CPSF1

CPSF1

Cleavage and polyadenylation specific factor 1, 160kDa, also known as CPSF1, is a human gene.cite web | title = Entrez Gene: CPSF1 cleavage and polyadenylation specific factor 1, 160kDa| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=29894| accessdate = ]

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References

Further reading

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*cite journal | author=Keller W, Bienroth S, Lang KM, Christofori G |title=Cleavage and polyadenylation factor CPF specifically interacts with the pre-mRNA 3' processing signal AAUAAA. |journal=EMBO J. |volume=10 |issue= 13 |pages= 4241–9 |year= 1992 |pmid= 1756731 |doi=
*cite journal | author=Murthy KG, Manley JL |title=The 160-kD subunit of human cleavage-polyadenylation specificity factor coordinates pre-mRNA 3'-end formation. |journal=Genes Dev. |volume=9 |issue= 21 |pages= 2672–83 |year= 1995 |pmid= 7590244 |doi=
*cite journal | author=Jenny A, Keller W |title=Cloning of cDNAs encoding the 160 kDa subunit of the bovine cleavage and polyadenylation specificity factor. |journal=Nucleic Acids Res. |volume=23 |issue= 14 |pages= 2629–35 |year= 1995 |pmid= 7651824 |doi=
*cite journal | author=Thuresson AC, Aström J, Aström A, "et al." |title=Multiple forms of poly(A) polymerases in human cells. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=91 |issue= 3 |pages= 979–83 |year= 1994 |pmid= 8302877 |doi=
*cite journal | author=Schul W, Groenhout B, Koberna K, "et al." |title=The RNA 3' cleavage factors CstF 64 kDa and CPSF 100 kDa are concentrated in nuclear domains closely associated with coiled bodies and newly synthesized RNA. |journal=EMBO J. |volume=15 |issue= 11 |pages= 2883–92 |year= 1996 |pmid= 8654386 |doi=
*cite journal | author=McCracken S, Fong N, Yankulov K, "et al." |title=The C-terminal domain of RNA polymerase II couples mRNA processing to transcription. |journal=Nature |volume=385 |issue= 6614 |pages= 357–61 |year= 1997 |pmid= 9002523 |doi= 10.1038/385357a0
*cite journal | author=Dantonel JC, Murthy KG, Manley JL, Tora L |title=Transcription factor TFIID recruits factor CPSF for formation of 3' end of mRNA. |journal=Nature |volume=389 |issue= 6649 |pages= 399–402 |year= 1997 |pmid= 9311784 |doi= 10.1038/38763
*cite journal | author=Takagaki Y, Manley JL |title=Complex protein interactions within the human polyadenylation machinery identify a novel component. |journal=Mol. Cell. Biol. |volume=20 |issue= 5 |pages= 1515–25 |year= 2000 |pmid= 10669729 |doi=
*cite journal | author=de Vries H, Rüegsegger U, Hübner W, "et al." |title=Human pre-mRNA cleavage factor II(m) contains homologs of yeast proteins and bridges two other cleavage factors. |journal=EMBO J. |volume=19 |issue= 21 |pages= 5895–904 |year= 2000 |pmid= 11060040 |doi= 10.1093/emboj/19.21.5895
*cite journal | author=Samiotaki M, Balatsos NA, Courtis N, Tsiapalis CM |title=Assignment of the 160-kDa subunit of cleavage and polyadenylation specificity factor (CPSF1) to human chromosome 8q24.23 by radiation hybrid mapping. |journal=Cytogenet. Cell Genet. |volume=90 |issue= 3-4 |pages= 234–5 |year= 2001 |pmid= 11124521 |doi=
*cite journal | author=McCracken S, Lambermon M, Blencowe BJ |title=SRm160 splicing coactivator promotes transcript 3'-end cleavage. |journal=Mol. Cell. Biol. |volume=22 |issue= 1 |pages= 148–60 |year= 2002 |pmid= 11739730 |doi=
*cite journal | author=Maeda Y, Ito M, Harashima N, "et al." |title=Cleavage and polyadenylation specificity factor (CPSF)-derived peptides can induce HLA-A2-restricted and tumor-specific CTLs in the majority of gastrointestinal cancer patients. |journal=Int. J. Cancer |volume=99 |issue= 3 |pages= 409–17 |year= 2002 |pmid= 11992410 |doi= 10.1002/ijc.10377
*cite journal | author=Holland L, Gauthier L, Bell-Rogers P, Yankulov K |title=Distinct parts of minichromosome maintenance protein 2 associate with histone H3/H4 and RNA polymerase II holoenzyme. |journal=Eur. J. Biochem. |volume=269 |issue= 21 |pages= 5192–202 |year= 2002 |pmid= 12392551 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Lehner B, Semple JI, Brown SE, "et al." |title=Analysis of a high-throughput yeast two-hybrid system and its use to predict the function of intracellular proteins encoded within the human MHC class III region. |journal=Genomics |volume=83 |issue= 1 |pages= 153–67 |year= 2004 |pmid= 14667819 |doi=
*cite journal | author=Kaufmann I, Martin G, Friedlein A, "et al." |title=Human Fip1 is a subunit of CPSF that binds to U-rich RNA elements and stimulates poly(A) polymerase. |journal=EMBO J. |volume=23 |issue= 3 |pages= 616–26 |year= 2005 |pmid= 14749727 |doi= 10.1038/sj.emboj.7600070
*cite journal | author=Beausoleil SA, Jedrychowski M, Schwartz D, "et al." |title=Large-scale characterization of HeLa cell nuclear phosphoproteins. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 33 |pages= 12130–5 |year= 2004 |pmid= 15302935 |doi= 10.1073/pnas.0404720101
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504

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  • Cleavage and polyadenylation specificity factor — (CPSF) (or Cleavage polyadenylation stimulating factor) is involved in the cleavage of the 3 signaling region from a newly synthesized pre messenger RNA (pre mRNA) molecule in the process of gene transcription. It is the first protein to bind to… …   Wikipedia

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