VAPA

VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa, also known as VAPA, is a human gene.cite web | title = Entrez Gene: VAPA VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9218| accessdate = ]

PBB_Summary
section_title =
summary_text = The protein encoded by this gene is a type IV membrane protein. It is present in the plasma membrane and intracellular vesicles. It may also be associated with the cytoskeleton. This protein may function in vesicle trafficking, membrane fusion, protein complex assembly and cell motility. Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified.cite web | title = Entrez Gene: VAPA VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9218| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Weir ML, Klip A, Trimble WS |title=Identification of a human homologue of the vesicle-associated membrane protein (VAMP)-associated protein of 33 kDa (VAP-33): a broadly expressed protein that binds to VAMP. |journal=Biochem. J. |volume=333 ( Pt 2) |issue= |pages= 247–51 |year= 1998 |pmid= 9657962 |doi=
*cite journal | author=Nishimura Y, Hayashi M, Inada H, Tanaka T |title=Molecular cloning and characterization of mammalian homologues of vesicle-associated membrane protein-associated (VAMP-associated) proteins. |journal=Biochem. Biophys. Res. Commun. |volume=254 |issue= 1 |pages= 21–6 |year= 1999 |pmid= 9920726 |doi= 10.1006/bbrc.1998.9876
*cite journal | author=Lapierre LA, Tuma PL, Navarre J, "et al." |title=VAP-33 localizes to both an intracellular vesicle population and with occludin at the tight junction. |journal=J. Cell. Sci. |volume=112 ( Pt 21) |issue= |pages= 3723–32 |year= 1999 |pmid= 10523508 |doi=
*cite journal | author=Tu H, Gao L, Shi ST, "et al." |title=Hepatitis C virus RNA polymerase and NS5A complex with a SNARE-like protein. |journal=Virology |volume=263 |issue= 1 |pages= 30–41 |year= 1999 |pmid= 10544080 |doi= 10.1006/viro.1999.9893
*cite journal | author=Weir ML, Xie H, Klip A, Trimble WS |title=VAP-A binds promiscuously to both v- and tSNAREs. |journal=Biochem. Biophys. Res. Commun. |volume=286 |issue= 3 |pages= 616–21 |year= 2001 |pmid= 11511104 |doi= 10.1006/bbrc.2001.5437
*cite journal | author=Wyles JP, McMaster CR, Ridgway ND |title=Vesicle-associated membrane protein-associated protein-A (VAP-A) interacts with the oxysterol-binding protein to modify export from the endoplasmic reticulum. |journal=J. Biol. Chem. |volume=277 |issue= 33 |pages= 29908–18 |year= 2002 |pmid= 12023275 |doi= 10.1074/jbc.M201191200
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Matsuda A, Suzuki Y, Honda G, "et al." |title=Large-scale identification and characterization of human genes that activate NF-kappaB and MAPK signaling pathways. |journal=Oncogene |volume=22 |issue= 21 |pages= 3307–18 |year= 2003 |pmid= 12761501 |doi= 10.1038/sj.onc.1206406
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Gao L, Aizaki H, He JW, Lai MM |title=Interactions between viral nonstructural proteins and host protein hVAP-33 mediate the formation of hepatitis C virus RNA replication complex on lipid raft. |journal=J. Virol. |volume=78 |issue= 7 |pages= 3480–8 |year= 2004 |pmid= 15016871 |doi=
*cite journal | author=Evans MJ, Rice CM, Goff SP |title=Phosphorylation of hepatitis C virus nonstructural protein 5A modulates its protein interactions and viral RNA replication. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 35 |pages= 13038–43 |year= 2004 |pmid= 15326295 |doi= 10.1073/pnas.0405152101
*cite journal | author=Suzuki Y, Yamashita R, Shirota M, "et al." |title=Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions. |journal=Genome Res. |volume=14 |issue= 9 |pages= 1711–8 |year= 2004 |pmid= 15342556 |doi= 10.1101/gr.2435604
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Rual JF, Venkatesan K, Hao T, "et al." |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209
*cite journal | author=Hamamoto I, Nishimura Y, Okamoto T, "et al." |title=Human VAP-B is involved in hepatitis C virus replication through interaction with NS5A and NS5B. |journal=J. Virol. |volume=79 |issue= 21 |pages= 13473–82 |year= 2005 |pmid= 16227268 |doi= 10.1128/JVI.79.21.13473-13482.2005
*cite journal | author=Kawano M, Kumagai K, Nishijima M, Hanada K |title=Efficient trafficking of ceramide from the endoplasmic reticulum to the Golgi apparatus requires a VAMP-associated protein-interacting FFAT motif of CERT. |journal=J. Biol. Chem. |volume=281 |issue= 40 |pages= 30279–88 |year= 2006 |pmid= 16895911 |doi= 10.1074/jbc.M605032200

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