HBXIP

Hepatitis B virus x interacting protein, also known as HBXIP, is a human gene.cite web | title = Entrez Gene: HBXIP hepatitis B virus x interacting protein| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10542| accessdate = ]

PBB_Summary
section_title =
summary_text = This gene encodes a protein that specifically complexes with the C-terminus of hepatitis B virus X protein (HBx). The function of this protein is to negatively regulate HBx activity and thus to alter the replication life cycle of the virus.cite web | title = Entrez Gene: HBXIP hepatitis B virus x interacting protein| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10542| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Melegari M, Scaglioni PP, Wands JR |title=Cloning and characterization of a novel hepatitis B virus x binding protein that inhibits viral replication. |journal=J. Virol. |volume=72 |issue= 3 |pages= 1737–43 |year= 1998 |pmid= 9499022 |doi=
*cite journal | author=Shamay M, Barak O, Doitsh G, "et al." |title=Hepatitis B virus pX interacts with HBXAP, a PHD finger protein to coactivate transcription. |journal=J. Biol. Chem. |volume=277 |issue= 12 |pages= 9982–8 |year= 2002 |pmid= 11788598 |doi= 10.1074/jbc.M111354200
*cite journal | author=Li Y, Lu YY |title=Applying a highly specific and reproducible cDNA RDA method to clone garlic up-regulated genes in human gastric cancer cells. |journal=World J. Gastroenterol. |volume=8 |issue= 2 |pages= 213–6 |year= 2002 |pmid= 11925594 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Marusawa H, Matsuzawa S, Welsh K, "et al." |title=HBXIP functions as a cofactor of survivin in apoptosis suppression. |journal=EMBO J. |volume=22 |issue= 11 |pages= 2729–40 |year= 2003 |pmid= 12773388 |doi= 10.1093/emboj/cdg263
*cite journal | author=Kong HJ, Park MJ, Hong S, "et al." |title=Hepatitis B virus X protein regulates transactivation activity and protein stability of the cancer-amplified transcription coactivator ASC-2. |journal=Hepatology |volume=38 |issue= 5 |pages= 1258–66 |year= 2003 |pmid= 14578865 |doi= 10.1053/jhep.2003.50451
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Lee SH, Park SG, Lim SO, Jung G |title=The hepatitis B virus X protein up-regulates lymphotoxin alpha expression in hepatocytes. |journal=Biochim. Biophys. Acta |volume=1741 |issue= 1-2 |pages= 75–84 |year= 2005 |pmid= 15955450 |doi= 10.1016/j.bbadis.2004.10.004
*cite journal | author=Lee AT, Ren J, Wong ET, "et al." |title=The hepatitis B virus X protein sensitizes HepG2 cells to UV light-induced DNA damage. |journal=J. Biol. Chem. |volume=280 |issue= 39 |pages= 33525–35 |year= 2005 |pmid= 16055925 |doi= 10.1074/jbc.M506628200
*cite journal | author=Stelzl U, Worm U, Lalowski M, "et al." |title=A human protein-protein interaction network: a resource for annotating the proteome. |journal=Cell |volume=122 |issue= 6 |pages= 957–68 |year= 2005 |pmid= 16169070 |doi= 10.1016/j.cell.2005.08.029
*cite journal | author=Minczuk M, Mroczek S, Pawlak SD, Stepien PP |title=Human ATP-dependent RNA/DNA helicase hSuv3p interacts with the cofactor of survivin HBXIP. |journal=FEBS J. |volume=272 |issue= 19 |pages= 5008–19 |year= 2005 |pmid= 16176273 |doi= 10.1111/j.1742-4658.2005.04910.x
*cite journal | author=Muroyama R, Kato N, Yoshida H, "et al." |title=Nucleotide change of codon 38 in the X gene of hepatitis B virus genotype C is associated with an increased risk of hepatocellular carcinoma. |journal=J. Hepatol. |volume=45 |issue= 6 |pages= 805–12 |year= 2007 |pmid= 17050029 |doi= 10.1016/j.jhep.2006.07.025
*cite journal | author=Chen J, Siddiqui A |title=Hepatitis B virus X protein stimulates the mitochondrial translocation of Raf-1 via oxidative stress. |journal=J. Virol. |volume=81 |issue= 12 |pages= 6757–60 |year= 2007 |pmid= 17428866 |doi= 10.1128/JVI.00172-07

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