PNPLA2

PNPLA2

Patatin-like phospholipase domain containing 2, also known as PNPLA2, is a human gene.cite web | title = Entrez Gene: PNPLA2 patatin-like phospholipase domain containing 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=57104| accessdate = ]

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References

Further reading

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*cite journal | author=Andersson B, Wentland MA, Ricafrente JY, "et al." |title=A "double adaptor" method for improved shotgun library construction. |journal=Anal. Biochem. |volume=236 |issue= 1 |pages= 107–13 |year= 1996 |pmid= 8619474 |doi= 10.1006/abio.1996.0138
*cite journal | author=Yu W, Andersson B, Worley KC, "et al." |title=Large-scale concatenation cDNA sequencing. |journal=Genome Res. |volume=7 |issue= 4 |pages= 353–8 |year= 1997 |pmid= 9110174 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Colland F, Jacq X, Trouplin V, "et al." |title=Functional proteomics mapping of a human signaling pathway. |journal=Genome Res. |volume=14 |issue= 7 |pages= 1324–32 |year= 2004 |pmid= 15231748 |doi= 10.1101/gr.2334104
*cite journal | author=Villena JA, Roy S, Sarkadi-Nagy E, "et al." |title=Desnutrin, an adipocyte gene encoding a novel patatin domain-containing protein, is induced by fasting and glucocorticoids: ectopic expression of desnutrin increases triglyceride hydrolysis. |journal=J. Biol. Chem. |volume=279 |issue= 45 |pages= 47066–75 |year= 2004 |pmid= 15337759 |doi= 10.1074/jbc.M403855200
*cite journal | author=Jenkins CM, Mancuso DJ, Yan W, "et al." |title=Identification, cloning, expression, and purification of three novel human calcium-independent phospholipase A2 family members possessing triacylglycerol lipase and acylglycerol transacylase activities. |journal=J. Biol. Chem. |volume=279 |issue= 47 |pages= 48968–75 |year= 2005 |pmid= 15364929 |doi= 10.1074/jbc.M407841200
*cite journal | author=Zimmermann R, Strauss JG, Haemmerle G, "et al." |title=Fat mobilization in adipose tissue is promoted by adipose triglyceride lipase. |journal=Science |volume=306 |issue= 5700 |pages= 1383–6 |year= 2004 |pmid= 15550674 |doi= 10.1126/science.1100747
*cite journal | author=Rual JF, Venkatesan K, Hao T, "et al." |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209
*cite journal | author=Smirnova E, Goldberg EB, Makarova KS, "et al." |title=ATGL has a key role in lipid droplet/adiposome degradation in mammalian cells. |journal=EMBO Rep. |volume=7 |issue= 1 |pages= 106–13 |year= 2006 |pmid= 16239926 |doi= 10.1038/sj.embor.7400559
*cite journal | author=Schoenborn V, Heid IM, Vollmert C, "et al." |title=The ATGL gene is associated with free fatty acids, triglycerides, and type 2 diabetes. |journal=Diabetes |volume=55 |issue= 5 |pages= 1270–5 |year= 2006 |pmid= 16644682 |doi=
*cite journal | author=Lass A, Zimmermann R, Haemmerle G, "et al." |title=Adipose triglyceride lipase-mediated lipolysis of cellular fat stores is activated by CGI-58 and defective in Chanarin-Dorfman Syndrome. |journal=Cell Metab. |volume=3 |issue= 5 |pages= 309–19 |year= 2007 |pmid= 16679289 |doi= 10.1016/j.cmet.2006.03.005
*cite journal | author=Mairal A, Langin D, Arner P, Hoffstedt J |title=Human adipose triglyceride lipase (PNPLA2) is not regulated by obesity and exhibits low in vitro triglyceride hydrolase activity. |journal=Diabetologia |volume=49 |issue= 7 |pages= 1629–36 |year= 2007 |pmid= 16752181 |doi= 10.1007/s00125-006-0272-x
*cite journal | author=Wilson PA, Gardner SD, Lambie NM, "et al." |title=Characterization of the human patatin-like phospholipase family. |journal=J. Lipid Res. |volume=47 |issue= 9 |pages= 1940–9 |year= 2006 |pmid= 16799181 |doi= 10.1194/jlr.M600185-JLR200
*cite journal | author=Notari L, Baladron V, Aroca-Aguilar JD, "et al." |title=Identification of a lipase-linked cell membrane receptor for pigment epithelium-derived factor. |journal=J. Biol. Chem. |volume=281 |issue= 49 |pages= 38022–37 |year= 2007 |pmid= 17032652 |doi= 10.1074/jbc.M600353200
*cite journal | author=Fischer J, Lefèvre C, Morava E, "et al." |title=The gene encoding adipose triglyceride lipase (PNPLA2) is mutated in neutral lipid storage disease with myopathy. |journal=Nat. Genet. |volume=39 |issue= 1 |pages= 28–30 |year= 2007 |pmid= 17187067 |doi= 10.1038/ng1951
*cite journal | author=Rydén M, Jocken J, van Harmelen V, "et al." |title=Comparative studies of the role of hormone-sensitive lipase and adipose triglyceride lipase in human fat cell lipolysis. |journal=Am. J. Physiol. Endocrinol. Metab. |volume=292 |issue= 6 |pages= E1847–55 |year= 2007 |pmid= 17327373 |doi= 10.1152/ajpendo.00040.2007
*cite journal | author=Jocken JW, Langin D, Smit E, "et al." |title=Adipose triglyceride lipase and hormone-sensitive lipase protein expression is decreased in the obese insulin-resistant state. |journal=J. Clin. Endocrinol. Metab. |volume=92 |issue= 6 |pages= 2292–9 |year= 2007 |pmid= 17356053 |doi= 10.1210/jc.2006-1318
*cite journal | author=Steinberg GR, Kemp BE, Watt MJ |title=Adipocyte triglyceride lipase expression in human obesity. |journal=Am. J. Physiol. Endocrinol. Metab. |volume=293 |issue= 4 |pages= E958–64 |year= 2007 |pmid= 17609260 |doi= 10.1152/ajpendo.00235.2007
*cite journal | author=Fischer J, Negre-Salvayre A, Salvayre R |title= [Neutral lipid storage diseases and ATGL (adipose triglyceride lipase) and CGI-58/ABHD5 (alpha-beta hydrolase domain-containing 5) deficiency: myopathy, ichthyosis, but no obesity] |journal=Med Sci (Paris) |volume=23 |issue= 6-7 |pages= 575–8 |year= 2007 |pmid= 17631826 |doi=

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  • Patatin-like phospholipase — Pfam box Symbol = Patatin Name = width =200 caption =Patatin Pfam= PF01734 InterPro= IPR002641 SMART= PROSITE = PDOC00951 SCOP = 1oxw TCDB = OPM family= 134 OPM protein= 1oxw PDB=PDB3|1oxwC:32 228Family of patatin like phospholipases consists of… …   Wikipedia

  • Mark Lathrop — Born 1950 Citizenship Canada Fields …   Wikipedia

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