MAML1

Mastermind-like 1 (Drosophila), also known as MAML1, is a human gene.cite web | title = Entrez Gene: MAML1 mastermind-like 1 (Drosophila)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9794| accessdate = ]

PBB_Summary
section_title =
summary_text = This protein is the human homolog of mastermind, a Drosophila protein that plays a role in the Notch signaling pathway involved in cell-fate determination. There is in vitro evidence that the human homolog forms a complex with the intracellular portion of human Notch receptors and can increase expression of a Notch-induced gene. This evidence supports its proposed function as a transcriptional co-activator in the Notch signaling pathway.cite web | title = Entrez Gene: MAML1 mastermind-like 1 (Drosophila)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9794| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Alves-Guerra MC, Ronchini C, Capobianco AJ |title=Mastermind-like 1 Is a specific coactivator of beta-catenin transcription activation and is essential for colon carcinoma cell survival. |journal=Cancer Res. |volume=67 |issue= 18 |pages= 8690–8 |year= 2007 |pmid= 17875709 |doi= 10.1158/0008-5472.CAN-07-1720
*cite journal | author=Zhao Y, Katzman RB, Delmolino LM, "et al." |title=The notch regulator MAML1 interacts with p53 and functions as a coactivator. |journal=J. Biol. Chem. |volume=282 |issue= 16 |pages= 11969–81 |year= 2007 |pmid= 17317671 |doi= 10.1074/jbc.M608974200
*cite journal | author=Nam Y, Sliz P, Song L, "et al." |title=Structural basis for cooperativity in recruitment of MAML coactivators to Notch transcription complexes. |journal=Cell |volume=124 |issue= 5 |pages= 973–83 |year= 2006 |pmid= 16530044 |doi= 10.1016/j.cell.2005.12.037
*cite journal | author=Fryer CJ, White JB, Jones KA |title=Mastermind recruits CycC:CDK8 to phosphorylate the Notch ICD and coordinate activation with turnover. |journal=Mol. Cell |volume=16 |issue= 4 |pages= 509–20 |year= 2005 |pmid= 15546612 |doi= 10.1016/j.molcel.2004.10.014
*cite journal | author=Nam Y, Weng AP, Aster JC, Blacklow SC |title=Structural requirements for assembly of the CSL.intracellular Notch1.Mastermind-like 1 transcriptional activation complex. |journal=J. Biol. Chem. |volume=278 |issue= 23 |pages= 21232–9 |year= 2003 |pmid= 12644465 |doi= 10.1074/jbc.M301567200
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Wallberg AE, Pedersen K, Lendahl U, Roeder RG |title=p300 and PCAF act cooperatively to mediate transcriptional activation from chromatin templates by notch intracellular domains in vitro. |journal=Mol. Cell. Biol. |volume=22 |issue= 22 |pages= 7812–9 |year= 2002 |pmid= 12391150 |doi=
*cite journal | author=Lin SE, Oyama T, Nagase T, "et al." |title=Identification of new human mastermind proteins defines a family that consists of positive regulators for notch signaling. |journal=J. Biol. Chem. |volume=277 |issue= 52 |pages= 50612–20 |year= 2003 |pmid= 12386158 |doi= 10.1074/jbc.M209529200
*cite journal | author=Fryer CJ, Lamar E, Turbachova I, "et al." |title=Mastermind mediates chromatin-specific transcription and turnover of the Notch enhancer complex. |journal=Genes Dev. |volume=16 |issue= 11 |pages= 1397–411 |year= 2002 |pmid= 12050117 |doi= 10.1101/gad.991602
*cite journal | author=Wu G, Lyapina S, Das I, "et al." |title=SEL-10 is an inhibitor of notch signaling that targets notch for ubiquitin-mediated protein degradation. |journal=Mol. Cell. Biol. |volume=21 |issue= 21 |pages= 7403–15 |year= 2001 |pmid= 11585921 |doi= 10.1128/MCB.21.21.7403-7415.2001
*cite journal | author=Kitagawa M, Oyama T, Kawashima T, "et al." |title=A human protein with sequence similarity to Drosophila mastermind coordinates the nuclear form of notch and a CSL protein to build a transcriptional activator complex on target promoters. |journal=Mol. Cell. Biol. |volume=21 |issue= 13 |pages= 4337–46 |year= 2001 |pmid= 11390662 |doi= 10.1128/MCB.21.13.4337-4346.2001
*cite journal | author=Wu L, Aster JC, Blacklow SC, "et al." |title=MAML1, a human homologue of Drosophila mastermind, is a transcriptional co-activator for NOTCH receptors. |journal=Nat. Genet. |volume=26 |issue= 4 |pages= 484–9 |year= 2001 |pmid= 11101851 |doi= 10.1038/82644
*cite journal | author=Nagase T, Seki N, Ishikawa K, "et al." |title=Prediction of the coding sequences of unidentified human genes. V. The coding sequences of 40 new genes (KIAA0161-KIAA0200) deduced by analysis of cDNA clones from human cell line KG-1 (supplement). |journal=DNA Res. |volume=3 |issue= 1 |pages= 43–53 |year= 1996 |pmid= 8724853 |doi=
*cite journal | author=Nagase T, Seki N, Ishikawa K, "et al." |title=Prediction of the coding sequences of unidentified human genes. V. The coding sequences of 40 new genes (KIAA0161-KIAA0200) deduced by analysis of cDNA clones from human cell line KG-1. |journal=DNA Res. |volume=3 |issue= 1 |pages= 17–24 |year= 1996 |pmid= 8724849 |doi=

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