NMI (gene)

N-myc (and STAT) interactor, also known as NMI, is a human gene.cite web | title = Entrez Gene: NMI N-myc (and STAT) interactor| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9111| accessdate = ]

PBB_Summary
section_title =
summary_text = NMYC interactor (NMI) encodes a protein that interacts with NMYC and CMYC (two members of the oncogene Myc family), and other transcription factors containing a Zip, HLH, or HLH-Zip motif. The NMI protein also interacts with all STATs except STAT2 and augments STAT-mediated transcription in response to cytokines IL2 and IFN-gamma. The NMI mRNA has low expression levels in all human fetal and adult tissues tested except brain and has high expression in cancer cell line-myeloid leukemias.cite web | title = Entrez Gene: NMI N-myc (and STAT) interactor| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9111| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Bao J, Zervos AS |title=Isolation and characterization of Nmi, a novel partner of Myc proteins. |journal=Oncogene |volume=12 |issue= 10 |pages= 2171–6 |year= 1996 |pmid= 8668343 |doi=
*cite journal | author=Lebrun SJ, Shpall RL, Naumovski L |title=Interferon-induced upregulation and cytoplasmic localization of Myc-interacting protein Nmi. |journal=J. Interferon Cytokine Res. |volume=18 |issue= 9 |pages= 767–71 |year= 1998 |pmid= 9781816 |doi=
*cite journal | author=Zhu M, John S, Berg M, Leonard WJ |title=Functional association of Nmi with Stat5 and Stat1 in IL-2- and IFNgamma-mediated signaling. |journal=Cell |volume=96 |issue= 1 |pages= 121–30 |year= 1999 |pmid= 9989503 |doi=
*cite journal | author=Lee ND, Chen J, Shpall RL, Naumovski L |title=Subcellular localization of interferon-inducible Myc/stat-interacting protein Nmi is regulated by a novel IFP 35 homologous domain. |journal=J. Interferon Cytokine Res. |volume=19 |issue= 11 |pages= 1245–52 |year= 1999 |pmid= 10574616 |doi= 10.1089/107999099312902
*cite journal | author=Bannasch D, Weis I, Schwab M |title=Nmi protein interacts with regions that differ between MycN and Myc and is localized in the cytoplasm of neuroblastoma cells in contrast to nuclear MycN. |journal=Oncogene |volume=18 |issue= 48 |pages= 6810–7 |year= 2000 |pmid= 10597290 |doi= 10.1038/sj.onc.1203090
*cite journal | author=Zhou X, Liao J, Meyerdierks A, "et al." |title=Interferon-alpha induces nmi-IFP35 heterodimeric complex formation that is affected by the phosphorylation of IFP35. |journal=J. Biol. Chem. |volume=275 |issue= 28 |pages= 21364–71 |year= 2000 |pmid= 10779520 |doi= 10.1074/jbc.M003177200
*cite journal | author=Chen J, Shpall RL, Meyerdierks A, "et al." |title=Interferon-inducible Myc/STAT-interacting protein Nmi associates with IFP 35 into a high molecular mass complex and inhibits proteasome-mediated degradation of IFP 35. |journal=J. Biol. Chem. |volume=275 |issue= 46 |pages= 36278–84 |year= 2000 |pmid= 10950963 |doi= 10.1074/jbc.M006975200
*cite journal | author=Chen J, Naumovski L |title=Intracellular redistribution of interferon-inducible proteins Nmi and IFP 35 in apoptotic cells. |journal=J. Interferon Cytokine Res. |volume=22 |issue= 2 |pages= 237–43 |year= 2002 |pmid= 11911807 |doi= 10.1089/107999002753536211
*cite journal | author=Li H, Lee TH, Avraham H |title=A novel tricomplex of BRCA1, Nmi, and c-Myc inhibits c-Myc-induced human telomerase reverse transcriptase gene (hTERT) promoter activity in breast cancer. |journal=J. Biol. Chem. |volume=277 |issue= 23 |pages= 20965–73 |year= 2002 |pmid= 11916966 |doi= 10.1074/jbc.M112231200
*cite journal | author=Sun GJ, Tong X, Dong Y, "et al." |title= [Identification of a protein interacting with apoptin from human leucocyte cDNA library by using yeast two-hybrid screening] |journal=Sheng Wu Hua Xue Yu Sheng Wu Wu Li Xue Bao |volume=34 |issue= 3 |pages= 369–72 |year= 2002 |pmid= 12019454 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Lehner B, Sanderson CM |title=A protein interaction framework for human mRNA degradation. |journal=Genome Res. |volume=14 |issue= 7 |pages= 1315–23 |year= 2004 |pmid= 15231747 |doi= 10.1101/gr.2122004
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Hillier LW, Graves TA, Fulton RS, "et al." |title=Generation and annotation of the DNA sequences of human chromosomes 2 and 4. |journal=Nature |volume=434 |issue= 7034 |pages= 724–31 |year= 2005 |pmid= 15815621 |doi= 10.1038/nature03466
*cite journal | author=Jung HH, Lee J, Kim JH, "et al." |title=STAT1 and Nmi are downstream targets of Ets-1 transcription factor in MCF-7 human breast cancer cell. |journal=FEBS Lett. |volume=579 |issue= 18 |pages= 3941–6 |year= 2005 |pmid= 15996661 |doi= 10.1016/j.febslet.2005.06.011
*cite journal | author=Rual JF, Venkatesan K, Hao T, "et al." |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209
*cite journal | author=Schlierf B, Lang S, Kosian T, "et al." |title=The high-mobility group transcription factor Sox10 interacts with the N-myc-interacting protein Nmi. |journal=J. Mol. Biol. |volume=353 |issue= 5 |pages= 1033–42 |year= 2005 |pmid= 16214168 |doi= 10.1016/j.jmb.2005.09.013
*cite journal | author=Zhang L, Tang Y, Tie Y, "et al." |title=The PH domain containing protein CKIP-1 binds to IFP35 and Nmi and is involved in cytokine signaling. |journal=Cell. Signal. |volume=19 |issue= 5 |pages= 932–44 |year= 2007 |pmid= 17197158 |doi= 10.1016/j.cellsig.2006.11.002
*cite journal | author=Albihn A, Mo H, Yang Y, Henriksson M |title=Camptothecin-induced apoptosis is enhanced by Myc and involves PKCdelta signaling. |journal=Int. J. Cancer |volume=121 |issue= 8 |pages= 1821–9 |year= 2007 |pmid= 17565738 |doi= 10.1002/ijc.22866

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