MFN1

Mitofusin 1, also known as MFN1, is a human gene.cite web | title = Entrez Gene: MFN1 mitofusin 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=55669| accessdate = ]

PBB_Summary
section_title =
summary_text = The protein encoded by this gene is a mediator of mitochondrial fusion. This protein and mitofusin 2 are homologs of the Drosophila protein fuzzy onion (Fzo). They are mitochondrial membrane proteins that interact with each other to facilitate mitochondrial targeting.cite web | title = Entrez Gene: MFN1 mitofusin 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=55669| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Pawlikowska P, Orzechowski A |title= [Role of transmembrane GTPases in mitochondrial morphology and activity] |journal=Postepy Biochem. |volume=53 |issue= 1 |pages= 53–9 |year= 2007 |pmid= 17718388 |doi=
*cite journal | author=Adams MD, Kerlavage AR, Fields C, Venter JC |title=3,400 new expressed sequence tags identify diversity of transcripts in human brain. |journal=Nat. Genet. |volume=4 |issue= 3 |pages= 256–67 |year= 1993 |pmid= 8358434 |doi= 10.1038/ng0793-256
*cite journal | author=Andersson B, Wentland MA, Ricafrente JY, "et al." |title=A "double adaptor" method for improved shotgun library construction. |journal=Anal. Biochem. |volume=236 |issue= 1 |pages= 107–13 |year= 1996 |pmid= 8619474 |doi= 10.1006/abio.1996.0138
*cite journal | author=Yu W, Andersson B, Worley KC, "et al." |title=Large-scale concatenation cDNA sequencing. |journal=Genome Res. |volume=7 |issue= 4 |pages= 353–8 |year= 1997 |pmid= 9110174 |doi=
*cite journal | author=Hales KG, Fuller MT |title=Developmentally regulated mitochondrial fusion mediated by a conserved, novel, predicted GTPase. |journal=Cell |volume=90 |issue= 1 |pages= 121–9 |year= 1997 |pmid= 9230308 |doi=
*cite journal | author=Santel A, Fuller MT |title=Control of mitochondrial morphology by a human mitofusin. |journal=J. Cell. Sci. |volume=114 |issue= Pt 5 |pages= 867–74 |year= 2001 |pmid= 11181170 |doi=
*cite journal | author=Chung JG, Yeh KT, Wu SL, "et al." |title=Novel transmembrane GTPase of non-small cell lung cancer identified by mRNA differential display. |journal=Cancer Res. |volume=61 |issue= 24 |pages= 8873–9 |year= 2002 |pmid= 11751411 |doi=
*cite journal | author=Rojo M, Legros F, Chateau D, Lombès A |title=Membrane topology and mitochondrial targeting of mitofusins, ubiquitous mammalian homologs of the transmembrane GTPase Fzo. |journal=J. Cell. Sci. |volume=115 |issue= Pt 8 |pages= 1663–74 |year= 2003 |pmid= 11950885 |doi=
*cite journal | author=Legros F, Lombès A, Frachon P, Rojo M |title=Mitochondrial fusion in human cells is efficient, requires the inner membrane potential, and is mediated by mitofusins. |journal=Mol. Biol. Cell |volume=13 |issue= 12 |pages= 4343–54 |year= 2003 |pmid= 12475957 |doi= 10.1091/mbc.E02-06-0330
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Santel A, Frank S, Gaume B, "et al." |title=Mitofusin-1 protein is a generally expressed mediator of mitochondrial fusion in mammalian cells. |journal=J. Cell. Sci. |volume=116 |issue= Pt 13 |pages= 2763–74 |year= 2004 |pmid= 12759376 |doi= 10.1242/jcs.00479
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Cipolat S, Martins de Brito O, Dal Zilio B, Scorrano L |title=OPA1 requires mitofusin 1 to promote mitochondrial fusion. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 45 |pages= 15927–32 |year= 2004 |pmid= 15509649 |doi= 10.1073/pnas.0407043101
*cite journal | author=Cartoni R, Léger B, Hock MB, "et al." |title=Mitofusins 1/2 and ERRalpha expression are increased in human skeletal muscle after physical exercise. |journal=J. Physiol. (Lond.) |volume=567 |issue= Pt 1 |pages= 349–58 |year= 2005 |pmid= 15961417 |doi= 10.1113/jphysiol.2005.092031

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