Thrifty phenotype

Thrifty phenotype

It has been suggested that in poor nutritional conditions, a pregnant female can modify the development of her unborn child such that it will be prepared for survival in an environment in which resources are likely to be short, resulting in a thrifty phenotype (Hales & Barker, 1992 [Hales, C.N., & Barker, D.J. (1992). Type 2 (non-insulin-dependent) diabetes mellitus: the thrifty phenotype hypothesis. "Diabetologia". 35: 595-601. [http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=1644236&dopt=Citation PubMed] ] ). Individuals with a thrifty phenotype will have "a smaller body size, a lowered metabolic rate and a reduced level of behavioural activity… adaptations to an environment that is chronically short of food" (Bateson & Martin, 1999 [Bateson, P., & Martin, P. (1999). "Design for a life: How behaviour develops". London: Jonathan Cape. ISBN 0-224-05064-8, pp. 110-111] ). Those with a thrifty phenotype who actually develop in an affluent environment may be more prone to metabolic disorders, such as obesity and type II diabetes, whereas those who have received a positive maternal forecast will be adapted to good conditions and therefore better able to cope with rich diets. This idea, which is also known as the Barker hypothesis (Barker, 1992 [Barker, D. J. P. (Ed.). (1992). "Fetal and infant origins of adult disease". London: BMJ Books. ISBN 0-7279-0743-3] ), is now widely (if not universally) accepted and is a source of grave concern for societies undergoing a transition from sparse to better nutrition (Robinson, 2001 [Robinson, R. (2001). The fetal origins of adult disease. No longer just a hypothesis and may be critically important in south Asia [http://bmj.bmjjournals.com/cgi/content/full/322/7283/375 Editorial] . "British Medical Journal". 322: 375-376.] ).

ee also

*Evolutionary developmental psychology
*Evolutionary physiology
*Trivers-Willard hypothesis
*Thrifty gene hypothesis

References

External links

* [http://bmj.bmjjournals.com/cgi/collection/barker_hypothesis British Medical Journal Topic Collections: Barker Hypothesis]
* [http://scholar.google.com/scholar?hl=en&lr=&safe=off&q=%22thrifty+phenotype%22&btnG=Search Google Scholar]


Wikimedia Foundation. 2010.

Игры ⚽ Поможем написать реферат

Look at other dictionaries:

  • Thrifty — is the name of several companies * Thrifty Foods * Thrifty Drug Stores (now Rite Aid) * Thrifty Rent A Car (part of Dollar Thrifty Automotive Group)It is also a name given to a type of phenotype * Thrifty phenotype See also * Thrift …   Wikipedia

  • Life history theory — is an analytical framework widely used in animal and human biology, psychology, and evolutionary anthropology which postulates that many of the physiological traits and behaviors of individuals may be best understood in terms of the key… …   Wikipedia

  • Evolutionary neuropathology — is an approach to understanding neurological and neurodegenerative diseases in terms of adaptation to environment, natural history and evolutionary medicine. Conceptually, it overlaps with a number of areas in theoretical biology, such as… …   Wikipedia

  • Obesity — Cla …   Wikipedia

  • Phenotypic plasticity — The ability of an organism with a given genotype to change its phenotype in response to changes in the environment is called phenotypic plasticity. [cite journal |author=Price TD, Qvarnström A, Irwin DE |title=The role of phenotypic plasticity in …   Wikipedia

  • Pima — The Akimel O odham or Pima are a group of American Indians living in an area consisting of what is now central and southern Arizona (USA) and Sonora (Mexico). The name means river people . They are closely related to the Tohono O odham (meaning… …   Wikipedia

  • Evolutionary physiology — is the study of physiological evolution, which is to say, the manner in which the functional characteristics of individuals in a population of organisms have responded to selection across multiple generations during the history of the… …   Wikipedia

  • Human physiology — is the science of the mechanical, physical, and biochemical functions of humans in good health, their organs, and the cells of which they are composed. The principal level of focus of physiology is at the level of organs and systems. Most aspects …   Wikipedia

  • Barker's hypothesis — The Barker Hypothesis is named after David J. P. Barker a researcher at the University of Southampton who published the theory in 1997. Barker, D.J.P. (1997). Maternal Nutrition, Fetal Nutrition, and Disease in Later Life . Nutrition , 13 , pg.… …   Wikipedia

  • Drifty gene hypothesis — The “”Drifty gene hypothesis”” [1] was proposed by the British biologist John Speakman as an alternative to the thrifty gene hypothesis originally proposed by James V Neel in 1962 [2] Speakman’s critique of the thrifty gene hypothesis is based on …   Wikipedia

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”