RGS8

Regulator of G-protein signalling 8, also known as RGS8, is a human gene.cite web | title = Entrez Gene: RGS8 regulator of G-protein signalling 8| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=85397| accessdate = ]

PBB_Summary
section_title =
summary_text = This gene is a member of the regulator of G protein signaling (RGS) family and encodes a protein with a single RGS domain. Regulator of G protein signaling (RGS) proteins are regulatory and structural components of G protein-coupled receptor complexes. They accelerate transit through the cycle of GTP binding and hydrolysis to GDP, thereby terminating signal transduction, but paradoxically, also accelerate receptor-stimulated activation.cite web | title = Entrez Gene: RGS8 regulator of G-protein signalling 8| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=85397| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Sood R, Bonner TI, Makalowska I, "et al." |title=Cloning and characterization of 13 novel transcripts and the human RGS8 gene from the 1q25 region encompassing the hereditary prostate cancer (HPC1) locus. |journal=Genomics |volume=73 |issue= 2 |pages= 211–22 |year= 2001 |pmid= 11318611 |doi= 10.1006/geno.2001.6500
*cite journal | author=Harrington JJ, Sherf B, Rundlett S, "et al." |title=Creation of genome-wide protein expression libraries using random activation of gene expression. |journal=Nat. Biotechnol. |volume=19 |issue= 5 |pages= 440–5 |year= 2001 |pmid= 11329013 |doi= 10.1038/88107
*cite journal | author=Sierra DA, Gilbert DJ, Householder D, "et al." |title=Evolution of the regulators of G-protein signaling multigene family in mouse and human. |journal=Genomics |volume=79 |issue= 2 |pages= 177–85 |year= 2002 |pmid= 11829488 |doi= 10.1006/geno.2002.6693
*cite journal | author=Saitoh O, Murata Y, Odagiri M, "et al." |title=Alternative splicing of RGS8 gene determines inhibitory function of receptor type-specific Gq signaling. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 15 |pages= 10138–43 |year= 2002 |pmid= 12110731 |doi= 10.1073/pnas.152085999
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Masuho I, Itoh M, Itoh H, Saitoh O |title=The mechanism of membrane-translocation of regulator of G-protein signaling (RGS) 8 induced by Galpha expression. |journal=J. Neurochem. |volume=88 |issue= 1 |pages= 161–8 |year= 2004 |pmid= 14675160 |doi=
*cite journal | author=Larminie C, Murdock P, Walhin JP, "et al." |title=Selective expression of regulators of G-protein signaling (RGS) in the human central nervous system. |journal=Brain Res. Mol. Brain Res. |volume=122 |issue= 1 |pages= 24–34 |year= 2004 |pmid= 14992813 |doi= 10.1016/j.molbrainres.2003.11.014
*cite journal | author=Saitoh O, Yoshihiro K |title=Biochemical and electrophysiological analyses of RGS8 function. |journal=Meth. Enzymol. |volume=390 |issue= |pages= 129–48 |year= 2005 |pmid= 15488175 |doi= 10.1016/S0076-6879(04)90009-2
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Benians A, Nobles M, Tinker A |title=Participation of RGS8 in the ternary complex of agonist, receptor and G-protein. |journal=Biochem. Soc. Trans. |volume=32 |issue= Pt 6 |pages= 1045–7 |year= 2005 |pmid= 15506959 |doi= 10.1042/BST0321045
*cite journal | author=Benians A, Nobles M, Hosny S, Tinker A |title=Regulators of G-protein signaling form a quaternary complex with the agonist, receptor, and G-protein. A novel explanation for the acceleration of signaling activation kinetics. |journal=J. Biol. Chem. |volume=280 |issue= 14 |pages= 13383–94 |year= 2005 |pmid= 15677457 |doi= 10.1074/jbc.M410163200
*cite journal | author=Gregory SG, Barlow KF, McLay KE, "et al." |title=The DNA sequence and biological annotation of human chromosome 1. |journal=Nature |volume=441 |issue= 7091 |pages= 315–21 |year= 2006 |pmid= 16710414 |doi= 10.1038/nature04727

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