TEP1

Telomerase-associated protein 1, also known as TEP1, is a human gene.cite web | title = Entrez Gene: TEP1 telomerase-associated protein 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=7011| accessdate = ]

PBB_Summary
section_title =
summary_text = This gene product is a component of the ribonucleoprotein complex responsible for telomerase activity which catalyzes the addition of new telomeres on the chromosome ends. The telomerase-associated proteins are conserved from ciliates to humans.cite web | title = Entrez Gene: TEP1 telomerase-associated protein 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=7011| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Joly EC, Tremblay E, Tanguay RM, "et al." |title=TRiC-P5, a novel TCP1-related protein, is localized in the cytoplasm and in the nuclear matrix. |journal=J. Cell. Sci. |volume=107 ( Pt 10) |issue= |pages= 2851–9 |year= 1995 |pmid= 7876352 |doi=
*cite journal | author=Harrington L, McPhail T, Mar V, "et al." |title=A mammalian telomerase-associated protein. |journal=Science |volume=275 |issue= 5302 |pages= 973–7 |year= 1997 |pmid= 9020079 |doi=
*cite journal | author=Harrington L, Zhou W, McPhail T, "et al." |title=Human telomerase contains evolutionarily conserved catalytic and structural subunits. |journal=Genes Dev. |volume=11 |issue= 23 |pages= 3109–15 |year= 1998 |pmid= 9389643 |doi=
*cite journal | author=Saito T, Matsuda Y, Suzuki T, "et al." |title=Comparative gene mapping of the human and mouse TEP1 genes, which encode one protein component of telomerases. |journal=Genomics |volume=46 |issue= 1 |pages= 46–50 |year= 1998 |pmid= 9403057 |doi=
*cite journal | author=Li H, Zhao L, Yang Z, "et al." |title=Telomerase is controlled by protein kinase Calpha in human breast cancer cells. |journal=J. Biol. Chem. |volume=273 |issue= 50 |pages= 33436–42 |year= 1999 |pmid= 9837921 |doi=
*cite journal | author=Kickhoefer VA, Stephen AG, Harrington L, "et al." |title=Vaults and telomerase share a common subunit, TEP1. |journal=J. Biol. Chem. |volume=274 |issue= 46 |pages= 32712–7 |year= 2000 |pmid= 10551828 |doi=
*cite journal | author=Li H, Cao Y, Berndt MC, "et al." |title=Molecular interactions between telomerase and the tumor suppressor protein p53 in vitro. |journal=Oncogene |volume=18 |issue= 48 |pages= 6785–94 |year= 2000 |pmid= 10597287 |doi= 10.1038/sj.onc.1203061
*cite journal | author=Koyanagi Y, Kobayashi D, Yajima T, "et al." |title=Telomerase activity is down regulated via decreases in hTERT mRNA but not TEP1 mRNA or hTERC during the differentiation of leukemic cells. |journal=Anticancer Res. |volume=20 |issue= 2A |pages= 773–8 |year= 2000 |pmid= 10810353 |doi=
*cite journal | author=Beattie TL, Zhou W, Robinson MO, Harrington L |title=Polymerization defects within human telomerase are distinct from telomerase RNA and TEP1 binding. |journal=Mol. Biol. Cell |volume=11 |issue= 10 |pages= 3329–40 |year= 2000 |pmid= 11029039 |doi=
*cite journal | author=Zhang RG, Zhang RP, Wang XW, Xie H |title=Effects of cisplatin on telomerase activity and telomere length in BEL-7404 human hepatoma cells. |journal=Cell Res. |volume=12 |issue= 1 |pages= 55–62 |year= 2004 |pmid= 11942411 |doi= 10.1038/sj.cr.7290110
*cite journal | author=Chang JT, Chen YL, Yang HT, "et al." |title=Differential regulation of telomerase activity by six telomerase subunits. |journal=Eur. J. Biochem. |volume=269 |issue= 14 |pages= 3442–50 |year= 2002 |pmid= 12135483 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Zhou JH, Zhang HM, Chen Q, "et al." |title=Relationship between telomerase activity and its subunit expression and inhibitory effect of antisense hTR on pancreatic carcinoma. |journal=World J. Gastroenterol. |volume=9 |issue= 8 |pages= 1808–14 |year= 2003 |pmid= 12918126 |doi=
*cite journal | author=Li C, Wu MY, Liang YR, Wu XY |title=Correlation between expression of human telomerase subunits and telomerase activity in esophageal squamous cell carcinoma. |journal=World J. Gastroenterol. |volume=9 |issue= 11 |pages= 2395–9 |year= 2003 |pmid= 14606063 |doi=
*cite journal | author=Lim J, Hao T, Shaw C, "et al." |title=A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration. |journal=Cell |volume=125 |issue= 4 |pages= 801–14 |year= 2006 |pmid= 16713569 |doi= 10.1016/j.cell.2006.03.032

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