- ARPC4
Actin related protein 2/3 complex, subunit 4, 20kDa, also known as ARPC4, is a human
gene .cite web | title = Entrez Gene: ARPC4 actin related protein 2/3 complex, subunit 4, 20kDa| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10093| accessdate = ]PBB_Summary
section_title =
summary_text = This gene encodes one of seven subunits of the human Arp2/3 protein complex. The Arp2/3 protein complex has been implicated in the control of actin polymerization in cells and has been conserved through evolution. The exact role of the protein encoded by this gene, the p20 subunit, has yet to be determined. Three transcript variants encoding two distinct isoforms have been found for this gene.cite web | title = Entrez Gene: ARPC4 actin related protein 2/3 complex, subunit 4, 20kDa| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10093| accessdate = ]References
Further reading
PBB_Further_reading
citations =
*cite journal | author=Welch MD, Iwamatsu A, Mitchison TJ |title=Actin polymerization is induced by Arp2/3 protein complex at the surface of Listeria monocytogenes. |journal=Nature |volume=385 |issue= 6613 |pages= 265–9 |year= 1997 |pmid= 9000076 |doi= 10.1038/385265a0
*cite journal | author=Welch MD, DePace AH, Verma S, "et al." |title=The human Arp2/3 complex is composed of evolutionarily conserved subunits and is localized to cellular regions of dynamic actin filament assembly. |journal=J. Cell Biol. |volume=138 |issue= 2 |pages= 375–84 |year= 1997 |pmid= 9230079 |doi=
*cite journal | author=Machesky LM, Reeves E, Wientjes F, "et al." |title=Mammalian actin-related protein 2/3 complex localizes to regions of lamellipodial protrusion and is composed of evolutionarily conserved proteins. |journal=Biochem. J. |volume=328 ( Pt 1) |issue= |pages= 105–12 |year= 1998 |pmid= 9359840 |doi=
*cite journal | author=Zhao X, Yang Z, Qian M, Zhu X |title=Interactions among subunits of human Arp2/3 complex: p20-Arc as the hub. |journal=Biochem. Biophys. Res. Commun. |volume=280 |issue= 2 |pages= 513–7 |year= 2001 |pmid= 11162547 |doi= 10.1006/bbrc.2000.4151
*cite journal | author=Robinson RC, Turbedsky K, Kaiser DA, "et al." |title=Crystal structure of Arp2/3 complex. |journal=Science |volume=294 |issue= 5547 |pages= 1679–84 |year= 2001 |pmid= 11721045 |doi= 10.1126/science.1066333
*cite journal | author=Gournier H, Goley ED, Niederstrasser H, "et al." |title=Reconstitution of human Arp2/3 complex reveals critical roles of individual subunits in complex structure and activity. |journal=Mol. Cell |volume=8 |issue= 5 |pages= 1041–52 |year= 2002 |pmid= 11741539 |doi=
*cite journal | author=Millard TH, Behrendt B, Launay S, "et al." |title=Identification and characterisation of a novel human isoform of Arp2/3 complex subunit p16-ARC/ARPC5. |journal=Cell Motil. Cytoskeleton |volume=54 |issue= 1 |pages= 81–90 |year= 2003 |pmid= 12451597 |doi= 10.1002/cm.10087
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Gevaert K, Goethals M, Martens L, "et al." |title=Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides. |journal=Nat. Biotechnol. |volume=21 |issue= 5 |pages= 566–9 |year= 2004 |pmid= 12665801 |doi= 10.1038/nbt810
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Andersen JS, Lam YW, Leung AK, "et al." |title=Nucleolar proteome dynamics. |journal=Nature |volume=433 |issue= 7021 |pages= 77–83 |year= 2005 |pmid= 15635413 |doi= 10.1038/nature03207
*cite journal | author=Stelzl U, Worm U, Lalowski M, "et al." |title=A human protein-protein interaction network: a resource for annotating the proteome. |journal=Cell |volume=122 |issue= 6 |pages= 957–68 |year= 2005 |pmid= 16169070 |doi= 10.1016/j.cell.2005.08.029
*cite journal | author=Rosentreter A, Hofmann A, Xavier CP, "et al." |title=Coronin 3 involvement in F-actin-dependent processes at the cell cortex. |journal=Exp. Cell Res. |volume=313 |issue= 5 |pages= 878–95 |year= 2007 |pmid= 17274980 |doi= 10.1016/j.yexcr.2006.12.015
*cite journal | author=Ewing RM, Chu P, Elisma F, "et al." |title=Large-scale mapping of human protein-protein interactions by mass spectrometry. |journal=Mol. Syst. Biol. |volume=3 |issue= |pages= 89 |year= 2007 |pmid= 17353931 |doi= 10.1038/msb4100134PBB_Controls
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