ENTPD2

Ectonucleoside triphosphate diphosphohydrolase 2, also known as ENTPD2, is a human gene.cite web | title = Entrez Gene: ENTPD2 ectonucleoside triphosphate diphosphohydrolase 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=954| accessdate = ]

PBB_Summary
section_title =
summary_text = The protein encoded by this gene is the type 2 enzyme of the ecto-nucleoside triphosphate diphosphohydrolase family (E-NTPDase). E-NTPDases are a family of ecto-nucleosidases that hydrolyze 5'-triphosphates. This ecto-ATPase is an integral membrane protein. Alternative splicing of this gene results in multiple transcript variants.cite web | title = Entrez Gene: ENTPD2 ectonucleoside triphosphate diphosphohydrolase 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=954| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Javed R, Yarimizu K, Pelletier N, "et al." |title=Mutagenesis of lysine 62, asparagine 64, and conserved region 1 reduces the activity of human ecto-ATPase (NTPDase 2). |journal=Biochemistry |volume=46 |issue= 22 |pages= 6617–27 |year= 2007 |pmid= 17489562 |doi= 10.1021/bi700036e
*cite journal | author=Mukasa T, Lee Y, Knowles AF |title=Either the carboxyl- or the amino-terminal region of the human ecto-ATPase (E-NTPDase 2) confers detergent and temperature sensitivity to the chicken ecto-ATP-diphosphohydrolase (E-NTPDase 8). |journal=Biochemistry |volume=44 |issue= 33 |pages= 11160–70 |year= 2005 |pmid= 16101300 |doi= 10.1021/bi050019k
*cite journal | author=Jhandier MN, Kruglov EA, Lavoie EG, "et al." |title=Portal fibroblasts regulate the proliferation of bile duct epithelia via expression of NTPDase2. |journal=J. Biol. Chem. |volume=280 |issue= 24 |pages= 22986–92 |year= 2005 |pmid= 15799977 |doi= 10.1074/jbc.M412371200
*cite journal | author=Dranoff JA, Kruglov EA, Toure J, "et al." |title=Ectonucleotidase NTPDase2 is selectively down-regulated in biliary cirrhosis. |journal=J. Investig. Med. |volume=52 |issue= 7 |pages= 475–82 |year= 2005 |pmid= 15651265 |doi=
*cite journal | author=Alvarado-Castillo C, Harden TK, Boyer JL |title=Regulation of P2Y1 receptor-mediated signaling by the ectonucleoside triphosphate diphosphohydrolase isozymes NTPDase1 and NTPDase2. |journal=Mol. Pharmacol. |volume=67 |issue= 1 |pages= 114–22 |year= 2005 |pmid= 15496502 |doi= 10.1124/mol.104.006908
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Knowles AF, Chiang WC |title=Enzymatic and transcriptional regulation of human ecto-ATPase/E-NTPDase 2. |journal=Arch. Biochem. Biophys. |volume=418 |issue= 2 |pages= 217–27 |year= 2003 |pmid= 14522593 |doi=
*cite journal | author=Mateo J, Kreda S, Henry CE, "et al." |title=Requirement of Cys399 for processing of the human ecto-ATPase (NTPDase2) and its implications for determination of the activities of splice variants of the enzyme. |journal=J. Biol. Chem. |volume=278 |issue= 41 |pages= 39960–8 |year= 2003 |pmid= 12888562 |doi= 10.1074/jbc.M307854200
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Grinthal A, Guidotti G |title=Transmembrane domains confer different substrate specificities and adenosine diphosphate hydrolysis mechanisms on CD39, CD39L1, and chimeras. |journal=Biochemistry |volume=41 |issue= 6 |pages= 1947–56 |year= 2002 |pmid= 11827541 |doi=
*cite journal | author=Suzuki H, Fukunishi Y, Kagawa I, "et al." |title=Protein-protein interaction panel using mouse full-length cDNAs. |journal=Genome Res. |volume=11 |issue= 10 |pages= 1758–65 |year= 2001 |pmid= 11591653 |doi= 10.1101/gr.180101
*cite journal | author=Mateo J, Harden TK, Boyer JL |title=Functional expression of a cDNA encoding a human ecto-ATPase. |journal=Br. J. Pharmacol. |volume=128 |issue= 2 |pages= 396–402 |year= 2000 |pmid= 10510450 |doi= 10.1038/sj.bjp.0702805
*cite journal | author=Chadwick BP, Frischauf AM |title=Cloning and mapping of a human and mouse gene with homology to ecto-ATPase genes. |journal=Mamm. Genome |volume=8 |issue= 9 |pages= 668–72 |year= 1997 |pmid= 9271669 |doi=

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