TM4SF1

Transmembrane 4 L six family member 1, also known as TM4SF1, is a human gene.cite web | title = Entrez Gene: TM4SF1 transmembrane 4 L six family member 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=4071| accessdate = ]

PBB_Summary
section_title =
summary_text = The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface antigen and is highly expressed in different carcinomas.cite web | title = Entrez Gene: TM4SF1 transmembrane 4 L six family member 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=4071| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Berditchevski F |title=Complexes of tetraspanins with integrins: more than meets the eye. |journal=J. Cell. Sci. |volume=114 |issue= Pt 23 |pages= 4143–51 |year= 2002 |pmid= 11739647 |doi=
*cite journal | author=Marken JS, Schieven GL, Hellström I, "et al." |title=Cloning and expression of the tumor-associated antigen L6. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=89 |issue= 8 |pages= 3503–7 |year= 1992 |pmid= 1565644 |doi=
*cite journal | author=Marken JS, Bajorath J, Edwards CP, "et al." |title=Membrane topology of the L6 antigen and identification of the protein epitope recognized by the L6 monoclonal antibody. |journal=J. Biol. Chem. |volume=269 |issue= 10 |pages= 7397–401 |year= 1994 |pmid= 7510285 |doi=
*cite journal | author=Robertson NG, Khetarpal U, Gutiérrez-Espeleta GA, "et al." |title=Isolation of novel and known genes from a human fetal cochlear cDNA library using subtractive hybridization and differential screening. |journal=Genomics |volume=23 |issue= 1 |pages= 42–50 |year= 1995 |pmid= 7829101 |doi= 10.1006/geno.1994.1457
*cite journal | author=Virtaneva KI, Emi N, Marken JS, "et al." |title=Chromosomal localization of three human genes coding for A15, L6, and S5.7 (TAPA1): all members of the transmembrane 4 superfamily of proteins. |journal=Immunogenetics |volume=39 |issue= 5 |pages= 329–34 |year= 1994 |pmid= 8168850 |doi=
*cite journal | author=Borrell-Pagès M, Fernández-Larrea J, Borroto A, "et al." |title=The carboxy-terminal cysteine of the tetraspanin L6 antigen is required for its interaction with SITAC, a novel PDZ protein. |journal=Mol. Biol. Cell |volume=11 |issue= 12 |pages= 4217–25 |year= 2001 |pmid= 11102519 |doi=
*cite journal | author=Storim J, Friedl P, Schaefer BM, "et al." |title=Molecular and functional characterization of the four-transmembrane molecule l6 in epidermal keratinocytes. |journal=Exp. Cell Res. |volume=267 |issue= 2 |pages= 233–42 |year= 2001 |pmid= 11426942 |doi= 10.1006/excr.2001.5250
*cite journal | author=Kaneko R, Tsuji N, Kamagata C, "et al." |title=Amount of expression of the tumor-associated antigen L6 gene and transmembrane 4 superfamily member 5 gene in gastric cancers and gastric mucosa. |journal=Am. J. Gastroenterol. |volume=96 |issue= 12 |pages= 3457–8 |year= 2002 |pmid= 11774983 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Kao YR, Shih JY, Wen WC, "et al." |title=Tumor-associated antigen L6 and the invasion of human lung cancer cells. |journal=Clin. Cancer Res. |volume=9 |issue= 7 |pages= 2807–16 |year= 2004 |pmid= 12855661 |doi=
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Chang YW, Chen SC, Cheng EC, "et al." |title=CD13 (aminopeptidase N) can associate with tumor-associated antigen L6 and enhance the motility of human lung cancer cells. |journal=Int. J. Cancer |volume=116 |issue= 2 |pages= 243–52 |year= 2005 |pmid= 15812828 |doi= 10.1002/ijc.21089
*cite journal | author=Stelzl U, Worm U, Lalowski M, "et al." |title=A human protein-protein interaction network: a resource for annotating the proteome. |journal=Cell |volume=122 |issue= 6 |pages= 957–68 |year= 2005 |pmid= 16169070 |doi= 10.1016/j.cell.2005.08.029

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