FCRL3

Fc receptor-like 3, also known as FCRL3, is a human gene.cite web | title = Entrez Gene: FCRL3 Fc receptor-like 3| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=115352| accessdate = ]

PBB_Summary
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summary_text = This gene encodes a member of the immunoglobulin receptor superfamily and is one of several Fc receptor-like glycoproteins clustered on the long arm of chromosome 1. The encoded protein contains immunoreceptor-tyrosine activation motifs and immunoreceptor-tyrosine inhibitory motifs in its cytoplasmic domain and may play a role in regulation of the immune system. Mutations in this gene have been associated with rheumatoid arthritis, autoimmune thyroid disease, and systemic lupus erythematosus.cite web | title = Entrez Gene: FCRL3 Fc receptor-like 3| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=115352| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Davis RS, Dennis G, Kubagawa H, Cooper MD |title=Fc receptor homologs (FcRH1-5) extend the Fc receptor family. |journal=Curr. Top. Microbiol. Immunol. |volume=266 |issue= |pages= 85–112 |year= 2002 |pmid= 12014205 |doi=
*cite journal | author=Davis RS, Wang YH, Kubagawa H, Cooper MD |title=Identification of a family of Fc receptor homologs with preferential B cell expression. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=98 |issue= 17 |pages= 9772–7 |year= 2001 |pmid= 11493702 |doi= 10.1073/pnas.171308498
*cite journal | author=Miller I, Hatzivassiliou G, Cattoretti G, "et al." |title=IRTAs: a new family of immunoglobulinlike receptors differentially expressed in B cells. |journal=Blood |volume=99 |issue= 8 |pages= 2662–9 |year= 2002 |pmid= 11929751 |doi=
*cite journal | author=Xu MJ, Zhao R, Cao H, Zhao ZJ |title=SPAP2, an Ig family receptor containing both ITIMs and ITAMs. |journal=Biochem. Biophys. Res. Commun. |volume=293 |issue= 3 |pages= 1037–46 |year= 2002 |pmid= 12051764 |doi= 10.1016/S0006-291X(02)00332-7
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Kochi Y, Yamada R, Suzuki A, "et al." |title=A functional variant in FCRL3, encoding Fc receptor-like 3, is associated with rheumatoid arthritis and several autoimmunities. |journal=Nat. Genet. |volume=37 |issue= 5 |pages= 478–85 |year= 2005 |pmid= 15838509 |doi= 10.1038/ng1540
*cite journal | author=Simmonds MJ, Heward JM, Carr-Smith J, "et al." |title=Contribution of single nucleotide polymorphisms within FCRL3 and MAP3K7IP2 to the pathogenesis of Graves' disease. |journal=J. Clin. Endocrinol. Metab. |volume=91 |issue= 3 |pages= 1056–61 |year= 2006 |pmid= 16384851 |doi= 10.1210/jc.2005-1634
*cite journal | author=Eyre S, Bowes J, Potter C, "et al." |title=Association of the FCRL3 gene with rheumatoid arthritis: a further example of population specificity? |journal=Arthritis Res. Ther. |volume=8 |issue= 4 |pages= R117 |year= 2007 |pmid= 16859508 |doi= 10.1186/ar2006
*cite journal | author=Umemura T, Ota M, Yoshizawa K, "et al." |title=Lack of association between FCRL3 and FcgammaRII polymorphisms in Japanese type 1 autoimmune hepatitis. |journal=Clin. Immunol. |volume=122 |issue= 3 |pages= 338–42 |year= 2007 |pmid= 17020818 |doi= 10.1016/j.clim.2006.08.012
*cite journal | author=Schäfer N, Blaumeiser B, Becker T, "et al." |title=Investigation of the functional variant c.-169T > C of the Fc receptor-like 3 (FCRL3) gene in alopecia areata. |journal=Int. J. Immunogenet. |volume=33 |issue= 6 |pages= 393–5 |year= 2007 |pmid= 17117947 |doi= 10.1111/j.1744-313X.2006.00633.x
*cite journal | author=Newman WG, Zhang Q, Liu X, "et al." |title=Rheumatoid arthritis association with the FCRL3 -169C polymorphism is restricted to PTPN22 1858T-homozygous individuals in a Canadian population. |journal=Arthritis Rheum. |volume=54 |issue= 12 |pages= 3820–7 |year= 2007 |pmid= 17133579 |doi= 10.1002/art.22270
*cite journal | author=Choi CB, Kang CP, Seong SS, "et al." |title=The -169C/T polymorphism in FCRL3 is not associated with susceptibility to rheumatoid arthritis or systemic lupus erythematosus in a case-control study of Koreans. |journal=Arthritis Rheum. |volume=54 |issue= 12 |pages= 3838–41 |year= 2007 |pmid= 17133581 |doi= 10.1002/art.22248
*cite journal | author=Owen CJ, Kelly H, Eden JA, "et al." |title=Analysis of the Fc receptor-like-3 (FCRL3) locus in Caucasians with autoimmune disorders suggests a complex pattern of disease association. |journal=J. Clin. Endocrinol. Metab. |volume=92 |issue= 3 |pages= 1106–11 |year= 2007 |pmid= 17200162 |doi= 10.1210/jc.2006-2183
*cite journal | author=Taylor AI, Gould HJ, Sutton BJ, Calvert RA |title=The first avian Ig-like Fc receptor family member combines features of mammalian FcR and FCRL. |journal=Immunogenetics |volume=59 |issue= 4 |pages= 323–8 |year= 2007 |pmid= 17273841 |doi= 10.1007/s00251-007-0195-9
*cite journal | author=Martínez A, Núñez C, Martín MC, "et al." |title=Epistatic interaction between FCRL3 and MHC in Spanish patients with IBD. |journal=Tissue Antigens |volume=69 |issue= 4 |pages= 313–7 |year= 2007 |pmid= 17389014 |doi= 10.1111/j.1399-0039.2007.00816.x
*cite journal | author=Martínez A, Mas A, de Las Heras V, "et al." |title=FcRL3 and multiple sclerosis pathogenesis: role in autoimmunity? |journal=J. Neuroimmunol. |volume=189 |issue= 1-2 |pages= 132–6 |year= 2007 |pmid= 17617473 |doi= 10.1016/j.jneuroim.2007.06.018

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