FKBP2

FK506 binding protein 2, 13kDa, also known as FKBP2, is a human gene.cite web | title = Entrez Gene: FKBP2 FK506 binding protein 2, 13kDa| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=2286| accessdate = ]

PBB_Summary
section_title =
summary_text = The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It is thought to function as an ER chaperone and may also act as a component of membrane cytoskeletal scaffolds. This gene has two alternatively spliced transcript variants that encode the same isoform. Multiple polyadenylation sites have been described for this gene, but the full length nature of this gene has not been determined.cite web | title = Entrez Gene: FKBP2 FK506 binding protein 2, 13kDa| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=2286| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=DiLella AG, Hawkins A, Craig RJ, "et al." |title=Chromosomal band assignments of the genes encoding human FKBP12 and FKBP13. |journal=Biochem. Biophys. Res. Commun. |volume=189 |issue= 2 |pages= 819–23 |year= 1993 |pmid= 1281998 |doi=
*cite journal | author=Jin YJ, Albers MW, Lane WS, "et al." |title=Molecular cloning of a membrane-associated human FK506- and rapamycin-binding protein, FKBP-13. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=88 |issue= 15 |pages= 6677–81 |year= 1991 |pmid= 1713687 |doi=
*cite journal | author=Hendrickson BA, Zhang W, Craig RJ, "et al." |title=Structural organization of the genes encoding human and murine FK506-binding protein (FKBP) 13 and comparison to FKBP1. |journal=Gene |volume=134 |issue= 2 |pages= 271–5 |year= 1994 |pmid= 7505249 |doi=
*cite journal | author=Bush KT, Hendrickson BA, Nigam SK |title=Induction of the FK506-binding protein, FKBP13, under conditions which misfold proteins in the endoplasmic reticulum. |journal=Biochem. J. |volume=303 ( Pt 3) |issue= |pages= 705–8 |year= 1994 |pmid= 7526846 |doi=
*cite journal | author=Nigam SK, Jin YJ, Jin MJ, "et al." |title=Localization of the FK506-binding protein, FKBP 13, to the lumen of the endoplasmic reticulum. |journal=Biochem. J. |volume=294 ( Pt 2) |issue= |pages= 511–5 |year= 1993 |pmid= 8373365 |doi=
*cite journal | author=Walensky LD, Gascard P, Fields ME, "et al." |title=The 13-kD FK506 binding protein, FKBP13, interacts with a novel homologue of the erythrocyte membrane cytoskeletal protein 4.1. |journal=J. Cell Biol. |volume=141 |issue= 1 |pages= 143–53 |year= 1998 |pmid= 9531554 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Padilla PI, Chang MJ, Pacheco-Rodriguez G, "et al." |title=Interaction of FK506-binding protein 13 with brefeldin A-inhibited guanine nucleotide-exchange protein 1 (BIG1): effects of FK506. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=100 |issue= 5 |pages= 2322–7 |year= 2003 |pmid= 12606707 |doi= 10.1073/pnas.2628047100
*cite journal | author=Willingham S, Outeiro TF, DeVit MJ, "et al." |title=Yeast genes that enhance the toxicity of a mutant huntingtin fragment or alpha-synuclein. |journal=Science |volume=302 |issue= 5651 |pages= 1769–72 |year= 2003 |pmid= 14657499 |doi= 10.1126/science.1090389
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Won J, Kim M, Yi YW, "et al." |title=A magnetic nanoprobe technology for detecting molecular interactions in live cells. |journal=Science |volume=309 |issue= 5731 |pages= 121–5 |year= 2005 |pmid= 15994554 |doi= 10.1126/science.1112869
*cite journal | author=Rual JF, Venkatesan K, Hao T, "et al." |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209
*cite journal | author=Lim J, Hao T, Shaw C, "et al." |title=A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration. |journal=Cell |volume=125 |issue= 4 |pages= 801–14 |year= 2006 |pmid= 16713569 |doi= 10.1016/j.cell.2006.03.032

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