- GPAM
Glycerol-3-phosphate acyltransferase, mitochondrial, also known as GPAM, is a human
gene .cite web | title = Entrez Gene: GPAM glycerol-3-phosphate acyltransferase, mitochondrial| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=57678| accessdate = ]PBB_Summary
section_title =
summary_text = Glycerol-3-phosphate acyltransferase (GPAT; EC 2.3.1.15), which catalyzes the initial and committing step in glycerolipid biosynthesis, is predicted to play a pivotal role in the regulation of cellular triacylglycerol and phospholipid levels. Two mammalian forms of GPAT have been identified on the basis of localization to either the endoplasmic reticulum or mitochondria. [supplied by OMIM] cite web | title = Entrez Gene: GPAM glycerol-3-phosphate acyltransferase, mitochondrial| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=57678| accessdate = ]References
Further reading
PBB_Further_reading
citations =
*cite journal | author=Skorve J, Ruyter B, Rustan AC, "et al." |title=Effect of 3- and 4-thia-substituted fatty acids on glycerolipid metabolism and mitochondrial beta-oxidation in rat liver. |journal=Biochem. Pharmacol. |volume=40 |issue= 9 |pages= 2005–12 |year= 1990 |pmid= 2242030 |doi=
*cite journal | author=Thomas PD, Poznansky MJ |title=Lipid peroxidation inactivates rat liver microsomal glycerol-3-phosphate acyl transferase. Effect of iron and copper salts and carbon tetrachloride. |journal=J. Biol. Chem. |volume=265 |issue= 5 |pages= 2684–91 |year= 1990 |pmid= 2303421 |doi=
*cite journal | author=Yet SF, Lee S, Hahm YT, Sul HS |title=Expression and identification of p90 as the murine mitochondrial glycerol-3-phosphate acyltransferase. |journal=Biochemistry |volume=32 |issue= 36 |pages= 9486–91 |year= 1993 |pmid= 8369314 |doi=
*cite journal | author=Welch CL, Xia YR, Edwards PA, "et al." |title=Assignment of Gpam to distal mouse chromosome 19 by linkage analysis. |journal=Mamm. Genome |volume=9 |issue= 1 |pages= 93 |year= 1998 |pmid= 9434961 |doi=
*cite journal | author=Nagase T, Kikuno R, Nakayama M, "et al." |title=Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. |journal=DNA Res. |volume=7 |issue= 4 |pages= 273–81 |year= 2001 |pmid= 10997877 |doi=
*cite journal | author=Hartley JL, Temple GF, Brasch MA |title=DNA cloning using in vitro site-specific recombination. |journal=Genome Res. |volume=10 |issue= 11 |pages= 1788–95 |year= 2001 |pmid= 11076863 |doi=
*cite journal | author=Wiemann S, Weil B, Wellenreuther R, "et al." |title=Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. |journal=Genome Res. |volume=11 |issue= 3 |pages= 422–35 |year= 2001 |pmid= 11230166 |doi= 10.1101/gr.154701
*cite journal | author=Igal RA, Wang S, Gonzalez-Baró M, Coleman RA |title=Mitochondrial glycerol phosphate acyltransferase directs the incorporation of exogenous fatty acids into triacylglycerol. |journal=J. Biol. Chem. |volume=276 |issue= 45 |pages= 42205–12 |year= 2001 |pmid= 11546763 |doi= 10.1074/jbc.M103386200
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Deloukas P, Earthrowl ME, Grafham DV, "et al." |title=The DNA sequence and comparative analysis of human chromosome 10. |journal=Nature |volume=429 |issue= 6990 |pages= 375–81 |year= 2004 |pmid= 15164054 |doi= 10.1038/nature02462
*cite journal | author=Wiemann S, Arlt D, Huber W, "et al." |title=From ORFeome to biology: a functional genomics pipeline. |journal=Genome Res. |volume=14 |issue= 10B |pages= 2136–44 |year= 2004 |pmid= 15489336 |doi= 10.1101/gr.2576704
*cite journal | author=Mehrle A, Rosenfelder H, Schupp I, "et al." |title=The LIFEdb database in 2006. |journal=Nucleic Acids Res. |volume=34 |issue= Database issue |pages= D415–8 |year= 2006 |pmid= 16381901 |doi= 10.1093/nar/gkj139PBB_Controls
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