- SCG3
Secretogranin III, also known as SCG3, is a human
gene .cite web | title = Entrez Gene: SCG3 secretogranin III| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=29106| accessdate = ]PBB_Summary
section_title =
summary_text = The protein encoded by this gene is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. Granins may serve as precursors for biologically active peptides. Some granins have been shown to function as helper proteins in sorting and proteolytic processing of prohormones; however, the function of this protein is unknown.cite web | title = Entrez Gene: SCG3 secretogranin III| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=29106| accessdate = ]References
Further reading
PBB_Further_reading
citations =
*cite journal | author=Huttner WB, Gerdes HH, Rosa P |title=The granin (chromogranin/secretogranin) family. |journal=Trends Biochem. Sci. |volume=16 |issue= 1 |pages= 27–30 |year= 1991 |pmid= 2053134 |doi=
*cite journal | author=Ozawa H, Takata K |title=The granin family--its role in sorting and secretory granule formation. |journal=Cell Struct. Funct. |volume=20 |issue= 6 |pages= 415–20 |year= 1996 |pmid= 8825061 |doi=
*cite journal | author=Dopazo A, Lovenberg TW, Danielson PE, "et al." |title=Primary structure of mouse secretogranin III and its absence from deficient mice. |journal=J. Mol. Neurosci. |volume=4 |issue= 4 |pages= 225–33 |year= 1994 |pmid= 7917832 |doi=
*cite journal | author=Holthuis JC, Jansen EJ, Martens GJ |title=Secretogranin III is a sulfated protein undergoing proteolytic processing in the regulated secretory pathway. |journal=J. Biol. Chem. |volume=271 |issue= 30 |pages= 17755–60 |year= 1996 |pmid= 8663421 |doi=
*cite journal | author=Rong YP, Liu F, Zeng LC, "et al." |title=Cloning and characterization of a novel human secretory protein: secretogranin III. |journal=Sheng Wu Hua Xue Yu Sheng Wu Wu Li Xue Bao |volume=34 |issue= 4 |pages= 411–7 |year= 2002 |pmid= 12098761 |doi=
*cite journal | author=Hosaka M, Watanabe T, Sakai Y, "et al." |title=Identification of a chromogranin A domain that mediates binding to secretogranin III and targeting to secretory granules in pituitary cells and pancreatic beta-cells. |journal=Mol. Biol. Cell |volume=13 |issue= 10 |pages= 3388–99 |year= 2003 |pmid= 12388744 |doi= 10.1091/mbc.02-03-0040
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Sakai Y, Hosaka M, Hira Y, "et al." |title=Immunocytochemical localization of secretogranin III in the anterior lobe of male rat pituitary glands. |journal=J. Histochem. Cytochem. |volume=51 |issue= 2 |pages= 227–38 |year= 2003 |pmid= 12533531 |doi=
*cite journal | author=Clark HF, Gurney AL, Abaya E, "et al." |title=The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. |journal=Genome Res. |volume=13 |issue= 10 |pages= 2265–70 |year= 2003 |pmid= 12975309 |doi= 10.1101/gr.1293003
*cite journal | author=Hosaka M, Suda M, Sakai Y, "et al." |title=Secretogranin III binds to cholesterol in the secretory granule membrane as an adapter for chromogranin A. |journal=J. Biol. Chem. |volume=279 |issue= 5 |pages= 3627–34 |year= 2004 |pmid= 14597614 |doi= 10.1074/jbc.M310104200
*cite journal | author=Sakai Y, Hosaka M, Yoshinaga A, "et al." |title=Immunocytochemical localization of secretogranin III in the endocrine pancreas of male rats. |journal=Arch. Histol. Cytol. |volume=67 |issue= 1 |pages= 57–64 |year= 2004 |pmid= 15125023 |doi=
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Otsuki T, Ota T, Nishikawa T, "et al." |title=Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries. |journal=DNA Res. |volume=12 |issue= 2 |pages= 117–26 |year= 2007 |pmid= 16303743 |doi= 10.1093/dnares/12.2.117
*cite journal | author=Tanabe A, Yanagiya T, Iida A, "et al." |title=Functional single-nucleotide polymorphisms in the secretogranin III (SCG3) gene that form secretory granules with appetite-related neuropeptides are associated with obesity. |journal=J. Clin. Endocrinol. Metab. |volume=92 |issue= 3 |pages= 1145–54 |year= 2007 |pmid= 17200173 |doi= 10.1210/jc.2006-1808PBB_Controls
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