ABCB9

ATP-binding cassette, sub-family B (MDR/TAP), member 9, also known as ABCB9, is a human gene.cite web | title = Entrez Gene: ABCB9 ATP-binding cassette, sub-family B (MDR/TAP), member 9| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=23457| accessdate = ]

PBB_Summary
section_title =
summary_text = The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. The function of this half-transporter has not yet been determined; however, this protein may play a role in lysosomes. Alternative splicing of this gene results in distinct isoforms which are likely to have different substrate specifications.cite web | title = Entrez Gene: ABCB9 ATP-binding cassette, sub-family B (MDR/TAP), member 9| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=23457| accessdate = ]

ee also

* ATP-binding cassette transporter

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Bonaldo MF, Lennon G, Soares MB |title=Normalization and subtraction: two approaches to facilitate gene discovery. |journal=Genome Res. |volume=6 |issue= 9 |pages= 791–806 |year= 1997 |pmid= 8889548 |doi=
*cite journal | author=Allikmets R, Gerrard B, Hutchinson A, Dean M |title=Characterization of the human ABC superfamily: isolation and mapping of 21 new genes using the expressed sequence tags database. |journal=Hum. Mol. Genet. |volume=5 |issue= 10 |pages= 1649–55 |year= 1997 |pmid= 8894702 |doi=
*cite journal | author=Zhang F, Zhang W, Liu L, "et al." |title=Characterization of ABCB9, an ATP binding cassette protein associated with lysosomes. |journal=J. Biol. Chem. |volume=275 |issue= 30 |pages= 23287–94 |year= 2000 |pmid= 10748049 |doi= 10.1074/jbc.M001819200
*cite journal | author=Nagase T, Kikuno R, Ishikawa K, "et al." |title=Prediction of the coding sequences of unidentified human genes. XVII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. |journal=DNA Res. |volume=7 |issue= 2 |pages= 143–50 |year= 2000 |pmid= 10819331 |doi=
*cite journal | author=Kobayashi A, Kasano M, Maeda T, "et al." |title=A half-type ABC transporter TAPL is highly conserved between rodent and man, and the human gene is not responsive to interferon-gamma in contrast to TAP1 and TAP2. |journal=J. Biochem. |volume=128 |issue= 4 |pages= 711–8 |year= 2000 |pmid= 11011155 |doi=
*cite journal | author=Saito S, Iida A, Sekine A, "et al." |title=Three hundred twenty-six genetic variations in genes encoding nine members of ATP-binding cassette, subfamily B (ABCB/MDR/TAP), in the Japanese population. |journal=J. Hum. Genet. |volume=47 |issue= 1 |pages= 38–50 |year= 2002 |pmid= 11829140 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Kobayashi A, Hori S, Suita N, Maeda M |title=Gene organization of human transporter associated with antigen processing-like (TAPL, ABCB9): analysis of alternative splicing variants and promoter activity. |journal=Biochem. Biophys. Res. Commun. |volume=309 |issue= 4 |pages= 815–22 |year= 2003 |pmid= 13679046 |doi=
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Beausoleil SA, Jedrychowski M, Schwartz D, "et al." |title=Large-scale characterization of HeLa cell nuclear phosphoproteins. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 33 |pages= 12130–5 |year= 2004 |pmid= 15302935 |doi= 10.1073/pnas.0404720101
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Homma K, Kikuno RF, Nagase T, "et al." |title=Alternative splice variants encoding unstable protein domains exist in the human brain. |journal=J. Mol. Biol. |volume=343 |issue= 5 |pages= 1207–20 |year= 2004 |pmid= 15491607 |doi= 10.1016/j.jmb.2004.09.028
*cite journal | author=Wolters JC, Abele R, Tampé R |title=Selective and ATP-dependent translocation of peptides by the homodimeric ATP binding cassette transporter TAP-like (ABCB9). |journal=J. Biol. Chem. |volume=280 |issue= 25 |pages= 23631–6 |year= 2005 |pmid= 15863492 |doi= 10.1074/jbc.M503231200
*cite journal | author=Kimura K, Wakamatsu A, Suzuki Y, "et al." |title=Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. |journal=Genome Res. |volume=16 |issue= 1 |pages= 55–65 |year= 2006 |pmid= 16344560 |doi= 10.1101/gr.4039406
*cite journal | author=Ohashi-Kobayashi A, Ohashi K, Du WB, "et al." |title=Examination of drug resistance activity of human TAP-like (ABCB9) expressed in yeast. |journal=Biochem. Biophys. Res. Commun. |volume=343 |issue= 2 |pages= 597–601 |year= 2006 |pmid= 16554024 |doi= 10.1016/j.bbrc.2006.03.002

External links

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