- TAF8
Taube nuss homolog (mouse), also known as TBN, is a human
gene .cite web | title = Entrez Gene: TBN taube nuss homolog (mouse)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=129685| accessdate = ]PBB_Summary
section_title =
summary_text = This gene encodes one of several TATA-binding protein (TBP)-associated factors (TAFs), which are integral subunits of the general transcription factor complex TFIID. TFIID recognizes the core promoter of many genes and nucleates the assembly of a transcription preinitiation complex containing RNA polymerase II and other initiation factors. The protein encoded by this gene contains an H4-like histone fold domain, and interacts with several subunits of TFIID including TBP and the histone-fold protein TAF10. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.cite web | title = Entrez Gene: TBN taube nuss homolog (mouse)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=129685| accessdate = ]References
Further reading
PBB_Further_reading
citations =
*cite journal | author=Zhou Q, Sharp PA |title=Novel mechanism and factor for regulation by HIV-1 Tat. |journal=EMBO J. |volume=14 |issue= 2 |pages= 321–8 |year= 1995 |pmid= 7835343 |doi=
*cite journal | author=Parada CA, Yoon JB, Roeder RG |title=A novel LBP-1-mediated restriction of HIV-1 transcription at the level of elongation in vitro. |journal=J. Biol. Chem. |volume=270 |issue= 5 |pages= 2274–83 |year= 1995 |pmid= 7836461 |doi=
*cite journal | author=Ou SH, Garcia-Martínez LF, Paulssen EJ, Gaynor RB |title=Role of flanking E box motifs in human immunodeficiency virus type 1 TATA element function. |journal=J. Virol. |volume=68 |issue= 11 |pages= 7188–99 |year= 1994 |pmid= 7933101 |doi=
*cite journal | author=Kashanchi F, Piras G, Radonovich MF, "et al." |title=Direct interaction of human TFIID with the HIV-1 transactivator tat. |journal=Nature |volume=367 |issue= 6460 |pages= 295–9 |year= 1994 |pmid= 8121496 |doi= 10.1038/367295a0
*cite journal | author=Wang Z, Morris GF, Rice AP, "et al." |title=Wild-type and transactivation-defective mutants of human immunodeficiency virus type 1 Tat protein bind human TATA-binding protein in vitro. |journal=J. Acquir. Immune Defic. Syndr. Hum. Retrovirol. |volume=12 |issue= 2 |pages= 128–38 |year= 1996 |pmid= 8680883 |doi=
*cite journal | author=Pendergrast PS, Morrison D, Tansey WP, Hernandez N |title=Mutations in the carboxy-terminal domain of TBP affect the synthesis of human immunodeficiency virus type 1 full-length and short transcripts similarly. |journal=J. Virol. |volume=70 |issue= 8 |pages= 5025–34 |year= 1996 |pmid= 8764009 |doi=
*cite journal | author=Kashanchi F, Khleif SN, Duvall JF, "et al." |title=Interaction of human immunodeficiency virus type 1 Tat with a unique site of TFIID inhibits negative cofactor Dr1 and stabilizes the TFIID-TFIIA complex. |journal=J. Virol. |volume=70 |issue= 8 |pages= 5503–10 |year= 1996 |pmid= 8764062 |doi=
*cite journal | author=Zhou Q, Sharp PA |title=Tat-SF1: cofactor for stimulation of transcriptional elongation by HIV-1 Tat. |journal=Science |volume=274 |issue= 5287 |pages= 605–10 |year= 1996 |pmid= 8849451 |doi=
*cite journal | author=García-Martínez LF, Ivanov D, Gaynor RB |title=Association of Tat with purified HIV-1 and HIV-2 transcription preinitiation complexes. |journal=J. Biol. Chem. |volume=272 |issue= 11 |pages= 6951–8 |year= 1997 |pmid= 9054383 |doi=
*cite journal | author=Purrello M, Di Pietro C, Viola A, "et al." |title=Genomics and transcription analysis of human TFIID. |journal=Oncogene |volume=16 |issue= 12 |pages= 1633–8 |year= 1998 |pmid= 9569032 |doi= 10.1038/sj.onc.1201673
*cite journal | author=Guermah M, Tao Y, Roeder RG |title=Positive and negative TAF(II) functions that suggest a dynamic TFIID structure and elicit synergy with traps in activator-induced transcription. |journal=Mol. Cell. Biol. |volume=21 |issue= 20 |pages= 6882–94 |year= 2001 |pmid= 11564872 |doi= 10.1128/MCB.21.20.6882-6894.2001
*cite journal | author=Tora L |title=A unified nomenclature for TATA box binding protein (TBP)-associated factors (TAFs) involved in RNA polymerase II transcription. |journal=Genes Dev. |volume=16 |issue= 6 |pages= 673–5 |year= 2002 |pmid= 11963920 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Guermah M, Ge K, Chiang CM, Roeder RG |title=The TBN protein, which is essential for early embryonic mouse development, is an inducible TAFII implicated in adipogenesis. |journal=Mol. Cell |volume=12 |issue= 4 |pages= 991–1001 |year= 2003 |pmid= 14580349 |doi=
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Soutoglou E, Demény MA, Scheer E, "et al." |title=The nuclear import of TAF10 is regulated by one of its three histone fold domain-containing interaction partners. |journal=Mol. Cell. Biol. |volume=25 |issue= 10 |pages= 4092–104 |year= 2005 |pmid= 15870280 |doi= 10.1128/MCB.25.10.4092-4104.2005PBB_Controls
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