RAB2A

RAB2A, member RAS oncogene family, also known as RAB2A, is a human gene.cite web | title = Entrez Gene: RAB2A RAB2A, member RAS oncogene family| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=5862| accessdate = ]

PBB_Summary
section_title =
summary_text = Members of the Rab protein family are nontransforming monomeric GTP-binding proteins of the Ras superfamily that contain 4 highly conserved regions involved in GTP binding and hydrolysis. Rabs are prenylated, membrane-bound proteins involved in vesicular fusion and trafficking. The mammalian RAB proteins show striking similarities to the S. cerevisiae YPT1 and SEC4 proteins, Ras-related GTP-binding proteins involved in the regulation of secretion. [supplied by OMIM] cite web | title = Entrez Gene: RAB2A RAB2A, member RAS oncogene family| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=5862| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Khosravi-Far R, Lutz RJ, Cox AD, "et al." |title=Isoprenoid modification of rab proteins terminating in CC or CXC motifs. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=88 |issue= 14 |pages= 6264–8 |year= 1991 |pmid= 1648736 |doi=
*cite journal | author=Zahraoui A, Touchot N, Chardin P, Tavitian A |title=The human Rab genes encode a family of GTP-binding proteins related to yeast YPT1 and SEC4 products involved in secretion. |journal=J. Biol. Chem. |volume=264 |issue= 21 |pages= 12394–401 |year= 1989 |pmid= 2501306 |doi=
*cite journal | author=Tachibana K, Umezawa A, Kato S, Takano T |title=Nucleotide sequence of a new YPT1-related human cDNA which belongs to the ras gene superfamily. |journal=Nucleic Acids Res. |volume=16 |issue= 21 |pages= 10368 |year= 1989 |pmid= 3057444 |doi=
*cite journal | author=Andersson B, Wentland MA, Ricafrente JY, "et al." |title=A "double adaptor" method for improved shotgun library construction. |journal=Anal. Biochem. |volume=236 |issue= 1 |pages= 107–13 |year= 1996 |pmid= 8619474 |doi= 10.1006/abio.1996.0138
*cite journal | author=Tisdale EJ, Balch WE |title=Rab2 is essential for the maturation of pre-Golgi intermediates. |journal=J. Biol. Chem. |volume=271 |issue= 46 |pages= 29372–9 |year= 1997 |pmid= 8910601 |doi=
*cite journal | author=Yu W, Andersson B, Worley KC, "et al." |title=Large-scale concatenation cDNA sequencing. |journal=Genome Res. |volume=7 |issue= 4 |pages= 353–8 |year= 1997 |pmid= 9110174 |doi=
*cite journal | author=de Leeuw HP, Koster PM, Calafat J, "et al." |title=Small GTP-binding proteins in human endothelial cells. |journal=Br. J. Haematol. |volume=103 |issue= 1 |pages= 15–9 |year= 1998 |pmid= 9792283 |doi=
*cite journal | author=Shisheva A, Chinni SR, DeMarco C |title=General role of GDP dissociation inhibitor 2 in membrane release of Rab proteins: modulations of its functional interactions by in vitro and in vivo structural modifications. |journal=Biochemistry |volume=38 |issue= 36 |pages= 11711–21 |year= 1999 |pmid= 10512627 |doi=
*cite journal | author=Caillol N, Pasqualini E, Lloubes R, Lombardo D |title=Impairment of bile salt-dependent lipase secretion in human pancreatic tumoral SOJ-6 cells. |journal=J. Cell. Biochem. |volume=79 |issue= 4 |pages= 628–47 |year= 2000 |pmid= 10996854 |doi=
*cite journal | author=Short B, Preisinger C, Körner R, "et al." |title=A GRASP55-rab2 effector complex linking Golgi structure to membrane traffic. |journal=J. Cell Biol. |volume=155 |issue= 6 |pages= 877–83 |year= 2002 |pmid= 11739401 |doi= 10.1083/jcb.200108079
*cite journal | author=Ni X, Ma Y, Cheng H, "et al." |title=Molecular cloning and characterization of a novel human Rab ( Rab2B) gene. |journal=J. Hum. Genet. |volume=47 |issue= 10 |pages= 548–51 |year= 2002 |pmid= 12376746 |doi= 10.1007/s100380200083
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Tisdale EJ |title=Rab2 interacts directly with atypical protein kinase C (aPKC) iota/lambda and inhibits aPKCiota/lambda-dependent glyceraldehyde-3-phosphate dehydrogenase phosphorylation. |journal=J. Biol. Chem. |volume=278 |issue= 52 |pages= 52524–30 |year= 2004 |pmid= 14570876 |doi= 10.1074/jbc.M309343200
*cite journal | author=Tisdale EJ, Kelly C, Artalejo CR |title=Glyceraldehyde-3-phosphate dehydrogenase interacts with Rab2 and plays an essential role in endoplasmic reticulum to Golgi transport exclusive of its glycolytic activity. |journal=J. Biol. Chem. |volume=279 |issue= 52 |pages= 54046–52 |year= 2005 |pmid= 15485821 |doi= 10.1074/jbc.M409472200
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Rual JF, Venkatesan K, Hao T, "et al." |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209
*cite journal | author=Chi A, Valencia JC, Hu ZZ, "et al." |title=Proteomic and bioinformatic characterization of the biogenesis and function of melanosomes. |journal=J. Proteome Res. |volume=5 |issue= 11 |pages= 3135–44 |year= 2007 |pmid= 17081065 |doi= 10.1021/pr060363j
*cite journal | author=Dong C, Wu G |title=Regulation of anterograde transport of adrenergic and angiotensin II receptors by Rab2 and Rab6 GTPases. |journal=Cell. Signal. |volume=19 |issue= 11 |pages= 2388–99 |year= 2007 |pmid= 17716866 |doi= 10.1016/j.cellsig.2007.07.017

PBB_Controls
update_page = yes
require_manual_inspection = no
update_protein_box = yes
update_summary = yes
update_citations = yes