the growth arrest-specific gene GAS1 in human tumor cell lines. |journal=Int. J. Cancer |volume=75 |issue= 4 |pages= 568–77 |year= 1998 |pmid= 9466658 |doi=
*cite journal | author=Stebel M, Vatta P, Ruaro ME, "et al." |title=The growth suppressing gas1 product is a GPI-linked protein. |journal=FEBS Lett. |volume=481 |issue= 2 |pages= 152–8 |year= 2000 |pmid= 10996315 |doi=
*cite journal | author=Lee CS, Buttitta L, Fan CM |title=Evidence that the WNT-inducible growth arrest-specific gene 1 encodes an antagonist of sonic hedgehog signaling in the somite. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=98 |issue= 20 |pages= 11347–52 |year= 2001 |pmid= 11572986 |doi= 10.1073/pnas.201418298
*cite journal | author=Baladrón V, Ruiz-Hidalgo MJ, Bonvini E, "et al." |title=The EGF-like homeotic protein dlk affects cell growth and interacts with growth-modulating molecules in the yeast two-hybrid system. |journal=Biochem. Biophys. Res. Commun. |volume=291 |issue= 2 |pages= 193–204 |year= 2002 |pmid= 11846389 |doi= 10.1006/bbrc.2002.6431
*cite journal | author=Mellström B, Ceña V, Lamas M, "et al." |title=Gas1 is induced during and participates in excitotoxic neuronal death. |journal=Mol. Cell. Neurosci. |volume=19 |issue= 3 |pages= 417–29 |year= 2002 |pmid= 11906213 |doi= 10.1006/mcne.2001.1092
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Xu Y, Kulkosky J, Acheampong E, "et al." |title=HIV-1-mediated apoptosis of neuronal cells: Proximal molecular mechanisms of HIV-1-induced encephalopathy. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 18 |pages= 7070–5 |year= 2004 |pmid= 15103018 |doi= 10.1073/pnas.0304859101
*cite journal | author=Cabrera JR, Sanchez-Pulido L, Rojas AM, "et al." |title=Gas1 is related to the glial cell-derived neurotrophic factor family receptors alpha and regulates Ret signaling. |journal=J. Biol. Chem. |volume=281 |issue= 20 |pages= 14330–9 |year= 2006 |pmid= 16551639 |doi= 10.1074/jbc.M509572200PBB_Controls
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