AKAP11

A kinase (PRKA) anchor protein 11, also known as AKAP11, is a human gene.cite web | title = Entrez Gene: AKAP11 A kinase (PRKA) anchor protein 11| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=11215| accessdate = ]

PBB_Summary
section_title =
summary_text = The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein is expressed at high levels throughout spermatogenesis and in mature sperm. It binds the RI and RII subunits of PKA in testis. It may serve a function in cell cycle control of both somatic cells and germ cells in addition to its putative role in spermatogenesis and sperm function.cite web | title = Entrez Gene: AKAP11 A kinase (PRKA) anchor protein 11| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=11215| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Lester LB, Scott JD |title=Anchoring and scaffold proteins for kinases and phosphatases. |journal=Recent Prog. Horm. Res. |volume=52 |issue= |pages= 409–29; discussion 429–30 |year= 1997 |pmid= 9238861 |doi=
*cite journal | author=Michel JJ, Scott JD |title=AKAP mediated signal transduction. |journal=Annu. Rev. Pharmacol. Toxicol. |volume=42 |issue= |pages= 235–57 |year= 2002 |pmid= 11807172 |doi= 10.1146/annurev.pharmtox.42.083101.135801
*cite journal | author=Nakajima D, Okazaki N, Yamakawa H, "et al." |title=Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones. |journal=DNA Res. |volume=9 |issue= 3 |pages= 99–106 |year= 2003 |pmid= 12168954 |doi=
*cite journal | author=Lester LB, Coghlan VM, Nauert B, Scott JD |title=Cloning and characterization of a novel A-kinase anchoring protein. AKAP 220, association with testicular peroxisomes. |journal=J. Biol. Chem. |volume=271 |issue= 16 |pages= 9460–5 |year= 1996 |pmid= 8621616 |doi=
*cite journal | author=Ishikawa K, Nagase T, Suyama M, "et al." |title=Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. |journal=DNA Res. |volume=5 |issue= 3 |pages= 169–76 |year= 1998 |pmid= 9734811 |doi=
*cite journal | author=Schillace RV, Scott JD |title=Association of the type 1 protein phosphatase PP1 with the A-kinase anchoring protein AKAP220. |journal=Curr. Biol. |volume=9 |issue= 6 |pages= 321–4 |year= 1999 |pmid= 10209101 |doi=
*cite journal | author=Reinton N, Collas P, Haugen TB, "et al." |title=Localization of a novel human A-kinase-anchoring protein, hAKAP220, during spermatogenesis. |journal=Dev. Biol. |volume=223 |issue= 1 |pages= 194–204 |year= 2000 |pmid= 10864471 |doi= 10.1006/dbio.2000.9725
*cite journal | author=Schillace RV, Voltz JW, Sim AT, "et al." |title=Multiple interactions within the AKAP220 signaling complex contribute to protein phosphatase 1 regulation. |journal=J. Biol. Chem. |volume=276 |issue= 15 |pages= 12128–34 |year= 2001 |pmid= 11152471 |doi= 10.1074/jbc.M010398200
*cite journal | author=Schillace RV, Andrews SF, Liberty GA, "et al." |title=Identification and characterization of myeloid translocation gene 16b as a novel a kinase anchoring protein in T lymphocytes. |journal=J. Immunol. |volume=168 |issue= 4 |pages= 1590–9 |year= 2002 |pmid= 11823486 |doi=
*cite journal | author=Tanji C, Yamamoto H, Yorioka N, "et al." |title=A-kinase anchoring protein AKAP220 binds to glycogen synthase kinase-3beta (GSK-3beta ) and mediates protein kinase A-dependent inhibition of GSK-3beta. |journal=J. Biol. Chem. |volume=277 |issue= 40 |pages= 36955–61 |year= 2002 |pmid= 12147701 |doi= 10.1074/jbc.M206210200
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Dunham A, Matthews LH, Burton J, "et al." |title=The DNA sequence and analysis of human chromosome 13. |journal=Nature |volume=428 |issue= 6982 |pages= 522–8 |year= 2004 |pmid= 15057823 |doi= 10.1038/nature02379
*cite journal | author=Ewing RM, Chu P, Elisma F, "et al." |title=Large-scale mapping of human protein-protein interactions by mass spectrometry. |journal=Mol. Syst. Biol. |volume=3 |issue= |pages= 89 |year= 2007 |pmid= 17353931 |doi= 10.1038/msb4100134

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