CPLX1

Complexin 1, also known as CPLX1, is a human gene.cite web | title = Entrez Gene: CPLX1 complexin 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10815| accessdate = ]

PBB_Summary
section_title =
summary_text = Proteins encoded by the complexin/synaphin gene family are cytosolic proteins that function in synaptic vesicle exocytosis. These proteins bind syntaxin, part of the SNAP receptor. The protein product of this gene binds to the SNAP receptor complex and disrupts it, allowing transmitter release.cite web | title = Entrez Gene: CPLX1 complexin 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10815| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Abe T |title= [The mechanism of neurotransmitter release: role of synaphin/complexin in synaptic vesicle exocytosis] |journal=Tanpakushitsu Kakusan Koso |volume=47 |issue= 7 |pages= 794–800 |year= 2002 |pmid= 12058476 |doi=
*cite journal | author=McMahon HT, Missler M, Li C, Südhof TC |title=Complexins: cytosolic proteins that regulate SNAP receptor function. |journal=Cell |volume=83 |issue= 1 |pages= 111–9 |year= 1995 |pmid= 7553862 |doi=
*cite journal | author=Ishizuka T, Saisu H, Odani S, Abe T |title=Synaphin: a protein associated with the docking/fusion complex in presynaptic terminals. |journal=Biochem. Biophys. Res. Commun. |volume=213 |issue= 3 |pages= 1107–14 |year= 1995 |pmid= 7654227 |doi= 10.1006/bbrc.1995.2241
*cite journal | author=Harrison PJ, Eastwood SL |title=Preferential involvement of excitatory neurons in medial temporal lobe in schizophrenia. |journal=Lancet |volume=352 |issue= 9141 |pages= 1669–73 |year= 1998 |pmid= 9853440 |doi=
*cite journal | author=Ishizuka T, Saisu H, Odani S, "et al." |title=Distinct regional distribution in the brain of messenger RNAs for the two isoforms of synaphin associated with the docking/fusion complex. |journal=Neuroscience |volume=88 |issue= 1 |pages= 295–306 |year= 1999 |pmid= 10051208 |doi=
*cite journal | author=Eastwood SL, Cotter D, Harrison PJ |title=Cerebellar synaptic protein expression in schizophrenia. |journal=Neuroscience |volume=105 |issue= 1 |pages= 219–29 |year= 2001 |pmid= 11483314 |doi=
*cite journal | author=Chen X, Tomchick DR, Kovrigin E, "et al." |title=Three-dimensional structure of the complexin/SNARE complex. |journal=Neuron |volume=33 |issue= 3 |pages= 397–409 |year= 2002 |pmid= 11832227 |doi=
*cite journal | author=Sawada K, Young CE, Barr AM, "et al." |title=Altered immunoreactivity of complexin protein in prefrontal cortex in severe mental illness. |journal=Mol. Psychiatry |volume=7 |issue= 5 |pages= 484–92 |year= 2002 |pmid= 12082566 |doi= 10.1038/sj.mp.4000978
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Basso M, Giraudo S, Corpillo D, "et al." |title=Proteome analysis of human substantia nigra in Parkinson's disease. |journal=Proteomics |volume=4 |issue= 12 |pages= 3943–52 |year= 2005 |pmid= 15526345 |doi= 10.1002/pmic.200400848
*cite journal | author=Rual JF, Venkatesan K, Hao T, "et al." |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209
*cite journal | author=Giraudo CG, Eng WS, Melia TJ, Rothman JE |title=A clamping mechanism involved in SNARE-dependent exocytosis. |journal=Science |volume=313 |issue= 5787 |pages= 676–80 |year= 2006 |pmid= 16794037 |doi= 10.1126/science.1129450

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