KLRG1

Killer cell lectin-like receptor subfamily G, member 1, also known as KLRG1, is a human gene.cite web | title = Entrez Gene: KLRG1 killer cell lectin-like receptor subfamily G, member 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10219| accessdate = ]

PBB_Summary
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summary_text = Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. The protein encoded by this gene belongs to the killer cell lectin-like receptor (KLR) family, which is a group of transmembrane proteins preferentially expressed in NK cells. Studies in mice suggested that the expression of this gene may be regulated by MHC class I molecules. Alternatively spliced transcript variants have been reported, but their full-length natures have not yet been determined.cite web | title = Entrez Gene: KLRG1 killer cell lectin-like receptor subfamily G, member 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10219| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Ortega E, Schneider H, Pecht I |title=Possible interactions between the Fc epsilon receptor and a novel mast cell function-associated antigen. |journal=Int. Immunol. |volume=3 |issue= 4 |pages= 333–42 |year= 1991 |pmid= 1831652 |doi=
*cite journal | author=Lamers MB, Lamont AG, Williams DH |title=Human MAFA has alternatively spliced variants. |journal=Biochim. Biophys. Acta |volume=1399 |issue= 2-3 |pages= 209–12 |year= 1998 |pmid= 9765598 |doi=
*cite journal | author=Butcher S, Arney KL, Cook GP |title=MAFA-L, an ITIM-containing receptor encoded by the human NK cell gene complex and expressed by basophils and NK cells. |journal=Eur. J. Immunol. |volume=28 |issue= 11 |pages= 3755–62 |year= 1998 |pmid= 9842918 |doi=
*cite journal | author=Hanke T, Corral L, Vance RE, Raulet DH |title=2F1 antigen, the mouse homolog of the rat "mast cell function-associated antigen", is a lectin-like type II transmembrane receptor expressed by natural killer cells. |journal=Eur. J. Immunol. |volume=28 |issue= 12 |pages= 4409–17 |year= 1999 |pmid= 9862378 |doi=
*cite journal | author=Voehringer D, Koschella M, Pircher H |title=Lack of proliferative capacity of human effector and memory T cells expressing killer cell lectinlike receptor G1 (KLRG1). |journal=Blood |volume=100 |issue= 10 |pages= 3698–702 |year= 2003 |pmid= 12393723 |doi= 10.1182/blood-2002-02-0657
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Matsuoka TA, Artner I, Henderson E, "et al." |title=The MafA transcription factor appears to be responsible for tissue-specific expression of insulin. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 9 |pages= 2930–3 |year= 2004 |pmid= 14973194 |doi= 10.1073/pnas.0306233101
*cite journal | author=Marcolino I, Przybylski GK, Koschella M, "et al." |title=Frequent expression of the natural killer cell receptor KLRG1 in human cord blood T cells: correlation with replicative history. |journal=Eur. J. Immunol. |volume=34 |issue= 10 |pages= 2672–80 |year= 2004 |pmid= 15368283 |doi= 10.1002/eji.200425282
*cite journal | author=Ibegbu CC, Xu YX, Harris W, "et al." |title=Expression of killer cell lectin-like receptor G1 on antigen-specific human CD8+ T lymphocytes during active, latent, and resolved infection and its relation with CD57. |journal=J. Immunol. |volume=174 |issue= 10 |pages= 6088–94 |year= 2005 |pmid= 15879103 |doi=
*cite journal | author=Thimme R, Appay V, Koschella M, "et al." |title=Increased expression of the NK cell receptor KLRG1 by virus-specific CD8 T cells during persistent antigen stimulation. |journal=J. Virol. |volume=79 |issue= 18 |pages= 12112–6 |year= 2005 |pmid= 16140789 |doi= 10.1128/JVI.79.18.12112-12116.2005
*cite journal | author=Rual JF, Venkatesan K, Hao T, "et al." |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209
*cite journal | author=Ito M, Maruyama T, Saito N, "et al." |title=Killer cell lectin-like receptor G1 binds three members of the classical cadherin family to inhibit NK cell cytotoxicity. |journal=J. Exp. Med. |volume=203 |issue= 2 |pages= 289–95 |year= 2006 |pmid= 16461340 |doi= 10.1084/jem.20051986
*cite journal | author=Bengsch B, Spangenberg HC, Kersting N, "et al." |title=Analysis of CD127 and KLRG1 expression on hepatitis C virus-specific CD8+ T cells reveals the existence of different memory T-cell subsets in the peripheral blood and liver. |journal=J. Virol. |volume=81 |issue= 2 |pages= 945–53 |year= 2007 |pmid= 17079288 |doi= 10.1128/JVI.01354-06
*cite journal | author=Schwartzkopff S, Gründemann C, Schweier O, "et al." |title=Tumor-associated E-cadherin mutations affect binding to the killer cell lectin-like receptor G1 in humans. |journal=J. Immunol. |volume=179 |issue= 2 |pages= 1022–9 |year= 2007 |pmid= 17617594 |doi=

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