SMURF2

SMURF2

SMAD specific E3 ubiquitin protein ligase 2, also known as SMURF2, is a human gene.cite web | title = Entrez Gene: SMURF2 SMAD specific E3 ubiquitin protein ligase 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=64750| accessdate = ]

PBB_Summary
section_title =
summary_text =

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Lin X, Liang M, Feng XH |title=Smurf2 is a ubiquitin E3 ligase mediating proteasome-dependent degradation of Smad2 in transforming growth factor-beta signaling. |journal=J. Biol. Chem. |volume=275 |issue= 47 |pages= 36818–22 |year= 2001 |pmid= 11016919 |doi= 10.1074/jbc.C000580200
*cite journal | author=Zhang Y, Chang C, Gehling DJ, "et al." |title=Regulation of Smad degradation and activity by Smurf2, an E3 ubiquitin ligase. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=98 |issue= 3 |pages= 974–9 |year= 2001 |pmid= 11158580 |doi= 10.1073/pnas.98.3.974
*cite journal | author=Kavsak P, Rasmussen RK, Causing CG, "et al." |title=Smad7 binds to Smurf2 to form an E3 ubiquitin ligase that targets the TGF beta receptor for degradation. |journal=Mol. Cell |volume=6 |issue= 6 |pages= 1365–75 |year= 2001 |pmid= 11163210 |doi=
*cite journal | author=Bonni S, Wang HR, Causing CG, "et al." |title=TGF-beta induces assembly of a Smad2-Smurf2 ubiquitin ligase complex that targets SnoN for degradation. |journal=Nat. Cell Biol. |volume=3 |issue= 6 |pages= 587–95 |year= 2001 |pmid= 11389444 |doi= 10.1038/35078562
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Subramaniam V, Li H, Wong M, "et al." |title=The RING-H2 protein RNF11 is overexpressed in breast cancer and is a target of Smurf2 E3 ligase. |journal=Br. J. Cancer |volume=89 |issue= 8 |pages= 1538–44 |year= 2003 |pmid= 14562029 |doi= 10.1038/sj.bjc.6601301
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Asano Y, Ihn H, Yamane K, "et al." |title=Impaired Smad7-Smurf-mediated negative regulation of TGF-beta signaling in scleroderma fibroblasts. |journal=J. Clin. Invest. |volume=113 |issue= 2 |pages= 253–64 |year= 2004 |pmid= 14722617 |doi= 10.1172/JCI200416269
*cite journal | author=Li H, Seth A |title=An RNF11: Smurf2 complex mediates ubiquitination of the AMSH protein. |journal=Oncogene |volume=23 |issue= 10 |pages= 1801–8 |year= 2004 |pmid= 14755250 |doi= 10.1038/sj.onc.1207319
*cite journal | author=Jin YH, Jeon EJ, Li QL, "et al." |title=Transforming growth factor-beta stimulates p300-dependent RUNX3 acetylation, which inhibits ubiquitination-mediated degradation. |journal=J. Biol. Chem. |volume=279 |issue= 28 |pages= 29409–17 |year= 2004 |pmid= 15138260 |doi= 10.1074/jbc.M313120200
*cite journal | author=Brandenberger R, Wei H, Zhang S, "et al." |title=Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation. |journal=Nat. Biotechnol. |volume=22 |issue= 6 |pages= 707–16 |year= 2005 |pmid= 15146197 |doi= 10.1038/nbt971
*cite journal | author=Colland F, Jacq X, Trouplin V, "et al." |title=Functional proteomics mapping of a human signaling pathway. |journal=Genome Res. |volume=14 |issue= 7 |pages= 1324–32 |year= 2004 |pmid= 15231748 |doi= 10.1101/gr.2334104
*cite journal | author=Suzuki Y, Yamashita R, Shirota M, "et al." |title=Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions. |journal=Genome Res. |volume=14 |issue= 9 |pages= 1711–8 |year= 2004 |pmid= 15342556 |doi= 10.1101/gr.2435604
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Zhang H, Cohen SN |title=Smurf2 up-regulation activates telomere-dependent senescence. |journal=Genes Dev. |volume=18 |issue= 24 |pages= 3028–40 |year= 2005 |pmid= 15574587 |doi= 10.1101/gad.1253004
*cite journal | author=Barrios-Rodiles M, Brown KR, Ozdamar B, "et al." |title=High-throughput mapping of a dynamic signaling network in mammalian cells. |journal=Science |volume=307 |issue= 5715 |pages= 1621–5 |year= 2005 |pmid= 15761153 |doi= 10.1126/science.1105776
*cite journal | author=Ohashi N, Yamamoto T, Uchida C, "et al." |title=Transcriptional induction of Smurf2 ubiquitin ligase by TGF-beta. |journal=FEBS Lett. |volume=579 |issue= 12 |pages= 2557–63 |year= 2005 |pmid= 15862290 |doi= 10.1016/j.febslet.2005.03.069
*cite journal | author=Ogunjimi AA, Briant DJ, Pece-Barbara N, "et al." |title=Regulation of Smurf2 ubiquitin ligase activity by anchoring the E2 to the HECT domain. |journal=Mol. Cell |volume=19 |issue= 3 |pages= 297–308 |year= 2005 |pmid= 16061177 |doi= 10.1016/j.molcel.2005.06.028
*cite journal | author=Chong PA, Lin H, Wrana JL, Forman-Kay JD |title=An expanded WW domain recognition motif revealed by the interaction between Smad7 and the E3 ubiquitin ligase Smurf2. |journal=J. Biol. Chem. |volume=281 |issue= 25 |pages= 17069–75 |year= 2006 |pmid= 16641086 |doi= 10.1074/jbc.M601493200
*cite journal | author=Wiesner S, Ogunjimi AA, Wang HR, "et al." |title=Autoinhibition of the HECT-type ubiquitin ligase Smurf2 through its C2 domain. |journal=Cell |volume=130 |issue= 4 |pages= 651–62 |year= 2007 |pmid= 17719543 |doi= 10.1016/j.cell.2007.06.050

PBB_Controls
update_page = yes
require_manual_inspection = no
update_protein_box = yes
update_summary = yes
update_citations = yes


Wikimedia Foundation. 2010.

Игры ⚽ Поможем написать курсовую

Look at other dictionaries:

  • Mothers against decapentaplegic homolog 7 — SMAD family member 7 Solution Structure Of Smurf2 Ww3 Domain Smad7 Py Peptide Complex Identifiers Symbols …   Wikipedia

  • Mothers against decapentaplegic homolog 2 — SMAD family member 2 PDB rendering based on 1dev …   Wikipedia

  • Ubiquitina C — Estructura tridimensional de la ubiquitina C. HUGO 12468 …   Wikipedia Español

  • TGF beta signaling pathway — The Transforming growth factor beta (TGFβ) signaling pathway is involved in many cellular processes in both the adult organism and the developing embryo including cell growth, cell differentiation, apoptosis, cellular homeostasis and other… …   Wikipedia

  • RNF11 — Ring finger protein 11, also known as RNF11, is a human gene.cite web | title = Entrez Gene: RNF11 ring finger protein 11| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene Cmd=ShowDetailView TermToSearch=26994| accessdate = ] PBB Summary… …   Wikipedia

  • La protéine SnoN — SnoN La SnoN est une protéine. L’équilibre dans la régulation de la voie de signalisation de la cytokine TGF β est un facteur important de plusieurs pathologies. La surexpression tout comme la diminution de l’activité des protéines Ski et SnoN… …   Wikipédia en Français

  • SnoN — La SnoN est une protéine. L’équilibre dans la régulation de la voie de signalisation de la cytokine TGF β est un facteur important de plusieurs pathologies. La surexpression tout comme la diminution de l’activité des protéines Ski et SnoN sont… …   Wikipédia en Français

  • Mothers against decapentaplegic homolog 1 — SMAD family member 1 PDB rendering based on 1khu …   Wikipedia

  • C2 domain — Pfam box Symbol = C2 Name = C2 domain width =200 caption = The C2 domain of C.absonum α toxin (PDB 1OLP). β strands are shown in yellow. Co ordinated Calcium ions are in cyan Pfam= PF00168 InterPro= IPR000008 SMART= C2 PROSITE = PDOC00380 SCOP =… …   Wikipedia

  • RPS27A — Ribosomal protein S27a, also known as RPS27A, is a human gene.cite web | title = Entrez Gene: RPS27A ribosomal protein S27a| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene Cmd=ShowDetailView TermToSearch=6233| accessdate = ] PBB Summary… …   Wikipedia

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”