Phospholipase A2, group IVC (cytosolic, calcium-independent), also known as PLA2G4C, is a human gene.cite web | title = Entrez Gene: PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent)| url =| accessdate = ]

section_title =
summary_text =


Further reading

citations =
*cite journal | author=Schröder HC, Perovic S, Kavsan V, "et al." |title=Mechanisms of prionSc- and HIV-1 gp120 induced neuronal cell death. |journal=Neurotoxicology |volume=19 |issue= 4-5 |pages= 683–8 |year= 1998 |pmid= 9745929 |doi=
*cite journal | author=Wu T, Angus CW, Yao XL, "et al." |title=P11, a unique member of the S100 family of calcium-binding proteins, interacts with and inhibits the activity of the 85-kDa cytosolic phospholipase A2. |journal=J. Biol. Chem. |volume=272 |issue= 27 |pages= 17145–53 |year= 1997 |pmid= 9202034 |doi=
*cite journal | author=Mavoungou E, Georges-Courbot MC, Poaty-Mavoungou V, "et al." |title=HIV and SIV envelope glycoproteins induce phospholipase A2 activation in human and macaque lymphocytes. |journal=J. Acquir. Immune Defic. Syndr. Hum. Retrovirol. |volume=16 |issue= 1 |pages= 1–9 |year= 1997 |pmid= 9377118 |doi=
*cite journal | author=Underwood KW, Song C, Kriz RW, "et al." |title=A novel calcium-independent phospholipase A2, cPLA2-gamma, that is prenylated and contains homology to cPLA2. |journal=J. Biol. Chem. |volume=273 |issue= 34 |pages= 21926–32 |year= 1998 |pmid= 9705332 |doi=
*cite journal | author=Pickard RT, Strifler BA, Kramer RM, Sharp JD |title=Molecular cloning of two new human paralogs of 85-kDa cytosolic phospholipase A2. |journal=J. Biol. Chem. |volume=274 |issue= 13 |pages= 8823–31 |year= 1999 |pmid= 10085124 |doi=
*cite journal | author=Smith JS, Tachibana I, Pohl U, "et al." |title=A transcript map of the chromosome 19q-arm glioma tumor suppressor region. |journal=Genomics |volume=64 |issue= 1 |pages= 44–50 |year= 2000 |pmid= 10708517 |doi= 10.1006/geno.1999.6101
*cite journal | author=Hartmann C, Johnk L, Sasaki H, "et al." |title=Novel PLA2G4C polymorphism as a molecular diagnostic assay for 19q loss in human gliomas. |journal=Brain Pathol. |volume=12 |issue= 2 |pages= 178–82 |year= 2002 |pmid= 11958371 |doi=
*cite journal | author=Stewart A, Ghosh M, Spencer DM, Leslie CC |title=Enzymatic properties of human cytosolic phospholipase A(2)gamma. |journal=J. Biol. Chem. |volume=277 |issue= 33 |pages= 29526–36 |year= 2002 |pmid= 12039969 |doi= 10.1074/jbc.M204856200
*cite journal | author=Lindbom J, Ljungman AG, Lindahl M, Tagesson C |title=Increased gene expression of novel cytosolic and secretory phospholipase A(2) types in human airway epithelial cells induced by tumor necrosis factor-alpha and IFN-gamma. |journal=J. Interferon Cytokine Res. |volume=22 |issue= 9 |pages= 947–55 |year= 2003 |pmid= 12396716 |doi= 10.1089/10799900260286650
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Asai K, Hirabayashi T, Houjou T, "et al." |title=Human group IVC phospholipase A2 (cPLA2gamma). Roles in the membrane remodeling and activation induced by oxidative stress. |journal=J. Biol. Chem. |volume=278 |issue= 10 |pages= 8809–14 |year= 2003 |pmid= 12502717 |doi= 10.1074/jbc.M212117200
*cite journal | author=Jenkins CM, Han X, Yang J, "et al." |title=Purification of recombinant human cPLA2 gamma and identification of C-terminal farnesylation, proteolytic processing, and carboxymethylation by MALDI-TOF-TOF analysis. |journal=Biochemistry |volume=42 |issue= 40 |pages= 11798–807 |year= 2004 |pmid= 14529291 |doi= 10.1021/bi034611q
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Dong M, Johnson M, Rezaie A, "et al." |title=Cytoplasmic phospholipase A2 levels correlate with apoptosis in human colon tumorigenesis. |journal=Clin. Cancer Res. |volume=11 |issue= 6 |pages= 2265–71 |year= 2005 |pmid= 15788676 |doi= 10.1158/1078-0432.CCR-04-1079
*cite journal | author=Yan W, Jenkins CM, Han X, "et al." |title=The highly selective production of 2-arachidonoyl lysophosphatidylcholine catalyzed by purified calcium-independent phospholipase A2gamma: identification of a novel enzymatic mediator for the generation of a key branch point intermediate in eicosanoid signaling. |journal=J. Biol. Chem. |volume=280 |issue= 29 |pages= 26669–79 |year= 2005 |pmid= 15908428 |doi= 10.1074/jbc.M502358200
*cite journal | author=Yamashita A, Kamata R, Kawagishi N, "et al." |title=Roles of C-terminal processing, and involvement in transacylation reaction of human group IVC phospholipase A2 (cPLA2gamma). |journal=J. Biochem. |volume=137 |issue= 5 |pages= 557–67 |year= 2005 |pmid= 15944408 |doi= 10.1093/jb/mvi067
*cite journal | author=Zhao X, Wang D, Zhao Z, "et al." |title=Caspase-3-dependent activation of calcium-independent phospholipase A2 enhances cell migration in non-apoptotic ovarian cancer cells. |journal=J. Biol. Chem. |volume=281 |issue= 39 |pages= 29357–68 |year= 2006 |pmid= 16882668 |doi= 10.1074/jbc.M513105200
*cite journal | author=Mancuso DJ, Han X, Jenkins CM, "et al." |title=Dramatic accumulation of triglycerides and precipitation of cardiac hemodynamic dysfunction during brief caloric restriction in transgenic myocardium expressing human calcium-independent phospholipase A2gamma. |journal=J. Biol. Chem. |volume=282 |issue= 12 |pages= 9216–27 |year= 2007 |pmid= 17213206 |doi= 10.1074/jbc.M607307200

update_page = yes
require_manual_inspection = no
update_protein_box = yes
update_summary = yes
update_citations = yes

Wikimedia Foundation. 2010.

Игры ⚽ Поможем написать курсовую

Look at other dictionaries:

  • Phospholipase A₂ — Masse/Länge Primärstruktur ca. 120 Aminosäuren …   Deutsch Wikipedia

  • Phospholipase A2 — Phospholipases A2 (PLA2s) EC number| are upstream regulators of many inflammatory processes. This particular phospholipase specifically recognizes the sn 2 acyl bond of phospholipids and catalytically hydrolyzes the bond releasing… …   Wikipedia

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”