BDP1

B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB, also known as BDP1, is a human gene.cite web | title = Entrez Gene: BDP1 B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=55814| accessdate = ]

PBB_Summary
section_title =
summary_text = The product of this gene is a subunit of the TFIIIB transcription initiation complex, which recruits RNA polymerase III to target promoters in order to initiate transcription. The encoded protein localizes to concentrated aggregates in the nucleus, and is required for transcription from all three types of polymerase III promoters. It is phosphorylated by casein kinase II during mitosis, resulting in its release from chromatin and suppression of polymerase III transcription.cite web | title = Entrez Gene: BDP1 B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=55814| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Chu WM, Wang Z, Roeder RG, Schmid CW |title=RNA polymerase III transcription repressed by Rb through its interactions with TFIIIB and TFIIIC2. |journal=J. Biol. Chem. |volume=272 |issue= 23 |pages= 14755–61 |year= 1997 |pmid= 9169441 |doi=
*cite journal | author=Wang Z, Roeder RG |title=Three human RNA polymerase III-specific subunits form a subcomplex with a selective function in specific transcription initiation. |journal=Genes Dev. |volume=11 |issue= 10 |pages= 1315–26 |year= 1997 |pmid= 9171375 |doi=
*cite journal | author=Nagase T, Ishikawa K, Kikuno R, "et al." |title=Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. |journal=DNA Res. |volume=6 |issue= 5 |pages= 337–45 |year= 2000 |pmid= 10574462 |doi=
*cite journal | author=Schramm L, Pendergrast PS, Sun Y, Hernandez N |title=Different human TFIIIB activities direct RNA polymerase III transcription from TATA-containing and TATA-less promoters. |journal=Genes Dev. |volume=14 |issue= 20 |pages= 2650–63 |year= 2000 |pmid= 11040218 |doi=
*cite journal | author=Kelter AR, Herchenbach J, Wirth B |title=The transcription factor-like nuclear regulator (TFNR) contains a novel 55-amino-acid motif repeated nine times and maps closely to SMN1. |journal=Genomics |volume=70 |issue= 3 |pages= 315–26 |year= 2001 |pmid= 11161782 |doi= 10.1006/geno.2000.6396
*cite journal | author=Nagase T, Kikuno R, Hattori A, "et al." |title=Prediction of the coding sequences of unidentified human genes. XIX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. |journal=DNA Res. |volume=7 |issue= 6 |pages= 347–55 |year= 2001 |pmid= 11214970 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Hu P, Wu S, Hernandez N |title=A minimal RNA polymerase III transcription system from human cells reveals positive and negative regulatory roles for CK2. |journal=Mol. Cell |volume=12 |issue= 3 |pages= 699–709 |year= 2003 |pmid= 14527415 |doi=
*cite journal | author=Fairley JA, Scott PH, White RJ |title=TFIIIB is phosphorylated, disrupted and selectively released from tRNA promoters during mitosis in vivo. |journal=EMBO J. |volume=22 |issue= 21 |pages= 5841–50 |year= 2003 |pmid= 14592981 |doi= 10.1093/emboj/cdg544
*cite journal | author=Weser S, Gruber C, Hafner HM, "et al." |title=Transcription factor (TF)-like nuclear regulator, the 250-kDa form of Homo sapiens TFIIIB", is an essential component of human TFIIIC1 activity. |journal=J. Biol. Chem. |volume=279 |issue= 26 |pages= 27022–9 |year= 2004 |pmid= 15096501 |doi= 10.1074/jbc.M312790200
*cite journal | author=Suzuki Y, Yamashita R, Shirota M, "et al." |title=Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions. |journal=Genome Res. |volume=14 |issue= 9 |pages= 1711–8 |year= 2004 |pmid= 15342556 |doi= 10.1101/gr.2435604
*cite journal | author=Hu P, Samudre K, Wu S, "et al." |title=CK2 phosphorylation of Bdp1 executes cell cycle-specific RNA polymerase III transcription repression. |journal=Mol. Cell |volume=16 |issue= 1 |pages= 81–92 |year= 2004 |pmid= 15469824 |doi= 10.1016/j.molcel.2004.09.008
*cite journal | author=Schoenen F, Wirth B |title=The zinc finger protein ZNF297B interacts with BDP1, a subunit of TFIIIB. |journal=Biol. Chem. |volume=387 |issue= 3 |pages= 277–84 |year= 2006 |pmid= 16542149 |doi= 10.1515/BC.2006.037
*cite journal | author=Johnson SS, Zhang C, Fromm J, "et al." |title=Mammalian Maf1 is a negative regulator of transcription by all three nuclear RNA polymerases. |journal=Mol. Cell |volume=26 |issue= 3 |pages= 367–79 |year= 2007 |pmid= 17499043 |doi= 10.1016/j.molcel.2007.03.021

PBB_Controls
update_page = yes
require_manual_inspection = no
update_protein_box = yes
update_summary = yes
update_citations = yes