- SMTN
Smoothelin, also known as SMTN, is a human
gene .cite web | title = Entrez Gene: SMTN smoothelin| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6525| accessdate = ]PBB_Summary
section_title =
summary_text = This gene encodes a structural protein that is found exclusively in contractile smooth muscle cells. It associates with stress fibers and constitutes part of the cytoskeleton. This gene is localized to chromosome 22q12.3, distal to the TUPLE1 locus and outside the DiGeorge syndrome deletion. Alternative splicing of this gene results in three transcript variants.cite web | title = Entrez Gene: SMTN smoothelin| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6525| accessdate = ]References
Further reading
PBB_Further_reading
citations =
*cite journal | author=Luft FC |title=Differentiating one smooth operator from another. |journal=J. Mol. Med. |volume=77 |issue= 2 |pages= 255–7 |year= 1999 |pmid= 10023778 |doi=
*cite journal | author=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. |journal=Gene |volume=138 |issue= 1-2 |pages= 171–4 |year= 1994 |pmid= 8125298 |doi=
*cite journal | author=van der Loop FT, Schaart G, Timmer ED, "et al." |title=Smoothelin, a novel cytoskeletal protein specific for smooth muscle cells. |journal=J. Cell Biol. |volume=134 |issue= 2 |pages= 401–11 |year= 1996 |pmid= 8707825 |doi=
*cite journal | author=van Eys GJ, Völler MC, Timmer ED, "et al." |title=Smoothelin expression characteristics: development of a smooth muscle cell in vitro system and identification of a vascular variant. |journal=Cell Struct. Funct. |volume=22 |issue= 1 |pages= 65–72 |year= 1997 |pmid= 9113392 |doi=
*cite journal | author=Engelen JJ, Esterling LE, Albrechts JC, "et al." |title=Assignment of the human gene for smoothelin (SMTN) to chromosome 22q12 by fluorescence in situ hybridization and radiation hybrid mapping. |journal=Genomics |volume=43 |issue= 2 |pages= 245–7 |year= 1997 |pmid= 9244445 |doi= 10.1006/geno.1997.9999
*cite journal | author=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, "et al." |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library. |journal=Gene |volume=200 |issue= 1-2 |pages= 149–56 |year= 1997 |pmid= 9373149 |doi=
*cite journal | author= |title=Toward a complete human genome sequence. |journal=Genome Res. |volume=8 |issue= 11 |pages= 1097–108 |year= 1999 |pmid= 9847074 |doi=
*cite journal | author=Krämer J, Aguirre-Arteta AM, Thiel C, "et al." |title=A novel isoform of the smooth muscle cell differentiation marker smoothelin. |journal=J. Mol. Med. |volume=77 |issue= 2 |pages= 294–8 |year= 1999 |pmid= 10023782 |doi=
*cite journal | author=Johansson B, Eriksson A, Ramaekers F, Thornell L |title=Smoothelin in adult and developing human arteries and myocardium. |journal=Histochem. Cell Biol. |volume=112 |issue= 4 |pages= 291–9 |year= 2000 |pmid= 10550614 |doi=
*cite journal | author=Dunham I, Shimizu N, Roe BA, "et al." |title=The DNA sequence of human chromosome 22. |journal=Nature |volume=402 |issue= 6761 |pages= 489–95 |year= 1999 |pmid= 10591208 |doi= 10.1038/990031
*cite journal | author=Gsell S, Eschenhagen T, Kaspareit G, "et al." |title=Apparent up-regulation of stimulatory G-protein alpha subunits in the pregnant human myometrium is mimicked by elevated smoothelin expression. |journal=FASEB J. |volume=14 |issue= 1 |pages= 17–26 |year= 2000 |pmid= 10627276 |doi=
*cite journal | author=Krämer J, Quensel C, Meding J, "et al." |title=Identification and characterization of novel smoothelin isoforms in vascular smooth muscle. |journal=J. Vasc. Res. |volume=38 |issue= 2 |pages= 120–32 |year= 2001 |pmid= 11316948 |doi=
*cite journal | author=Rensen SS, Thijssen VL, De Vries CJ, "et al." |title=Expression of the smoothelin gene is mediated by alternative promoters. |journal=Cardiovasc. Res. |volume=55 |issue= 4 |pages= 850–63 |year= 2002 |pmid= 12176134 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Beausoleil SA, Jedrychowski M, Schwartz D, "et al." |title=Large-scale characterization of HeLa cell nuclear phosphoproteins. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 33 |pages= 12130–5 |year= 2004 |pmid= 15302935 |doi= 10.1073/pnas.0404720101
*cite journal | author=Rual JF, Venkatesan K, Hao T, "et al." |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209PBB_Controls
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