PIP4K2B

Phosphatidylinositol-4-phosphate 5-kinase, type II, beta, also known as PIP5K2B, is a human gene.cite web | title = Entrez Gene: PIP5K2B phosphatidylinositol-4-phosphate 5-kinase, type II, beta| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=8396| accessdate = ]

PBB_Summary
section_title =
summary_text = The protein encoded by this gene catalyzes the phosphorylation of phosphatidylinositol-4-phosphate on the fifth hydroxyl of the myo-inositol ring to form phosphatidylinositol-4,5-bisphosphate. This gene is a member of the phosphatidylinositol-4-phosphate 5-kinase family. The encoded protein sequence does not show similarity to other kinases, but the protein does exhibit kinase activity. Additionally, the encoded protein interacts with p55 TNF receptor.cite web | title = Entrez Gene: PIP5K2B phosphatidylinositol-4-phosphate 5-kinase, type II, beta| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=8396| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Niiro H, Clark EA |title=Branches of the B cell antigen receptor pathway are directed by protein conduits Bam32 and Carma1. |journal=Immunity |volume=19 |issue= 5 |pages= 637–40 |year= 2003 |pmid= 14614850 |doi=
*cite journal | author=Carpenter CL |title=Btk-dependent regulation of phosphoinositide synthesis. |journal=Biochem. Soc. Trans. |volume=32 |issue= Pt 2 |pages= 326–9 |year= 2004 |pmid= 15046600 |doi= 10.1042/
*cite journal | author=Castellino AM, Parker GJ, Boronenkov IV, "et al." |title=A novel interaction between the juxtamembrane region of the p55 tumor necrosis factor receptor and phosphatidylinositol-4-phosphate 5-kinase. |journal=J. Biol. Chem. |volume=272 |issue= 9 |pages= 5861–70 |year= 1997 |pmid= 9038203 |doi=
*cite journal | author=Rameh LE, Tolias KF, Duckworth BC, Cantley LC |title=A new pathway for synthesis of phosphatidylinositol-4,5-bisphosphate. |journal=Nature |volume=390 |issue= 6656 |pages= 192–6 |year= 1997 |pmid= 9367159 |doi= 10.1038/36621
*cite journal | author=Rao VD, Misra S, Boronenkov IV, "et al." |title=Structure of type IIbeta phosphatidylinositol phosphate kinase: a protein kinase fold flattened for interfacial phosphorylation. |journal=Cell |volume=94 |issue= 6 |pages= 829–39 |year= 1998 |pmid= 9753329 |doi=
*cite journal | author=Boronenkov IV, Loijens JC, Umeda M, Anderson RA |title=Phosphoinositide signaling pathways in nuclei are associated with nuclear speckles containing pre-mRNA processing factors. |journal=Mol. Biol. Cell |volume=9 |issue= 12 |pages= 3547–60 |year= 1999 |pmid= 9843587 |doi=
*cite journal | author=Kutsenko AS, Gizatullin RZ, Al-Amin AN, "et al." |title=NotI flanking sequences: a tool for gene discovery and verification of the human genome. |journal=Nucleic Acids Res. |volume=30 |issue= 14 |pages= 3163–70 |year= 2002 |pmid= 12136098 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Luoh SW, Venkatesan N, Tripathi R |title=Overexpression of the amplified Pip4k2beta gene from 17q11-12 in breast cancer cells confers proliferation advantage. |journal=Oncogene |volume=23 |issue= 7 |pages= 1354–63 |year= 2004 |pmid= 14691457 |doi= 10.1038/sj.onc.1207251
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Rual JF, Venkatesan K, Hao T, "et al." |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209
*cite journal | author=Lim J, Hao T, Shaw C, "et al." |title=A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration. |journal=Cell |volume=125 |issue= 4 |pages= 801–14 |year= 2006 |pmid= 16713569 |doi= 10.1016/j.cell.2006.03.032
*cite journal | author=Richardson JP, Wang M, Clarke JH, "et al." |title=Genomic tagging of endogenous type IIbeta phosphatidylinositol 5-phosphate 4-kinase in DT40 cells reveals a nuclear localisation. |journal=Cell. Signal. |volume=19 |issue= 6 |pages= 1309–14 |year= 2007 |pmid= 17303380 |doi= 10.1016/j.cellsig.2007.01.010

PBB_Controls
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