ARPC2

Actin related protein 2/3 complex, subunit 2, 34kDa, also known as ARPC2, is a human gene.cite web | title = Entrez Gene: ARPC2 actin related protein 2/3 complex, subunit 2, 34kDa| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10109| accessdate = ]

PBB_Summary
section_title =
summary_text = This gene encodes one of seven subunits of the human Arp2/3 protein complex. The Arp2/3 protein complex has been implicated in the control of actin polymerization in cells and has been conserved through evolution. The exact role of the protein encoded by this gene, the p34 subunit, has yet to be determined. Two alternatively spliced variants have been characterized to date. Additional alternatively spliced variants have been described but their full length nature has not been determined.cite web | title = Entrez Gene: ARPC2 actin related protein 2/3 complex, subunit 2, 34kDa| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10109| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Couch FJ, Rommens JM, Neuhausen SL, "et al." |title=Generation of an integrated transcription map of the BRCA2 region on chromosome 13q12-q13. |journal=Genomics |volume=36 |issue= 1 |pages= 86–99 |year= 1997 |pmid= 8812419 |doi=
*cite journal | author=Welch MD, Iwamatsu A, Mitchison TJ |title=Actin polymerization is induced by Arp2/3 protein complex at the surface of Listeria monocytogenes. |journal=Nature |volume=385 |issue= 6613 |pages= 265–9 |year= 1997 |pmid= 9000076 |doi= 10.1038/385265a0
*cite journal | author=Welch MD, DePace AH, Verma S, "et al." |title=The human Arp2/3 complex is composed of evolutionarily conserved subunits and is localized to cellular regions of dynamic actin filament assembly. |journal=J. Cell Biol. |volume=138 |issue= 2 |pages= 375–84 |year= 1997 |pmid= 9230079 |doi=
*cite journal | author=Machesky LM, Reeves E, Wientjes F, "et al." |title=Mammalian actin-related protein 2/3 complex localizes to regions of lamellipodial protrusion and is composed of evolutionarily conserved proteins. |journal=Biochem. J. |volume=328 ( Pt 1) |issue= |pages= 105–12 |year= 1998 |pmid= 9359840 |doi=
*cite journal | author=Näär AM, Beaurang PA, Zhou S, "et al." |title=Composite co-activator ARC mediates chromatin-directed transcriptional activation. |journal=Nature |volume=398 |issue= 6730 |pages= 828–32 |year= 1999 |pmid= 10235267 |doi= 10.1038/19789
*cite journal | author=Zhao X, Yang Z, Qian M, Zhu X |title=Interactions among subunits of human Arp2/3 complex: p20-Arc as the hub. |journal=Biochem. Biophys. Res. Commun. |volume=280 |issue= 2 |pages= 513–7 |year= 2001 |pmid= 11162547 |doi= 10.1006/bbrc.2000.4151
*cite journal | author=Robinson RC, Turbedsky K, Kaiser DA, "et al." |title=Crystal structure of Arp2/3 complex. |journal=Science |volume=294 |issue= 5547 |pages= 1679–84 |year= 2001 |pmid= 11721045 |doi= 10.1126/science.1066333
*cite journal | author=Gournier H, Goley ED, Niederstrasser H, "et al." |title=Reconstitution of human Arp2/3 complex reveals critical roles of individual subunits in complex structure and activity. |journal=Mol. Cell |volume=8 |issue= 5 |pages= 1041–52 |year= 2002 |pmid= 11741539 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Gevaert K, Goethals M, Martens L, "et al." |title=Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides. |journal=Nat. Biotechnol. |volume=21 |issue= 5 |pages= 566–9 |year= 2004 |pmid= 12665801 |doi= 10.1038/nbt810
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Kaneda A, Kaminishi M, Sugimura T, Ushijima T |title=Decreased expression of the seven ARP2/3 complex genes in human gastric cancers. |journal=Cancer Lett. |volume=212 |issue= 2 |pages= 203–10 |year= 2004 |pmid= 15279900 |doi= 10.1016/j.canlet.2004.03.020
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Andersen JS, Lam YW, Leung AK, "et al." |title=Nucleolar proteome dynamics. |journal=Nature |volume=433 |issue= 7021 |pages= 77–83 |year= 2005 |pmid= 15635413 |doi= 10.1038/nature03207
*cite journal | author=Dubois T, Paléotti O, Mironov AA, "et al." |title=Golgi-localized GAP for Cdc42 functions downstream of ARF1 to control Arp2/3 complex and F-actin dynamics. |journal=Nat. Cell Biol. |volume=7 |issue= 4 |pages= 353–64 |year= 2005 |pmid= 15793564 |doi= 10.1038/ncb1244
*cite journal | author=Cai L, Holoweckyj N, Schaller MD, Bear JE |title=Phosphorylation of coronin 1B by protein kinase C regulates interaction with Arp2/3 and cell motility. |journal=J. Biol. Chem. |volume=280 |issue= 36 |pages= 31913–23 |year= 2005 |pmid= 16027158 |doi= 10.1074/jbc.M504146200
*cite journal | author=Cai L, Marshall TW, Uetrecht AC, "et al." |title=Coronin 1B coordinates Arp2/3 complex and cofilin activities at the leading edge. |journal=Cell |volume=128 |issue= 5 |pages= 915–29 |year= 2007 |pmid= 17350576 |doi= 10.1016/j.cell.2007.01.031
*cite journal | author=Ewing RM, Chu P, Elisma F, "et al." |title=Large-scale mapping of human protein-protein interactions by mass spectrometry. |journal=Mol. Syst. Biol. |volume=3 |issue= |pages= 89 |year= 2007 |pmid= 17353931 |doi= 10.1038/msb4100134

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