PPEF1

Protein phosphatase, EF-hand calcium binding domain 1, also known as PPEF1, is a human gene.cite web | title = Entrez Gene: PPEF1 protein phosphatase, EF-hand calcium binding domain 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=5475| accessdate = ]

PBB_Summary
section_title =
summary_text = This gene encodes a member of the serine/threonine protein phosphatase with EF-hand motif family. The protein contains a protein phosphatase catalytic domain, and at least two EF-hand calcium-binding motifs in its C terminus. Although its substrate(s) is unknown, the encoded protein has been suggested to play a role in specific sensory neuron function and/or development. This gene shares high sequence similarity with the Drosophila retinal degeneration C (rdgC) gene. Several alternatively spliced transcript variants, each encoding a distinct isoform, have been described.cite web | title = Entrez Gene: PPEF1 protein phosphatase, EF-hand calcium binding domain 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=5475| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Herzig S, Neumann J |title=Effects of serine/threonine protein phosphatases on ion channels in excitable membranes. |journal=Physiol. Rev. |volume=80 |issue= 1 |pages= 173–210 |year= 2000 |pmid= 10617768 |doi=
*cite journal | author=Montini E, Rugarli EI, Van de Vosse E, "et al." |title=A novel human serine-threonine phosphatase related to the Drosophila retinal degeneration C (rdgC) gene is selectively expressed in sensory neurons of neural crest origin. |journal=Hum. Mol. Genet. |volume=6 |issue= 7 |pages= 1137–45 |year= 1997 |pmid= 9215685 |doi=
*cite journal | author=Sherman PM, Sun H, Macke JP, "et al." |title=Identification and characterization of a conserved family of protein serine/threonine phosphatases homologous to Drosophila retinal degeneration C. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=94 |issue= 21 |pages= 11639–44 |year= 1997 |pmid= 9326663 |doi=
*cite journal | author=Huang X, Honkanen RE |title=Molecular cloning, expression, and characterization of a novel human serine/threonine protein phosphatase, PP7, that is homologous to Drosophila retinal degeneration C gene product (rdgC). |journal=J. Biol. Chem. |volume=273 |issue= 3 |pages= 1462–8 |year= 1998 |pmid= 9430683 |doi=
*cite journal | author=Ramulu P, Kennedy M, Xiong WH, "et al." |title=Normal light response, photoreceptor integrity, and rhodopsin dephosphorylation in mice lacking both protein phosphatases with EF hands (PPEF-1 and PPEF-2). |journal=Mol. Cell. Biol. |volume=21 |issue= 24 |pages= 8605–14 |year= 2001 |pmid= 11713293 |doi= 10.1128/MCB.21.24.8605-8614.2001
*cite journal | author=Kutuzov MA, Solov'eva OV, Andreeva AV, Bennett N |title=Protein Ser/Thr phosphatases PPEF interact with calmodulin. |journal=Biochem. Biophys. Res. Commun. |volume=293 |issue= 3 |pages= 1047–52 |year= 2002 |pmid= 12051765 |doi= 10.1016/S0006-291X(02)00338-8
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Gevaert K, Goethals M, Martens L, "et al." |title=Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides. |journal=Nat. Biotechnol. |volume=21 |issue= 5 |pages= 566–9 |year= 2004 |pmid= 12665801 |doi= 10.1038/nbt810
*cite journal | author=Hillman RT, Green RE, Brenner SE |title=An unappreciated role for RNA surveillance. |journal=Genome Biol. |volume=5 |issue= 2 |pages= R8 |year= 2005 |pmid= 14759258 |doi= 10.1186/gb-2004-5-2-r8
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Ross MT, Grafham DV, Coffey AJ, "et al." |title=The DNA sequence of the human X chromosome. |journal=Nature |volume=434 |issue= 7031 |pages= 325–37 |year= 2005 |pmid= 15772651 |doi= 10.1038/nature03440
*cite journal | author=Rual JF, Venkatesan K, Hao T, "et al." |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209

PBB_Controls
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require_manual_inspection = no
update_protein_box = yes
update_summary = yes
update_citations = yes