ABCB6

ATP-binding cassette, sub-family B (MDR/TAP), member 6, also known as ABCB6, is a human gene.cite web | title = Entrez Gene: ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10058| accessdate = ]

PBB_Summary
section_title =
summary_text = The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This half-transporter likely plays a role in mitochondrial function. Localized to 2q26, this gene is considered a candidate gene for lethal neonatal metabolic syndrome, a disorder of mitochondrial function.cite web | title = Entrez Gene: ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10058| accessdate = ]

ee also

* ATP-binding cassette transporter

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Paterson JK, Shukla S, Black CM, "et al." |title=Human ABCB6 localizes to both the outer mitochondrial membrane and the plasma membrane. |journal=Biochemistry |volume=46 |issue= 33 |pages= 9443–52 |year= 2007 |pmid= 17661442 |doi= 10.1021/bi700015m
*cite journal | author=Krishnamurthy PC, Du G, Fukuda Y, "et al." |title=Identification of a mammalian mitochondrial porphyrin transporter. |journal=Nature |volume=443 |issue= 7111 |pages= 586–9 |year= 2006 |pmid= 17006453 |doi= 10.1038/nature05125
*cite journal | author=Kurashima-Ito K, Ikeya T, Senbongi H, "et al." |title=Heteronuclear multidimensional NMR and homology modelling studies of the C-terminal nucleotide-binding domain of the human mitochondrial ABC transporter ABCB6. |journal=J. Biomol. NMR |volume=35 |issue= 1 |pages= 53–71 |year= 2006 |pmid= 16791740 |doi= 10.1007/s10858-006-9000-6
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Visapää I, Fellman V, Lanyi L, Peltonen L |title=ABCB6 (MTABC3) excluded as the causative gene for the growth retardation syndrome with aminoaciduria, cholestasis, iron overload, and lactacidosis. |journal=Am. J. Med. Genet. |volume=109 |issue= 3 |pages= 202–5 |year= 2002 |pmid= 11977179 |doi= 10.1002/ajmg.10331
*cite journal | author=Emadi-Konjin HP, Zhang H, Anandan V, "et al." |title=Isolation of a genomic clone containing the promoter region of the human ATP binding cassette (ABC) transporter, ABCB6. |journal=Biochim. Biophys. Acta |volume=1574 |issue= 2 |pages= 117–30 |year= 2002 |pmid= 11955620 |doi=
*cite journal | author=Mitsuhashi N, Miki T, Senbongi H, "et al." |title=MTABC3, a novel mitochondrial ATP-binding cassette protein involved in iron homeostasis. |journal=J. Biol. Chem. |volume=275 |issue= 23 |pages= 17536–40 |year= 2000 |pmid= 10837493 |doi=
*cite journal | author=Furuya KN, Bradley G, Sun D, "et al." |title=Identification of a new P-glycoprotein-like ATP-binding cassette transporter gene that is overexpressed during hepatocarcinogenesis. |journal=Cancer Res. |volume=57 |issue= 17 |pages= 3708–16 |year= 1997 |pmid= 9288777 |doi=
*cite journal | author=Yu W, Andersson B, Worley KC, "et al." |title=Large-scale concatenation cDNA sequencing. |journal=Genome Res. |volume=7 |issue= 4 |pages= 353–8 |year= 1997 |pmid= 9110174 |doi=
*cite journal | author=Allikmets R, Gerrard B, Hutchinson A, Dean M |title=Characterization of the human ABC superfamily: isolation and mapping of 21 new genes using the expressed sequence tags database. |journal=Hum. Mol. Genet. |volume=5 |issue= 10 |pages= 1649–55 |year= 1997 |pmid= 8894702 |doi=
*cite journal | author=Andersson B, Wentland MA, Ricafrente JY, "et al." |title=A "double adaptor" method for improved shotgun library construction. |journal=Anal. Biochem. |volume=236 |issue= 1 |pages= 107–13 |year= 1996 |pmid= 8619474 |doi= 10.1006/abio.1996.0138

External links

*

PBB_Controls
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