UCK2

Uridine-cytidine kinase 2, also known as UCK2, is a human gene.cite web | title = Entrez Gene: UCK2 uridine-cytidine kinase 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=7371| accessdate = ]

PBB_Summary
section_title =
summary_text = The protein encoded by this gene catalyzes the phosphorylation of uridine monophosphate to uridine diphosphate. This is the first step in the production of the pyrimidine nucleoside triphosphates required for RNA and DNA synthesis. In addition, an allele of this gene may play a role in mediating nonhumoral immunity to Hemophilus influenzae type B.cite web | title = Entrez Gene: UCK2 uridine-cytidine kinase 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=7371| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Satlin A, Kucherlapati R, Ruddle FH |title=Assignment of the gene for human uridine monophosphate kinase to chromosome 1 using somatic cell hybrid clone panels. |journal=Cytogenet. Cell Genet. |volume=15 |issue= 3 |pages= 146–52 |year= 1976 |pmid= 172293 |doi=
*cite journal | author=Jamil TP, Swallow DM, Povey S |title=A comparative study of the age-related patterns of decay of some nucleoside monophosphate kinases in human red cells. |journal=Biochem. Genet. |volume=16 |issue= 11-12 |pages= 1219–32 |year= 1979 |pmid= 220950 |doi=
*cite journal | author=Ozaki K, Kuroki T, Hayashi S, Nakamura Y |title=Isolation of three testis-specific genes (TSA303, TSA806, TSA903) by a differential mRNA display method. |journal=Genomics |volume=36 |issue= 2 |pages= 316–9 |year= 1997 |pmid= 8812458 |doi= 10.1006/geno.1996.0467
*cite journal | author=Van Rompay AR, Johansson M, Karlsson A |title=Phosphorylation of deoxycytidine analog monophosphates by UMP-CMP kinase: molecular characterization of the human enzyme. |journal=Mol. Pharmacol. |volume=56 |issue= 3 |pages= 562–9 |year= 1999 |pmid= 10462544 |doi=
*cite journal | author=Van Rompay AR, Norda A, Lindén K, "et al." |title=Phosphorylation of uridine and cytidine nucleoside analogs by two human uridine-cytidine kinases. |journal=Mol. Pharmacol. |volume=59 |issue= 5 |pages= 1181–6 |year= 2001 |pmid= 11306702 |doi=
*cite journal | author=Komatsu N, Kimura Y, Kido A, Oya M |title=Polymorphism of uridine monophosphate kinase: population study in Japanese and phenotyping in bloodstains. |journal=Int. J. Legal Med. |volume=104 |issue= 1 |pages= 13–6 |year= 2001 |pmid= 11453085 |doi=
*cite journal | author=Koizumi K, Shimamoto Y, Azuma A, "et al." |title=Cloning and expression of uridine/cytidine kinase cDNA from human fibrosarcoma cells. |journal=Int. J. Mol. Med. |volume=8 |issue= 3 |pages= 273–8 |year= 2001 |pmid= 11494055 |doi=
*cite journal | author=Pearman AT, Castro-Faria-Neto HC, McIntyre TM, "et al." |title=Characterization of human UMP-CMP kinase enzymatic activity and 5' untranslated region. |journal=Life Sci. |volume=69 |issue= 20 |pages= 2361–70 |year= 2001 |pmid= 11681623 |doi=
*cite journal | author=Liou JY, Dutschman GE, Lam W, "et al." |title=Characterization of human UMP/CMP kinase and its phosphorylation of D- and L-form deoxycytidine analogue monophosphates. |journal=Cancer Res. |volume=62 |issue= 6 |pages= 1624–31 |year= 2002 |pmid= 11912132 |doi=
*cite journal | author=Kashuba E, Kashuba V, Sandalova T, "et al." |title=Epstein-Barr virus encoded nuclear protein EBNA-3 binds a novel human uridine kinase/uracil phosphoribosyltransferase. |journal=BMC Cell Biol. |volume=3 |issue= |pages= 23 |year= 2002 |pmid= 12199906 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Gevaert K, Goethals M, Martens L, "et al." |title=Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides. |journal=Nat. Biotechnol. |volume=21 |issue= 5 |pages= 566–9 |year= 2004 |pmid= 12665801 |doi= 10.1038/nbt810
*cite journal | author=Pasti C, Gallois-Montbrun S, Munier-Lehmann H, "et al." |title=Reaction of human UMP-CMP kinase with natural and analog substrates. |journal=Eur. J. Biochem. |volume=270 |issue= 8 |pages= 1784–90 |year= 2003 |pmid= 12694191 |doi=
*cite journal | author=Suzuki NN, Koizumi K, Fukushima M, "et al." |title=Crystallization and preliminary X-ray analysis of human uridine-cytidine kinase 2. |journal=Acta Crystallogr. D Biol. Crystallogr. |volume=59 |issue= Pt 8 |pages= 1477–8 |year= 2004 |pmid= 12876357 |doi=
*cite journal | author=Suzuki NN, Koizumi K, Fukushima M, "et al." |title=Structural basis for the specificity, catalysis, and regulation of human uridine-cytidine kinase. |journal=Structure |volume=12 |issue= 5 |pages= 751–64 |year= 2005 |pmid= 15130468 |doi= 10.1016/j.str.2004.02.038
*cite journal | author=Murata D, Endo Y, Obata T, "et al." |title=A crucial role of uridine/cytidine kinase 2 in antitumor activity of 3'-ethynyl nucleosides. |journal=Drug Metab. Dispos. |volume=32 |issue= 10 |pages= 1178–82 |year= 2005 |pmid= 15280220 |doi= 10.1124/dmd.104.000737
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Aldenhoven J, Chen Y, Moran C |title=Assignment of UCK2, ATF3 and RGS18 from human chromosome 1 to porcine chromosomes 4, 9 and 10 with somatic and radiation hybrid panels. |journal=Cytogenet. Genome Res. |volume=112 |issue= 3-4 |pages= 341F |year= 2006 |pmid= 16484797 |doi= 10.1159/000089896
*cite journal | author=Gregory SG, Barlow KF, McLay KE, "et al." |title=The DNA sequence and biological annotation of human chromosome 1. |journal=Nature |volume=441 |issue= 7091 |pages= 315–21 |year= 2006 |pmid= 16710414 |doi= 10.1038/nature04727

PBB_Controls
update_page = yes
require_manual_inspection = no
update_protein_box = yes
update_summary = yes
update_citations = yes