CACYBP

Calcyclin binding protein, also known as CACYBP, is a human gene.cite web | title = Entrez Gene: CACYBP calcyclin binding protein| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=27101| accessdate = ]

PBB_Summary
section_title =
summary_text = The protein encoded by this gene is a calcyclin binding protein. It may be involved in calcium-dependent ubiquitination and subsequent proteosomal degradation of target proteins. It probably serves as a molecular bridge in ubiquitin E3 complexes and participates in the ubiquitin-mediated degradation of beta-catenin. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene.cite web | title = Entrez Gene: CACYBP calcyclin binding protein| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=27101| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Matsuzawa SI, Reed JC |title=Siah-1, SIP, and Ebi collaborate in a novel pathway for beta-catenin degradation linked to p53 responses. |journal=Mol. Cell |volume=7 |issue= 5 |pages= 915–26 |year= 2001 |pmid= 11389839 |doi=
*cite journal | author=Filipek A, Jastrzebska B, Nowotny M, "et al." |title=Ca2+-dependent translocation of the calcyclin-binding protein in neurons and neuroblastoma NB-2a cells. |journal=J. Biol. Chem. |volume=277 |issue= 23 |pages= 21103–9 |year= 2002 |pmid= 11927578 |doi= 10.1074/jbc.M111010200
*cite journal | author=Liu WX, Wu J, Zhao Z, "et al." |title= [Cloning and expression of human calcyclin binding protein (hCacyBP) gene] |journal=Sheng Wu Hua Xue Yu Sheng Wu Wu Li Xue Bao |volume=34 |issue= 2 |pages= 181–6 |year= 2003 |pmid= 12006993 |doi=
*cite journal | author=Filipek A, Jastrzebska B, Nowotny M, Kuznicki J |title=CacyBP/SIP, a calcyclin and Siah-1-interacting protein, binds EF-hand proteins of the S100 family. |journal=J. Biol. Chem. |volume=277 |issue= 32 |pages= 28848–52 |year= 2002 |pmid= 12042313 |doi= 10.1074/jbc.M203602200
*cite journal | author=Matsuzawa S, Li C, Ni CZ, "et al." |title=Structural analysis of Siah1 and its interactions with Siah-interacting protein (SIP). |journal=J. Biol. Chem. |volume=278 |issue= 3 |pages= 1837–40 |year= 2003 |pmid= 12421809 |doi= 10.1074/jbc.M210263200
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Wu J, Tan X, Peng X, "et al." |title=Translocation and phosphorylation of calcyclin binding protein during retinoic acid-induced neuronal differentiation of neuroblastoma SH-SY5Y cells. |journal=J. Biochem. Mol. Biol. |volume=36 |issue= 4 |pages= 354–8 |year= 2004 |pmid= 12895292 |doi=
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Santelli E, Leone M, Li C, "et al." |title=Structural analysis of Siah1-Siah-interacting protein interactions and insights into the assembly of an E3 ligase multiprotein complex. |journal=J. Biol. Chem. |volume=280 |issue= 40 |pages= 34278–87 |year= 2005 |pmid= 16085652 |doi= 10.1074/jbc.M506707200
*cite journal | author=Rual JF, Venkatesan K, Hao T, "et al." |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209
*cite journal | author=Ewing RM, Chu P, Elisma F, "et al." |title=Large-scale mapping of human protein-protein interactions by mass spectrometry. |journal=Mol. Syst. Biol. |volume=3 |issue= |pages= 89 |year= 2007 |pmid= 17353931 |doi= 10.1038/msb4100134
*cite journal | author=Sun S, Ning X, Liu J, "et al." |title=Overexpressed CacyBP/SIP leads to the suppression of growth in renal cell carcinoma. |journal=Biochem. Biophys. Res. Commun. |volume=356 |issue= 4 |pages= 864–71 |year= 2007 |pmid= 17400182 |doi= 10.1016/j.bbrc.2007.03.080

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