CYP2A

Cytochrome P450, family 2, subfamily A, also known as CYP2A, is a human gene.cite web | title = Entrez Gene: CYP2A cytochrome P450, family 2, subfamily A| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=1546| accessdate = ]

PBB_Summary
section_title =
summary_text = The cytochrome P450 superfamily of enzymes are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The CYP2 gene cluster on chromosome 19q13.2 includes several genes and pseudogenes from the CYP2A, CYP2B, and CYP2F subfamilies.cite web | title = Entrez Gene: CYP2A cytochrome P450, family 2, subfamily A| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=1546| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Fernandez-Salguero P, Gonzalez FJ |title=The CYP2A gene subfamily: species differences, regulation, catalytic activities and role in chemical carcinogenesis. |journal=Pharmacogenetics |volume=5 Spec No |issue= |pages= S123–8 |year= 1995 |pmid= 7581481 |doi=
*cite journal | author=Smith G, Stubbins MJ, Harries LW, Wolf CR |title=Molecular genetics of the human cytochrome P450 monooxygenase superfamily. |journal=Xenobiotica |volume=28 |issue= 12 |pages= 1129–65 |year= 1999 |pmid= 9890157 |doi=
*cite journal | author=Raunio H, Rautio A, Pelkonen O |title=The CYP2A subfamily: function, expression and genetic polymorphism. |journal=IARC Sci. Publ. |volume= |issue= 148 |pages= 197–207 |year= 1999 |pmid= 10493259 |doi=
*cite journal | author=Nelson DR, Zeldin DC, Hoffman SM, "et al." |title=Comparison of cytochrome P450 (CYP) genes from the mouse and human genomes, including nomenclature recommendations for genes, pseudogenes and alternative-splice variants. |journal=Pharmacogenetics |volume=14 |issue= 1 |pages= 1–18 |year= 2004 |pmid= 15128046 |doi=
*cite journal | author=Nhamburo PT, Kimura S, McBride OW, "et al." |title=The human CYP2F gene subfamily: identification of a cDNA encoding a new cytochrome P450, cDNA-directed expression, and chromosome mapping. |journal=Biochemistry |volume=29 |issue= 23 |pages= 5491–9 |year= 1990 |pmid= 1974816 |doi=
*cite journal | author=Miles JS, McLaren AW, Gonzalez FJ, Wolf CR |title=Alternative splicing in the human cytochrome P450IIB6 gene: use of a cryptic exon within intron 3 and splice acceptor site within exon 4. |journal=Nucleic Acids Res. |volume=18 |issue= 1 |pages= 189 |year= 1990 |pmid= 2308828 |doi=
*cite journal | author=Yamano S, Nhamburo PT, Aoyama T, "et al." |title=cDNA cloning and sequence and cDNA-directed expression of human P450 IIB1: identification of a normal and two variant cDNAs derived from the CYP2B locus on chromosome 19 and differential expression of the IIB mRNAs in human liver. |journal=Biochemistry |volume=28 |issue= 18 |pages= 7340–8 |year= 1990 |pmid= 2573390 |doi=
*cite journal | author=Miles JS, Bickmore W, Brook JD, "et al." |title=Close linkage of the human cytochrome P450IIA and P450IIB gene subfamilies: implications for the assignment of substrate specificity. |journal=Nucleic Acids Res. |volume=17 |issue= 8 |pages= 2907–17 |year= 1989 |pmid= 2726448 |doi=
*cite journal | author=Miles JS, McLaren AW, Wolf CR |title=Alternative splicing in the human cytochrome P450IIB6 gene generates a high level of aberrant messages. |journal=Nucleic Acids Res. |volume=17 |issue= 20 |pages= 8241–55 |year= 1989 |pmid= 2813061 |doi=
*cite journal | author=Fernandez-Salguero P, Hoffman SM, Cholerton S, "et al." |title=A genetic polymorphism in coumarin 7-hydroxylation: sequence of the human CYP2A genes and identification of variant CYP2A6 alleles. |journal=Am. J. Hum. Genet. |volume=57 |issue= 3 |pages= 651–60 |year= 1995 |pmid= 7668294 |doi=
*cite journal | author=Trask B, Fertitta A, Christensen M, "et al." |title=Fluorescence in situ hybridization mapping of human chromosome 19: cytogenetic band location of 540 cosmids and 70 genes or DNA markers. |journal=Genomics |volume=15 |issue= 1 |pages= 133–45 |year= 1993 |pmid= 8432525 |doi=
*cite journal | author=Hoffman SM, Fernandez-Salguero P, Gonzalez FJ, Mohrenweiser HW |title=Organization and evolution of the cytochrome P450 CYP2A-2B-2F subfamily gene cluster on human chromosome 19. |journal=J. Mol. Evol. |volume=41 |issue= 6 |pages= 894–900 |year= 1996 |pmid= 8587134 |doi=
*cite journal | author=Rylander T, Neve EP, Ingelman-Sundberg M, Oscarson M |title=Identification and tissue distribution of the novel human cytochrome P450 2S1 (CYP2S1). |journal=Biochem. Biophys. Res. Commun. |volume=281 |issue= 2 |pages= 529–35 |year= 2001 |pmid= 11181079 |doi= 10.1006/bbrc.2001.4390

PBB_Controls
update_page = yes
require_manual_inspection = no
update_protein_box = yes
update_summary = yes
update_citations = yes