CYP2S1

Cytochrome P450, family 2, subfamily S, polypeptide 1, also known as CYP2S1, is a human gene.cite web | title = Entrez Gene: CYP2S1 cytochrome P450, family 2, subfamily S, polypeptide 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=29785| accessdate = ]

PBB_Summary
section_title =
summary_text = This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. In rodents, the homologous protein has been shown to metabolize certain carcinogens; however, the specific function of the human protein has not been determined.cite web | title = Entrez Gene: CYP2S1 cytochrome P450, family 2, subfamily S, polypeptide 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=29785| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Adams MD, Kerlavage AR, Fleischmann RD, "et al." |title=Initial assessment of human gene diversity and expression patterns based upon 83 million nucleotides of cDNA sequence. |journal=Nature |volume=377 |issue= 6547 Suppl |pages= 3–174 |year= 1995 |pmid= 7566098 |doi=
*cite journal | author=Rylander T, Neve EP, Ingelman-Sundberg M, Oscarson M |title=Identification and tissue distribution of the novel human cytochrome P450 2S1 (CYP2S1). |journal=Biochem. Biophys. Res. Commun. |volume=281 |issue= 2 |pages= 529–35 |year= 2001 |pmid= 11181079 |doi= 10.1006/bbrc.2001.4390
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Smith G, Wolf CR, Deeni YY, "et al." |title=Cutaneous expression of cytochrome P450 CYP2S1: individuality in regulation by therapeutic agents for psoriasis and other skin diseases. |journal=Lancet |volume=361 |issue= 9366 |pages= 1336–43 |year= 2003 |pmid= 12711469 |doi=
*cite journal | author=Saito S, Iida A, Sekine A, "et al." |title=Catalog of 680 variations among eight cytochrome p450 ( CYP) genes, nine esterase genes, and two other genes in the Japanese population. |journal=J. Hum. Genet. |volume=48 |issue= 5 |pages= 249–70 |year= 2003 |pmid= 12721789 |doi= 10.1007/s10038-003-0021-7
*cite journal | author=Clark HF, Gurney AL, Abaya E, "et al." |title=The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. |journal=Genome Res. |volume=13 |issue= 10 |pages= 2265–70 |year= 2003 |pmid= 12975309 |doi= 10.1101/gr.1293003
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Rivera SP, Wang F, Saarikoski ST, "et al." |title=A novel promoter element containing multiple overlapping xenobiotic and hypoxia response elements mediates induction of cytochrome P4502S1 by both dioxin and hypoxia. |journal=J. Biol. Chem. |volume=282 |issue= 15 |pages= 10881–93 |year= 2007 |pmid= 17277313 |doi= 10.1074/jbc.M609617200
*cite journal | author=Marek CJ, Tucker SJ, Koruth M, "et al." |title=Expression of CYP2S1 in human hepatic stellate cells. |journal=FEBS Lett. |volume=581 |issue= 4 |pages= 781–6 |year= 2007 |pmid= 17280660 |doi= 10.1016/j.febslet.2007.01.056
*cite journal | author=Hanzawa Y, Sasaki T, Hiratsuka M, "et al." |title=Three novel single nucleotide polymorphisms (SNPs) of CYP2S1 gene in Japanese individuals. |journal=Drug Metab. Pharmacokinet. |volume=22 |issue= 2 |pages= 136–40 |year= 2007 |pmid= 17495422 |doi=
*cite journal | author=Jang YJ, Cha EY, Kim WY, "et al." |title=CYP2S1 gene polymorphisms in a Korean population. |journal=Therapeutic drug monitoring |volume=29 |issue= 3 |pages= 292–8 |year= 2007 |pmid= 17529885 |doi= 10.1097/FTD.0b013e318058a4e0

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