SKAP2

Src kinase associated phosphoprotein 2, also known as SKAP2, is a human gene.cite web | title = Entrez Gene: SKAP2 src kinase associated phosphoprotein 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=8935| accessdate = ]

PBB_Summary
section_title =
summary_text = The protein encoded by this gene belongs to the src family kinases. This protein is similar to the src kinase associated phosphoprotein 1. It is an adaptor protein that is thought to play an essential role in the src signaling pathway in various cells. It inhibits PTK2B/RAFTK activity and regulates alpha-synuclein phosphorylation.cite web | title = Entrez Gene: SKAP2 src kinase associated phosphoprotein 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=8935| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. |journal=Gene |volume=138 |issue= 1-2 |pages= 171–4 |year= 1994 |pmid= 8125298 |doi=
*cite journal | author=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, "et al." |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library. |journal=Gene |volume=200 |issue= 1-2 |pages= 149–56 |year= 1997 |pmid= 9373149 |doi=
*cite journal | author=Liu J, Kang H, Raab M, "et al." |title=FYB (FYN binding protein) serves as a binding partner for lymphoid protein and FYN kinase substrate SKAP55 and a SKAP55-related protein in T cells. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=95 |issue= 15 |pages= 8779–84 |year= 1998 |pmid= 9671755 |doi=
*cite journal | author=Marie-Cardine A, Verhagen AM, Eckerskorn C, Schraven B |title=SKAP-HOM, a novel adaptor protein homologous to the FYN-associated protein SKAP55. |journal=FEBS Lett. |volume=435 |issue= 1 |pages= 55–60 |year= 1998 |pmid= 9755858 |doi=
*cite journal | author=Kouroku Y, Soyama A, Fujita E, "et al." |title=RA70 is a src kinase-associated protein expressed ubiquitously. |journal=Biochem. Biophys. Res. Commun. |volume=252 |issue= 3 |pages= 738–42 |year= 1999 |pmid= 9837776 |doi= 10.1006/bbrc.1998.9637
*cite journal | author=Wang X, Stollar BD |title=Immunoglobulin VH gene expression in human aging. |journal=Clin. Immunol. |volume=93 |issue= 2 |pages= 132–42 |year= 1999 |pmid= 10527689 |doi= 10.1006/clim.1999.4781
*cite journal | author=Asazuma N, Wilde JI, Berlanga O, "et al." |title=Interaction of linker for activation of T cells with multiple adapter proteins in platelets activated by the glycoprotein VI-selective ligand, convulxin. |journal=J. Biol. Chem. |volume=275 |issue= 43 |pages= 33427–34 |year= 2000 |pmid= 10942756 |doi= 10.1074/jbc.M001439200
*cite journal | author=Curtis DJ, Jane SM, Hilton DJ, "et al." |title=Adaptor protein SKAP55R is associated with myeloid differentiation and growth arrest. |journal=Exp. Hematol. |volume=28 |issue= 11 |pages= 1250–9 |year= 2001 |pmid= 11063873 |doi=
*cite journal | author=Moog-Lutz C, Peterson EJ, Lutz PG, "et al." |title=PRAM-1 is a novel adaptor protein regulated by retinoic acid (RA) and promyelocytic leukemia (PML)-RA receptor alpha in acute promyelocytic leukemia cells. |journal=J. Biol. Chem. |volume=276 |issue= 25 |pages= 22375–81 |year= 2001 |pmid= 11301322 |doi= 10.1074/jbc.M011683200
*cite journal | author=Kirchgessner H, Dietrich J, Scherer J, "et al." |title=The transmembrane adaptor protein TRIM regulates T cell receptor (TCR) expression and TCR-mediated signaling via an association with the TCR zeta chain. |journal=J. Exp. Med. |volume=193 |issue= 11 |pages= 1269–84 |year= 2001 |pmid= 11390434 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Scherer SW, Cheung J, MacDonald JR, "et al." |title=Human chromosome 7: DNA sequence and biology. |journal=Science |volume=300 |issue= 5620 |pages= 767–72 |year= 2003 |pmid= 12690205 |doi= 10.1126/science.1083423
*cite journal | author=Hillier LW, Fulton RS, Fulton LA, "et al." |title=The DNA sequence of human chromosome 7. |journal=Nature |volume=424 |issue= 6945 |pages= 157–64 |year= 2003 |pmid= 12853948 |doi= 10.1038/nature01782
*cite journal | author=Takahashi T, Yamashita H, Nagano Y, "et al." |title=Identification and characterization of a novel Pyk2/related adhesion focal tyrosine kinase-associated protein that inhibits alpha-synuclein phosphorylation. |journal=J. Biol. Chem. |volume=278 |issue= 43 |pages= 42225–33 |year= 2004 |pmid= 12893833 |doi= 10.1074/jbc.M213217200
*cite journal | author=Park SY, Avraham HK, Avraham S |title=RAFTK/Pyk2 activation is mediated by trans-acting autophosphorylation in a Src-independent manner. |journal=J. Biol. Chem. |volume=279 |issue= 32 |pages= 33315–22 |year= 2004 |pmid= 15166227 |doi= 10.1074/jbc.M313527200
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Barrios-Rodiles M, Brown KR, Ozdamar B, "et al." |title=High-throughput mapping of a dynamic signaling network in mammalian cells. |journal=Science |volume=307 |issue= 5715 |pages= 1621–5 |year= 2005 |pmid= 15761153 |doi= 10.1126/science.1105776
*cite journal | author=Rual JF, Venkatesan K, Hao T, "et al." |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209
*cite journal | author=Olsen JV, Blagoev B, Gnad F, "et al." |title=Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. |journal=Cell |volume=127 |issue= 3 |pages= 635–48 |year= 2006 |pmid= 17081983 |doi= 10.1016/j.cell.2006.09.026

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