TBCE

TBCE

Tubulin folding cofactor E, also known as TBCE, is a human gene.cite web | title = Entrez Gene: TBCE tubulin folding cofactor E| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6905| accessdate = ]

PBB_Summary
section_title =
summary_text = Cofactor E is one of four proteins (cofactors A, D, E, and C) involved in the pathway leading to correctly folded beta-tubulin from folding intermediates. Cofactors A and D are believed to play a role in capturing and stabilizing beta-tubulin intermediates in a quasi-native confirmation. Cofactor E binds to the cofactor D/beta-tubulin complex; interaction with cofactor C then causes the release of beta-tubulin polypeptides that are committed to the native state. Two transcript variants encoding the same protein have been found for this gene.cite web | title = Entrez Gene: TBCE tubulin folding cofactor E| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6905| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Lewis SA, Tian G, Vainberg IE, Cowan NJ |title=Chaperonin-mediated folding of actin and tubulin. |journal=J. Cell Biol. |volume=132 |issue= 1-2 |pages= 1–4 |year= 1996 |pmid= 8567715 |doi=
*cite journal | author=Parvari R, Diaz GA, Hershkovitz E |title=Parathyroid development and the role of tubulin chaperone E. |journal=Horm. Res. |volume=67 |issue= 1 |pages= 12–21 |year= 2007 |pmid= 17008776 |doi= 10.1159/000095944
*cite journal | author=Tian G, Huang Y, Rommelaere H, "et al." |title=Pathway leading to correctly folded beta-tubulin. |journal=Cell |volume=86 |issue= 2 |pages= 287–96 |year= 1996 |pmid= 8706133 |doi=
*cite journal | author=Tian G, Lewis SA, Feierbach B, "et al." |title=Tubulin subunits exist in an activated conformational state generated and maintained by protein cofactors. |journal=J. Cell Biol. |volume=138 |issue= 4 |pages= 821–32 |year= 1997 |pmid= 9265649 |doi=
*cite journal | author=Parvari R, Hershkovitz E, Kanis A, "et al." |title=Homozygosity and linkage-disequilibrium mapping of the syndrome of congenital hypoparathyroidism, growth and mental retardation, and dysmorphism to a 1-cM interval on chromosome 1q42-43. |journal=Am. J. Hum. Genet. |volume=63 |issue= 1 |pages= 163–9 |year= 1998 |pmid= 9634513 |doi=
*cite journal | author=Diaz GA, Khan KT, Gelb BD |title=The autosomal recessive Kenny-Caffey syndrome locus maps to chromosome 1q42-q43. |journal=Genomics |volume=54 |issue= 1 |pages= 13–8 |year= 1999 |pmid= 9806825 |doi= 10.1006/geno.1998.5530
*cite journal | author=Roobol A, Sahyoun ZP, Carden MJ |title=Selected subunits of the cytosolic chaperonin associate with microtubules assembled in vitro. |journal=J. Biol. Chem. |volume=274 |issue= 4 |pages= 2408–15 |year= 1999 |pmid= 9891010 |doi=
*cite journal | author=Parvari R, Hershkovitz E, Grossman N, "et al." |title=Mutation of TBCE causes hypoparathyroidism-retardation-dysmorphism and autosomal recessive Kenny-Caffey syndrome. |journal=Nat. Genet. |volume=32 |issue= 3 |pages= 448–52 |year= 2002 |pmid= 12389028 |doi= 10.1038/ng1012
*cite journal | author=Martin N, Jaubert J, Gounon P, "et al." |title=A missense mutation in Tbce causes progressive motor neuronopathy in mice. |journal=Nat. Genet. |volume=32 |issue= 3 |pages= 443–7 |year= 2002 |pmid= 12389029 |doi= 10.1038/ng1016
*cite journal | author=Bommel H, Xie G, Rossoll W, "et al." |title=Missense mutation in the tubulin-specific chaperone E (Tbce) gene in the mouse mutant progressive motor neuronopathy, a model of human motoneuron disease. |journal=J. Cell Biol. |volume=159 |issue= 4 |pages= 563–9 |year= 2003 |pmid= 12446740 |doi= 10.1083/jcb.200208001
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Gevaert K, Goethals M, Martens L, "et al." |title=Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides. |journal=Nat. Biotechnol. |volume=21 |issue= 5 |pages= 566–9 |year= 2004 |pmid= 12665801 |doi= 10.1038/nbt810
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Rual JF, Venkatesan K, Hao T, "et al." |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209
*cite journal | author=Kimura K, Wakamatsu A, Suzuki Y, "et al." |title=Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. |journal=Genome Res. |volume=16 |issue= 1 |pages= 55–65 |year= 2006 |pmid= 16344560 |doi= 10.1101/gr.4039406
*cite journal | author=Gregory SG, Barlow KF, McLay KE, "et al." |title=The DNA sequence and biological annotation of human chromosome 1. |journal=Nature |volume=441 |issue= 7091 |pages= 315–21 |year= 2006 |pmid= 16710414 |doi= 10.1038/nature04727
*cite journal | author=Kortazar D, Fanarraga ML, Carranza G, "et al." |title=Role of cofactors B (TBCB) and E (TBCE) in tubulin heterodimer dissociation. |journal=Exp. Cell Res. |volume=313 |issue= 3 |pages= 425–36 |year= 2007 |pmid= 17184771 |doi= 10.1016/j.yexcr.2006.09.002

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